The Ameliorative Effects of Fucoidan in Thioacetaide-Induced Liver Injury in Mice

• Published in: Molecules Vol. 26; no. 7; p. 1937
• Main Authors: Tsai, Ming-Yang, Yang, Wei-Cheng, Lin, Chuen-Fu, Wang, Chao-Min, Liu, Hsien-Yueh, Lin, Chen-Si, Lin, Jen-Wei, Lin, Wei-Li, Lin, Tzu-Chun, Fan, Pei-Shan, Hung, Kuo-Hsiang, Lu, Yu-Wen, Chang, Geng-Ruei
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 30.03.2021; MDPI
• Subjects: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Biomarkers; Cancer; Chemical and Drug Induced Liver Injury, Chronic; Cytokines; Efficiency; Enzymes; Food; fucoidan; Inflammation; Injuries; Liver; Male; mice; Mice, Inbred C57BL; Organic chemistry; Oxidative Stress; Polysaccharides; QD241-441; thioacetamide; Tumor necrosis factor-TNF; Vascular endothelial growth factor; Veins & arteries; thioacetamide; inflammation; liver; fucoidan; mice

Liver disorders have been recognized as one major health concern. Fucoidan, a sulfated polysaccharide extracted from the brown seaweed Fucus serratus, has previously been reported as an anti-inflammatory and antioxidant. However, the discovery and validation of its hepatoprotective properties and el...