Topographic staging of tau positron emission tomography images

• Published in: Alzheimer's & dementia : diagnosis, assessment & disease monitoring Vol. 10; no. 1; pp. 221 - 231
• Main Authors: Schwarz, Adam J., Shcherbinin, Sergey, Slieker, Lawrence J., Risacher, Shannon L., Charil, Arnaud, Irizarry, Michael C., Fleisher, Adam S., Southekal, Sudeepti, Joshi, Abhinay D., Devous, Michael D., Miller, Bradley B., Saykin, Andrew J.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 2018; Elsevier; Wiley
• Subjects: Alzheimer; AV-1451; Braak; Classification; Flortaucipir; PET; Special Section: State of the Field: Advances in Neuroimaging from the 2017 Alzheimer’s Imaging Consortium. (Guest Editors: Drs. David Wolk, Victor Villemagne & Bradford Dickerson); Stage; Staging; T807; Tau; AV-1451; Flortaucipir; Staging; Classification; Tau; Stage; Image; Braak; T807; Alzheimer; PET

It has been proposed that the signal distribution on tau positron emission tomography (PET) images could be used to define pathologic stages similar to those seen in neuropathology. Three topographic staging schemes for tau PET, two sampling the temporal and occipital subregions only and one samplin...