Evaluation of fiber bundles across subjects through brain mapping and registration of diffusion tensor data

• Published in: NeuroImage (Orlando, Fla.) Vol. 54; pp. S165 - S175
• Main Authors: Pai, Darshan, Soltanian-Zadeh, Hamid, Hua, Jing
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 2011; Elsevier Limited
• Subjects: Accuracy; Adult; Algorithms; Analysis of fiber bundles; Anatomy & physiology; Anisotropy; Brain - anatomy & histology; Brain Mapping - methods; Brain research; Diffusion; Diffusion imaging; Diffusion Tensor Imaging - methods; Epilepsy; Epilepsy, Temporal Lobe - pathology; Female; Geometry; Humans; Hypotheses; Hypothesis testing; Image Interpretation, Computer-Assisted - methods; Male; Medical image processing; Methods; Multimodality fusion; Neural Pathways - anatomy & histology; Shape analysis; Standard deviation; Statistical analysis; Studies; Medical image processing; Diffusion imaging; Multimodality fusion; Shape analysis; Analysis of fiber bundles; Epilepsy

This paper presents a visualization and analysis framework for evaluating changes in structural organization of fiber bundles in human brain white matter. Statistical analysis of fiber bundle organization is conducted using an anisotropy measure, volume ratio (VR), which is ratio of anisotropic and...