Folded biomimetic oligomers for enantioselective catalysis

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 106; no. 33; pp. 13679 - 13684
• Main Authors: Maayan, Galia, Ward, Michael D, Kirshenbaum, Kent
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 18.08.2009; National Acad Sciences
• Subjects: Active sites; Alcohols; Benzyl Alcohols - chemistry; Biochemistry; Biomimetics; Biopolymers; Catalysis; Catalysts; Chromatography, Gas - methods; Circular Dichroism; Cyclic N-Oxides - chemistry; Deoxyribonucleic acid; DNA; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Oligomers; Oxidation; Oxygen - chemistry; Peptides - chemistry; Physical Sciences; Protein Structure, Tertiary; Proteins; Reaction kinetics; Resins; Ribonucleic acid; RNA; Scaffolds; Solvents; Stereoisomerism; Temperature

Many naturally occurring biopolymers (i.e., proteins, RNA, DNA) owe their unique properties to their well-defined three-dimensional structures. These attributes have inspired the design and synthesis of folded architectures with functions ranging from molecular recognition to asymmetric catalysis. A...