GORE® CARDIOFORM ASD occluder thrombus in a patient of rheumatoid arthritis occurred three days after deployment
A 67-year-old female patient with rheumatoid arthritis that was well suppressed by medications except for steroids had catheter closure of the secundum atrial septal defect (ASD). After the administration of aspirin and intravenous heparin, a 32-mm of GORE® CARDIOFORM ASD occluder was successfully d...
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| Published in | International journal of cardiology congenital heart disease Vol. 21; p. 100600 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
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Elsevier B.V
01.09.2025
Elsevier |
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| Abstract | A 67-year-old female patient with rheumatoid arthritis that was well suppressed by medications except for steroids had catheter closure of the secundum atrial septal defect (ASD). After the administration of aspirin and intravenous heparin, a 32-mm of GORE® CARDIOFORM ASD occluder was successfully deployed. On postprocedural day 3, transthoracic echocardiography showed mobile echogenic mass of 9 mm on the right side of the device. Intravenous heparin 10 IU/kg/hr was administrated continuously, and clopidogrel was added. On the following day, the mobile mass was not visible. Even though the occurrence rate of device thrombus is not high, device thrombosis can become a major complication of device closure of ASD because it may cause systemic and/or pulmonary embolism. Administration of dual antiplatelet therapy or other anticoagulant therapy should be considered if the patients have a higher risk of thrombosis. |
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| AbstractList | AbstractA 67-year-old female patient with rheumatoid arthritis that was well suppressed by medications except for steroids had catheter closure of the secundum atrial septal defect (ASD). After the administration of aspirin and intravenous heparin, a 32-mm of GORE® CARDIOFORM ASD occluder was successfully deployed. On postprocedural day 3, transthoracic echocardiography showed mobile echogenic mass of 9 mm on the right side of the device. Intravenous heparin 10 IU/kg/hr was administrated continuously, and clopidogrel was added. On the following day, the mobile mass was not visible. Even though the occurrence rate of device thrombus is not high, device thrombosis can become a major complication of device closure of ASD because it may cause systemic and/or pulmonary embolism. Administration of dual antiplatelet therapy or other anticoagulant therapy should be considered if the patients have a higher risk of thrombosis. A 67-year-old female patient with rheumatoid arthritis that was well suppressed by medications except for steroids had catheter closure of the secundum atrial septal defect (ASD). After the administration of aspirin and intravenous heparin, a 32-mm of GORE® CARDIOFORM ASD occluder was successfully deployed. On postprocedural day 3, transthoracic echocardiography showed mobile echogenic mass of 9 mm on the right side of the device. Intravenous heparin 10 IU/kg/hr was administrated continuously, and clopidogrel was added. On the following day, the mobile mass was not visible. Even though the occurrence rate of device thrombus is not high, device thrombosis can become a major complication of device closure of ASD because it may cause systemic and/or pulmonary embolism. Administration of dual antiplatelet therapy or other anticoagulant therapy should be considered if the patients have a higher risk of thrombosis. A 67-year-old female patient with rheumatoid arthritis that was well suppressed by medications except for steroids had catheter closure of the secundum atrial septal defect (ASD). After the administration of aspirin and intravenous heparin, a 32-mm of GORE® CARDIOFORM ASD occluder was successfully deployed. On postprocedural day 3, transthoracic echocardiography showed mobile echogenic mass of 9 mm on the right side of the device. Intravenous heparin 10 IU/kg/hr was administrated continuously, and clopidogrel was added. On the following day, the mobile mass was not visible. Even though the occurrence rate of device thrombus is not high, device thrombosis can become a major complication of device closure of ASD because it may cause systemic and/or pulmonary embolism. Administration of dual antiplatelet therapy or other anticoagulant therapy should be considered if the patients have a higher risk of thrombosis.A 67-year-old female patient with rheumatoid arthritis that was well suppressed by medications except for steroids had catheter closure of the secundum atrial septal defect (ASD). After the administration of aspirin and intravenous heparin, a 32-mm of GORE® CARDIOFORM ASD occluder was successfully deployed. On postprocedural day 3, transthoracic echocardiography showed mobile echogenic mass of 9 mm on the right side of the device. Intravenous heparin 10 IU/kg/hr was administrated continuously, and clopidogrel was added. On the following day, the mobile mass was not visible. Even though the occurrence rate of device thrombus is not high, device thrombosis can become a major complication of device closure of ASD because it may cause systemic and/or pulmonary embolism. Administration of dual antiplatelet therapy or other anticoagulant therapy should be considered if the patients have a higher risk of thrombosis. |
| ArticleNumber | 100600 |
| Author | Shigemitsu, Yusuke Nakagawa, Naomi Okamoto, Kengo |
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| Cites_doi | 10.1007/s10067-014-2492-7 10.1136/annrheumdis-2013-203380 10.1002/ccd.31002 10.1002/ccd.30067 10.1016/0090-1229(92)90008-C 10.1136/annrheumdis-2020-218419 10.1016/j.jacc.2003.10.030 10.1002/ccd.24875 10.1002/ccd.28728 |
