Gabapentinoids Are Effective in Decreasing Neuropathic Pain and Other Secondary Outcomes After Spinal Cord Injury: A Meta-Analysis

• Published in: Archives of physical medicine and rehabilitation Vol. 95; no. 11; pp. 2180 - 2186
• Main Authors: Mehta, Swati, McIntyre, Amanda, Dijkers, Marcel, Loh, Eldon, Teasell, Robert W.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2014
• Subjects: Amines - adverse effects; Amines - therapeutic use; Analgesics - adverse effects; Analgesics - therapeutic use; Anxiety - etiology; Clinical Trials as Topic; Cyclohexanecarboxylic Acids - adverse effects; Cyclohexanecarboxylic Acids - therapeutic use; Depression - etiology; gamma-Aminobutyric Acid - adverse effects; gamma-Aminobutyric Acid - analogs & derivatives; gamma-Aminobutyric Acid - therapeutic use; Humans; Neuralgia - drug therapy; Neuralgia - etiology; Pain; Physical Medicine and Rehabilitation; Pregabalin; Rehabilitation; Sleep Disorders, Intrinsic - etiology; Spinal cord injuries; Spinal Cord Injuries - complications; RR; RCT; Pain; CI; SCI; Spinal cord injuries; Rehabilitation; SMD; spinal cord injury; standardized mean difference; risk ratio; randomized controlled trial; confidence interval

To examine the effectiveness of gabapentin and pregabalin in diminishing neuropathic pain and other secondary conditions in individuals with spinal cord injury (SCI). A systematic search was conducted using multiple databases for relevant articles published from 1980 to June 2013. Controlled and unc...