Docetaxel induces Bcl-2- and pro-apoptotic caspase-independent death of human prostate cancer DU145 cells - OGURA, TAKEHARU; TANAKA, YOSHIYUKI; TAMAKI, HIROKI; HARADA, MAMORU (International journal of oncology, 2016)
Keywords: Androgens; Animals; Antineoplastic Agents - pharmacology; Apoptosis; Apoptosis - drug effects; Apoptosis - physiology; Bcl-2; Cancer therapies; caspase; Caspases - biosynthesis; Cell Line, Tumor; Cytochrome; cytotoxicity; Docetaxel; Drug Screening Assays, Antitumor; Drug therapy; Drugs; Experiments; Flow cytometry; Gene expression; Genetic aspects; Health aspects; Humans; Male; Mice; Mice, Inbred C3H; Mice, Nude; Patient outcomes; Prostate cancer; Prostatic Neoplasms - drug therapy; Prostatic Neoplasms - genetics; Prostatic Neoplasms - metabolism; Prostatic Neoplasms - pathology; Proteins; Proto-Oncogene Proteins c-bcl-2 - biosynthesis; Proto-Oncogene Proteins c-bcl-2 - genetics; Taxoids - pharmacology; Transfection; Tumor necrosis factor-TNF; Tumor suppressor genes; Xenograft Model Antitumor Assays; United States--US; Japan