Comparisons of clustered regularly interspaced short palindromic repeats and viromes in human saliva reveal bacterial adaptations to salivary viruses

• Published in: Environmental microbiology Vol. 14; no. 9; pp. 2564 - 2576
• Main Authors: Pride, David T., Salzman, Julia, Relman, David A.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.09.2012
• Subjects: Bacteria; community structure; Ecosystem; ecosystems; genetics; Humans; immunity; Inverted Repeat Sequences; Inverted Repeat Sequences - genetics; Metagenome; Metagenome - genetics; microbial communities; microbiology; saliva; Saliva - microbiology; Saliva - virology; Streptococcus; Streptococcus - genetics; Streptococcus - virology; vertebrate viruses; virology; Viruses; Viruses - genetics

Summary Explorations of human microbiota have provided substantial insight into microbial community composition; however, little is known about interactions between various microbial components in human ecosystems. In response to the powerful impact of viral predation, bacteria have acquired potent...