Ketamine blocks bursting in the lateral habenula to rapidly relieve depression - Yang, Yan; Cui, Yihui; Sang, Kangning; Dong, Yiyan; Ni, Zheyi; Ma, Shuangshuang; Hu, Hailan (Nature (London), 2018)
Keywords: 13; 42/41; 631/378/1457; 631/378/1689/1414; 631/378/2586; 64; 64/60; 64/86; 9/30; 9/74; Action Potentials - drug effects; Affect - drug effects; Anhedonia - drug effects; Animal models; Animals; Antidepressants; Antidepressive Agents - administration & dosage; Antidepressive Agents - pharmacology; Antidepressive Agents - therapeutic use; Bursting; Calcium Channel Blockers - pharmacology; Calcium Channel Blockers - therapeutic use; Calcium channels; Calcium channels (T-type); Calcium channels (voltage-gated); Calcium Channels - metabolism; Depression (Mood disorder); Depression - drug therapy; Disease Models, Animal; Firing pattern; Glutamate receptors; Habenula; Habenula - drug effects; Habenula - metabolism; Habenula - pathology; Habenula - radiation effects; Hedonic response; Humanities and Social Sciences; Ketamine; Ketamine - administration & dosage; Ketamine - pharmacology; Ketamine - therapeutic use; Luteinizing hormone; Male; Mental depression; Mental disorders; Mental health; Mice; Mood; multidisciplinary; N-Methyl-D-aspartic acid receptors; Neurons; Neurons - drug effects; Neurons - metabolism; Pharmacology; Physiological aspects; Pineal gland; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors; Receptors, N-Methyl-D-Aspartate - metabolism; Reinforcement; Reward; Rodents; Science; Synchronism; Synchronization; Theta Rhythm - drug effects