Patients with Coronary Artery Disease Have Lower Levels of Antibody to Heat-Stressed Fibroblast Derived Proteins, versus Normal Subjects

• Published in: Cardiovascular therapeutics Vol. 2021; pp. 1 - 9
• Main Authors: Aghamajidi, Azin, Khameneh, Hesam Babaei, Amirjamshidi, Narges, Jalali, Seyed Farzad, Akhavan-Niaki, Haleh, Khafri, Soraya, Mousavi, Seyedeh Narges, Golpour, Monireh, Mehri, Maryam, AmrollahMostafazadeh
• Format: Journal Article
• Language: English
• Published: London Hindawi 17.06.2021; John Wiley & Sons, Inc; Wiley
• Subjects: Analysis; Antibodies; Atherosclerosis; Cardiac stress tests; Cardiovascular disease; Cell culture; Coronary heart disease; Coronary vessels; Enzyme-linked immunosorbent assay; Ethylenediaminetetraacetic acid; Experiments; Fibroblasts; Flow cytometry; Health aspects; Heat shock proteins; Oxidative stress; Proteins; Tumor necrosis factor-TNF; Viral antibodies; United States > US; China; Germany

Cellular stress response plays an important role in the pathophysiology of coronary artery disease (CAD). Inhibition of cellular stress may provide a novel clinical approach regarding the diagnosis and treatment of CAD. Fibroblasts constitute 60-70% of cardiac cells and have a crucial role in cardio...