Relation of Stroke and Bleeding Risk Profiles to Efficacy and Safety of Edoxaban for Cardioversion of Atrial Fibrillation (from the EdoxabaN versus warfarin in subjectS UndeRgoing cardiovErsion of Atrial Fibrillation [ENSURE-AF] Study)

• Published in: The American Journal of Cardiology Vol. 121; no. 2; pp. 193 - 198
• Main Authors: Lip, Gregory Y.H., Merino, Jose L., Dan, G. Andrei, Themistoclakis, Sakis, Ellenbogen, Kenneth A., De Caterina, Raffaele, Goudev, Assen, Jin, James, Melino, Michael, Winters, Shannon M., Goette, Andreas
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.01.2018; Elsevier BV; Elsevier Limited
• Subjects: Age; Aged; Anti-inflammatory agents; Anticoagulants; Anticoagulants - therapeutic use; Aspirin; Atrial Fibrillation; Atrial Fibrillation - complications; Atrial Fibrillation - therapy; Bleeding; Cardiac arrhythmia; Cardiology and Cardiovascular Medicine; Cardiovascular Diseases; Cardiovascular Diseases - mortality; Cerebral infarction; Cerebro; Congestive heart failure; Diabetes mellitus; Effectiveness; Electric Countershock; Embolism; Embolism - epidemiology; Embolism - prevention & control; Enfermedad cardiovascular; Enoxaparin; Enoxaparin - therapeutic use; Factor Xa Inhibitors; Factor Xa Inhibitors - therapeutic use; Female; Fibrillation; Geriatrics; Heart; Hemorragia cerebral; Hemorrhage; Hemorrhage - chemically induced; Hemorrhage - epidemiology; Humans; Hypertension; Inflammation; International Normalized Ratio; Male; Middle Aged; Myocardial Infarction; Myocardial Infarction - epidemiology; Myocardial Infarction - prevention & control; Older people; Patients; Pyridines; Pyridines - therapeutic use; Risk; Safety; Statistical analysis; Stroke; Stroke - etiology; Stroke - prevention & control; Thiazoles; Thiazoles - therapeutic use; Thromboembolism; Thromboembolism - epidemiology; Thromboembolism - prevention & control; Vascular diseases; Warfarin; Warfarin - therapeutic use

In the EdoxabaN versus warfarin in subjectS UndeRgoing cardiovErsion of Atrial Fibrillation (ENSURE-AF) study, edoxaban was compared with enoxaparin–warfarin in patients who underwent electrical cardioversion of nonvalvular atrial fibrillation, showing comparable low rates of bleeding and thromboemb...