Inversion of pheromone preference optimizes foraging in C. elegans

Foraging animals have to locate food sources that are usually patchily distributed and subject to competition. Deciding when to leave a food patch is challenging and requires the animal to integrate information about food availability with cues signaling the presence of other individuals (e.g., pher...

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Published ineLife Vol. 10
Main Authors Dal Bello, Martina, Pérez-Escudero, Alfonso, Schroeder, Frank C, Gore, Jeff
Format Journal Article
LanguageEnglish
Published Cambridge eLife Science Publications, Ltd 06.07.2021
eLife Sciences Publications Ltd
eLife Sciences Publication
eLife Sciences Publications, Ltd
Subjects
Analysis
Animal behavior
Animals
Associative learning
behavioral plasticity
Ecology
Experiments
Food
Food availability
Food intake
Food sources
Foraging behavior
Information processing
Life Sciences
optimal foraging
pheromone valence
Pheromones
Preferences
Solvents
Success
Worms
Young adults
Canada
United States > US
Schulenburg Texas
Online AccessGet full text
ISSN2050-084X
2050-084X
DOI10.7554/eLife.58144

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Abstract Foraging animals have to locate food sources that are usually patchily distributed and subject to competition. Deciding when to leave a food patch is challenging and requires the animal to integrate information about food availability with cues signaling the presence of other individuals (e.g., pheromones). To study how social information transmitted via pheromones can aid foraging decisions, we investigated the behavioral responses of the model animal Caenorhabditis elegans to food depletion and pheromone accumulation in food patches. We experimentally show that animals consuming a food patch leave it at different times and that the leaving time affects the animal preference for its pheromones. In particular, worms leaving early are attracted to their pheromones, while worms leaving later are repelled by them. We further demonstrate that the inversion from attraction to repulsion depends on associative learning and, by implementing a simple model, we highlight that it is an adaptive solution to optimize food intake during foraging.
AbstractList Foraging animals have to locate food sources that are usually patchily distributed and subject to competition. Deciding when to leave a food patch is challenging and requires the animal to integrate information about food availability with cues signaling the presence of other individuals (e.g., pheromones). To study how social information transmitted via pheromones can aid foraging decisions, we investigated the behavioral responses of the model animal Caenorhabditis elegans to food depletion and pheromone accumulation in food patches. We experimentally show that animals consuming a food patch leave it at different times and that the leaving time affects the animal preference for its pheromones. In particular, worms leaving early are attracted to their pheromones, while worms leaving later are repelled by them. We further demonstrate that the inversion from attraction to repulsion depends on associative learning and, by implementing a simple model, we highlight that it is an adaptive solution to optimize food intake during foraging.
Foraging animals have to locate food sources that are usually patchily distributed and subject to competition. Deciding when to leave a food patch is challenging and requires the animal to integrate information about food availability with cues signaling the presence of other individuals (e.g., pheromones). To study how social information transmitted via pheromones can aid foraging decisions, we investigated the behavioral responses of the model animal Caenorhabditis elegans to food depletion and pheromone accumulation in food patches. We experimentally show that animals consuming a food patch leave it at different times and that the leaving time affects the animal preference for its pheromones. In particular, worms leaving early are attracted to their pheromones, while worms leaving later are repelled by them. We further demonstrate that the inversion from attraction to repulsion depends on associative learning and, by implementing a simple model, we highlight that it is an adaptive solution to optimize food intake during foraging.
Foraging animals have to locate food sources that are usually patchily distributed and subject to competition. Deciding when to leave a food patch is challenging and requires the animal to integrate information about food availability with cues signaling the presence of other individuals (e.g., pheromones). To study how social information transmitted via pheromones can aid foraging decisions, we investigated the behavioral responses of the model animal Caenorhabditis elegans to food depletion and pheromone accumulation in food patches. We experimentally show that animals consuming a food patch leave it at different times and that the leaving time affects the animal preference for its pheromones. In particular, worms leaving early are attracted to their pheromones, while worms leaving later are repelled by them. We further demonstrate that the inversion from attraction to repulsion depends on associative learning and, by implementing a simple model, we highlight that it is an adaptive solution to optimize food intake during foraging.Foraging animals have to locate food sources that are usually patchily distributed and subject to competition. Deciding when to leave a food patch is challenging and requires the animal to integrate information about food availability with cues signaling the presence of other individuals (e.g., pheromones). To study how social information transmitted via pheromones can aid foraging decisions, we investigated the behavioral responses of the model animal Caenorhabditis elegans to food depletion and pheromone accumulation in food patches. We experimentally show that animals consuming a food patch leave it at different times and that the leaving time affects the animal preference for its pheromones. In particular, worms leaving early are attracted to their pheromones, while worms leaving later are repelled by them. We further demonstrate that the inversion from attraction to repulsion depends on associative learning and, by implementing a simple model, we highlight that it is an adaptive solution to optimize food intake during foraging.
Audience Academic
Author Dal Bello, Martina
Schroeder, Frank C
Gore, Jeff
Pérez-Escudero, Alfonso
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  givenname: Frank C
  orcidid: 0000-0002-4420-0237
  surname: Schroeder
  fullname: Schroeder, Frank C
  organization: Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University, New York, United States
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  givenname: Jeff
  orcidid: 0000-0003-4583-8555
  surname: Gore
  fullname: Gore, Jeff
  organization: Physics of Living Systems Group, Department of Physics, Massachusetts Institute of Technology, Cambridge, United States
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Snippet Foraging animals have to locate food sources that are usually patchily distributed and subject to competition. Deciding when to leave a food patch is...
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SubjectTerms Analysis
Animal behavior
Animals
Associative learning
behavioral plasticity
Ecology
Experiments
Food
Food availability
Food intake
Food sources
Foraging behavior
Information processing
Life Sciences
optimal foraging
pheromone valence
Pheromones
Preferences
Solvents
Success
Worms
Young adults
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Title Inversion of pheromone preference optimizes foraging in C. elegans
URI https://www.proquest.com/docview/2595207351
https://www.proquest.com/docview/2548906584
https://hal.science/hal-03424088
https://pubmed.ncbi.nlm.nih.gov/PMC8260229
https://doaj.org/article/562a921d7db04fb4a193d08c0f1eed0e
Volume 10
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