The Role of the Autonomic Nervous System in the Regulation of Aortic Stiffness

• Published in: Hypertension (Dallas, Tex. 1979) Vol. 68; no. 5; pp. 1290 - 1297
• Main Authors: Mäki-Petäjä, Kaisa M., Barrett, Sharon M.L., Evans, Sarah V., Cheriyan, Joseph, McEniery, Carmel M., Wilkinson, Ian B.
• Format: Journal Article
• Language: English
• Published: United States American Heart Association, Inc 01.11.2016; Lippincott, Williams & Wilkins
• Subjects: Adult; Arterial Pressure - physiology; Autonomic Nervous System - physiopathology; Cross-Over Studies; Cross-Sectional Studies; Double-Blind Method; Female; Hand Strength - physiology; Healthy Volunteers; Heart Rate - drug effects; Heart Rate - physiology; Hemodynamics - physiology; Humans; Hypertension - physiopathology; Male; Original; Pentolinium Tartrate - administration & dosage; Prognosis; Pulse Wave Analysis; Role; Vascular Stiffness - drug effects; Vascular Stiffness - physiology; Young Adult; blood pressure; heart rate; aortic stiffness; autonomic nervous system; hemodynamics; healthy volunteers

The autonomic nervous system is important in regulating blood pressure, but whether it regulates aortic stiffness is more contentious. We conducted 3 studies in young, healthy individuals to address this important question. Study 1 was a cross-sectional study of 347 subjects with detailed measuremen...