Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth - Lin, Ruiting; Tao, Ren; Gao, Xue; Li, Tingting; Zhou, Xin; Guan, Kun-Liang; Xiong, Yue; Lei, Qun-Ying (Molecular cell, 2013)
Keywords: Acetylation; Animals; ATP Citrate (pro-S)-Lyase - chemistry; ATP Citrate (pro-S)-Lyase - genetics; ATP Citrate (pro-S)-Lyase - metabolism; biosynthesis; Blotting, Western; Calmodulin-Binding Proteins - genetics; Calmodulin-Binding Proteins - metabolism; cell growth; Cell Proliferation; Cytoskeletal Proteins - genetics; Cytoskeletal Proteins - metabolism; fatty acids; Fatty Acids - metabolism; glucose; Humans; Immunoenzyme Techniques; lung neoplasms; Lung Neoplasms - genetics; Lung Neoplasms - metabolism; Lung Neoplasms - pathology; lysine; Male; Mice; Mice, Nude; neoplasm cells; p300-CBP Transcription Factors - genetics; p300-CBP Transcription Factors - metabolism; Proteasome Endopeptidase Complex - metabolism; Protein Processing, Post-Translational; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger - genetics; Sirtuin 2 - genetics; Sirtuin 2 - metabolism; Tumor Cells, Cultured; Ubiquitin - metabolism; Ubiquitination