Chemotherapy-Induced Peripheral Neuropathy Impairs Tertiary Dentine Formation: An In Vivo Study

• Published in: International dental journal Vol. 75; no. 5; p. 100899
• Main Authors: He, Jun, Zhan, Chaoning, Lu, Yanli, Chen, Junyang, Yang, Xiaojun, Hou, Jin
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.10.2025; Elsevier
• Subjects: Calcitonin gene-related peptide; Dentistry; Paclitaxel; Peripheral neuropathy; Scientific Research Report; Tertiary dentine; Calcitonin gene-related peptide; Peripheral neuropathy; Paclitaxel; Tertiary dentine

Chemotherapy-induced peripheral neuropathy (CIPN) is a common and well-documented adverse effect of chemotherapy, primarily targeting sensory nerves. Sensory nerves play a crucial role in the repair of dentine-pulp complex injuries. Despite this, the influence of CIPN on the repair processes of the...