Transcriptomics analysis for the identification of potential age-related genes and cells associated with three major urogenital cancers

• Published in: Scientific reports Vol. 11; no. 1; pp. 641 - 13
• Main Authors: Cao, Jinlong, Li, Jianpeng, Yang, Xin, Li, Pan, Yao, Zhiqiang, Han, Dali, Ying, Lijun, Wang, Lijie, Tian, Junqiang
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 12.01.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/114; 631/67; 692/4025; 692/4028; 692/53; Age; Age Factors; Aged; Aging; Bioinformatics; Biomarkers, Tumor - genetics; Bladder cancer; Cancer; Computational Biology; Female; Gene Expression Regulation, Neoplastic; Genital cancers; Genomes; Geriatrics; Humanities and Social Sciences; Humans; Kidney cancer; Kidney Neoplasms - genetics; Kidney Neoplasms - pathology; Male; Metastases; Middle Aged; multidisciplinary; Prognosis; Prostate cancer; Prostatic Neoplasms - genetics; Prostatic Neoplasms - pathology; Protein Interaction Maps; Renal cell carcinoma; Risk factors; Science; Science (multidisciplinary); Survival Rate; Transcriptome; Tumor Microenvironment; Tumors; Urinary Bladder Neoplasms - genetics; Urinary Bladder Neoplasms - pathology

Age is one of the most important risk factors of the occurrence for tumor patients. The majority of patients with urogenital cancers are the elderly, whose clinical characteristics are greatly affected by age and ageing. Our study aimed to explore age-related genes, cells, and biological changes in...