The interferon landscape along the respiratory tract impacts the severity of COVID-19 - Sposito, Benedetta; Broggi, Achille; Pandolfi, Laura; Crotta, Stefania; Clementi, Nicola; Ferrarese, Roberto; Sisti, Sofia; Criscuolo, Elena; Spreafico, Roberto; Long, Jaclyn M.; Ambrosi, Alessandro; Liu, Enju; et al. (Cell, 2021)
Keywords: Age Factors; Aging - pathology; airways; apoptosis; COVID-19; COVID-19 - genetics; COVID-19 - immunology; COVID-19 - pathology; COVID-19 infection; dendritic cell; epithelial cell; Epithelial Cells - pathology; Epithelial Cells - virology; Gene Expression Regulation; genes; Humans; interferon; interferons; Interferons - genetics; Interferons - metabolism; landscapes; Leukocytes - pathology; Leukocytes - virology; Life Sciences; lung; Lung - pathology; Lung - virology; lungs; pattern recognition receptor; Respiratory Distress Syndrome - pathology; Respiratory Distress Syndrome - virology; Respiratory System - virology; risk; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Severity of Illness Index; Type I IFN; Type III IFN; Viral Load; COVID-19; lung; Type III IFN; SARS-CoV-2; airways; interferon; epithelial cell; Type I IFN; dendritic cell; pattern recognition receptor