Pro-inflammatory cytokine associated with somatic and pain symptoms in depression

• Published in: Journal of affective disorders Vol. 155; pp. 28 - 34
• Main Authors: Bai, Ya-Mei, Chiou, Wen-Fei, Su, Tung-Ping, Li, Cheng-Ta, Chen, Mu-Hong
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier B.V 01.02.2014; Elsevier
• Subjects: Adiponectin - adverse effects; Adiponectin - analysis; Adult; Adult and adolescent clinical studies; Biological and medical sciences; Body Mass Index; C-Reactive Protein - adverse effects; C-Reactive Protein - analysis; Case-Control Studies; Chemokine CCL2 - adverse effects; Chemokine CCL2 - analysis; Cytokines - adverse effects; Cytokines - analysis; Depression; Depression - blood; Depression - epidemiology; Depression - immunology; Depressive personality disorders; Enzyme-Linked Immunosorbent Assay; Female; Gender; Humans; Male; Medical sciences; Middle Aged; Miscellaneous; Mood disorders; P-Selectin - adverse effects; P-Selectin - analysis; Pain; Pain - blood; Pain - epidemiology; Pain - immunology; Pro-inflammatory cytokines; Psychiatric Status Rating Scales; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Receptors, Interleukin-2 - analysis; Receptors, Interleukin-6 - analysis; Receptors, Tumor Necrosis Factor - analysis; Severity of Illness Index; Somatic and pain symptoms; Somatic symptoms; Somatoform Disorders - blood; Somatoform Disorders - epidemiology; Somatoform Disorders - immunology; Pro-inflammatory cytokines; Depression; Somatic and pain symptoms; Mood disorder; Symptomatology; Pain; Cytokine; Inflammation

More than two-thirds of depressed patients complain of somatic and pain symptoms, which are frequently regarded as a psychological reaction. Although there is a growing body of evidence showing that depression is related to immune abnormalities, few studies have investigated the association between...