Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature

• Published in: Regenerative therapy Vol. 21; pp. 527 - 539
• Main Authors: Shimizu, Yusuke, Ntege, Edward Hosea, Sunami, Hiroshi, Inoue, Yoshikazu
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.12.2022; Japanese Society for Regenerative Medicine; Elsevier
• Subjects: Alopecia; Hair follicle regeneration; Hair loss; Hair regrowth; Review; Stem cell extracellular vesicles; Stem cell therapy; ADSVCs; LS; Hair regrowth; GVHD; Stem cell therapy; Hair follicle regeneration; SLE; TNF; PRP; MSCs; Th; EMA; AA; EMI; SCs; IL; AE; FGF; BM-MSCs; PMD-Act; GMP; iPSC-MSCs; MMP; Alopecia; ISSCR; ROS; AD-MSCs; SVF; FDA; MPHL; TTM; PI3K/Akt; Stem cell extracellular vesicles; DHT; iPSCs; MCP1; MAPK/ERK; TGF-β; AGA; Wnt; hDPCs; non-CA; CA; CD; EVs; OS; EGF; VEGF; Treg; IGF; CM; ADRCs; KGF; TA; ECM; FPHL; SALT; TE; HFSCs; hUC-MSCs; AA-PRP; LA; PDGF; PG; Hair loss; HF

Hair loss, or alopecia, is associated with several psychosocial and medical comorbidities, and it remains an economic burden to individuals and the society. Alopecia is attributable to varied mechanisms and features a multifactorial predisposition, and the available conventional medical intervention...