Comparison of two different methods of image analysis for the assessment of microglial activation in patients with multiple sclerosis using (R)-[N-methyl-carbon-11]PK11195 - Kang, Yeona; Schlyer, David; Kaunzner, Ulrike W.; Kuceyeski, Amy; Kothari, Paresh J.; Gauthier, Susan A. (PloS one, 2018)
Keywords: 60 APPLIED LIFE SCIENCES; Activation analysis; Adult; Binding; Binding sites; Biology and Life Sciences; Brain; Brain - cytology; Brain - diagnostic imaging; Brain - pathology; Care and treatment; Central nervous system; Cluster analysis; Clustering; Comparative analysis; Cortex; Female; Graphical methods; Human subjects; Humans; Image analysis; Image processing; Image Processing, Computer-Assisted - methods; Immune response; Immune system; Innate immunity; Isoquinolines - administration & dosage; Isoquinolines - chemistry; Lesions; Macrophages; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Masks; Medical imaging; Medicine and Health Sciences; Methods; Microglia; Microglia - immunology; Microglia - pathology; Middle Aged; Multiple sclerosis; Multiple Sclerosis, Chronic Progressive - diagnostic imaging; Multiple Sclerosis, Chronic Progressive - immunology; Multiple Sclerosis, Chronic Progressive - pathology; Neuroimaging; Nuclear medicine; Patients; Physical Sciences; Positron emission; Positron emission tomography; Positron-Emission Tomography - methods; Radiopharmaceuticals - administration & dosage; Radiopharmaceuticals - chemistry; Reproducibility of Results; Research and Analysis Methods; Science & Technology - Other Topics; Substantia alba; Substantia grisea; Thalamus; Therapeutic applications; Tomography; New York; United States--US