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| Keywords | Thrombus formation Atrial septal defect GORE cardioform ASD occluder Congenital heart disease Rheumatoid arthritis |
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| References_xml | – volume: 103 start-page: 741 year: 2024 Apr end-page: 750 ident: bib5 article-title: Right disc thrombosis of the new gore cardioform ASD occluder publication-title: Cathet Cardiovasc Interv – volume: 63 start-page: 155 year: 1992 end-page: 162 ident: bib8 article-title: Pathways of coagulation activation in situ in rheumatoid synovial tissue publication-title: Clin Immunol Immunopathol – volume: 33 start-page: 297 year: 2014 end-page: 304 ident: bib7 article-title: Risk of venous thromboembolism in patients with rheumatoid arthritis: a systematic review and meta-analysis publication-title: Clin Rheumatol – volume: 80 start-page: 169 year: 2021 end-page: 175 ident: bib10 article-title: Risk of venous thromboembolism in rheumatoid arthritis, and its association with disease activity: a nationwide cohort study from Sweden publication-title: Ann Rheum Dis – volume: 27 start-page: 846 year: 2009 end-page: 855 ident: bib9 article-title: Rheumatoid arthritis and thrombosis publication-title: Clin Exp Rheumatol – volume: 43 start-page: 302 year: 2004 end-page: 309 ident: bib2 article-title: Incidence and clinical course of thrombus formation on atrial septal defect and patient foramen ovale closure devices in 1,000 consecutive patients publication-title: J Am Coll Cardiol – volume: 82 start-page: 1123 year: 2013 end-page: 1138 ident: bib1 article-title: Short and long term complications of device closure of atrial septal defect and patent foramen ovale: meta-analysis of 28,142 patients from 203 studies publication-title: Cathet Cardiovasc Interv – volume: 99 start-page: 1161 year: 2022 end-page: 1164 ident: bib3 article-title: GORE Cardioform ASD device thrombus weeks after COVI-19 infection publication-title: Cathet Cardiovasc Interv – volume: 95 start-page: 1285 year: 2020 end-page: 1295 ident: bib4 article-title: ASSURED Investigators. ASSURED clinical study: new GORE® CARDIOFORM ASD occluder for transcatheter closure of atrial septal defect publication-title: Cathet Cardiovasc Interv – volume: 73 start-page: 1774 year: 2014 end-page: 1780 ident: bib6 article-title: Rheumatoid arthritis increases the risk of deep vein thrombosis and pulmonary thromboembolism: a nationwide cohort study publication-title: Ann Rheum Dis – volume: 33 start-page: 297 year: 2014 ident: 10.1016/j.ijcchd.2025.100600_bib7 article-title: Risk of venous thromboembolism in patients with rheumatoid arthritis: a systematic review and meta-analysis publication-title: Clin Rheumatol doi: 10.1007/s10067-014-2492-7 – volume: 27 start-page: 846 year: 2009 ident: 10.1016/j.ijcchd.2025.100600_bib9 article-title: Rheumatoid arthritis and thrombosis publication-title: Clin Exp Rheumatol – volume: 73 start-page: 1774 year: 2014 ident: 10.1016/j.ijcchd.2025.100600_bib6 article-title: Rheumatoid arthritis increases the risk of deep vein thrombosis and pulmonary thromboembolism: a nationwide cohort study publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2013-203380 – volume: 103 start-page: 741 issue: 5 year: 2024 ident: 10.1016/j.ijcchd.2025.100600_bib5 article-title: Right disc thrombosis of the new gore cardioform ASD occluder publication-title: Cathet Cardiovasc Interv doi: 10.1002/ccd.31002 – volume: 99 start-page: 1161 year: 2022 ident: 10.1016/j.ijcchd.2025.100600_bib3 article-title: GORE Cardioform ASD device thrombus weeks after COVI-19 infection publication-title: Cathet Cardiovasc Interv doi: 10.1002/ccd.30067 – volume: 63 start-page: 155 year: 1992 ident: 10.1016/j.ijcchd.2025.100600_bib8 article-title: Pathways of coagulation activation in situ in rheumatoid synovial tissue publication-title: Clin Immunol Immunopathol doi: 10.1016/0090-1229(92)90008-C – volume: 80 start-page: 169 year: 2021 ident: 10.1016/j.ijcchd.2025.100600_bib10 article-title: Risk of venous thromboembolism in rheumatoid arthritis, and its association with disease activity: a nationwide cohort study from Sweden publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2020-218419 – volume: 43 start-page: 302 year: 2004 ident: 10.1016/j.ijcchd.2025.100600_bib2 article-title: Incidence and clinical course of thrombus formation on atrial septal defect and patient foramen ovale closure devices in 1,000 consecutive patients publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2003.10.030 – volume: 82 start-page: 1123 year: 2013 ident: 10.1016/j.ijcchd.2025.100600_bib1 article-title: Short and long term complications of device closure of atrial septal defect and patent foramen ovale: meta-analysis of 28,142 patients from 203 studies publication-title: Cathet Cardiovasc Interv doi: 10.1002/ccd.24875 – volume: 95 start-page: 1285 year: 2020 ident: 10.1016/j.ijcchd.2025.100600_bib4 article-title: ASSURED Investigators. ASSURED clinical study: new GORE® CARDIOFORM ASD occluder for transcatheter closure of atrial septal defect publication-title: Cathet Cardiovasc Interv doi: 10.1002/ccd.28728 |
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| Snippet | A 67-year-old female patient with rheumatoid arthritis that was well suppressed by medications except for steroids had catheter closure of the secundum atrial... AbstractA 67-year-old female patient with rheumatoid arthritis that was well suppressed by medications except for steroids had catheter closure of the secundum... |
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| SubjectTerms | Atrial septal defect Cardiovascular Case Report Congenital heart disease GORE cardioform ASD occluder Rheumatoid arthritis Thrombus formation |
| Title | GORE® CARDIOFORM ASD occluder thrombus in a patient of rheumatoid arthritis occurred three days after deployment |
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