Genetic characterization of a novel recombinant echovirus 30 strain causing a regional epidemic of aseptic meningitis in Hokkaido, Japan, 2017

• Published in: Archives of Virology Vol. 165; no. 2; pp. 433 - 438
• Main Authors: Miyoshi, Masahiro, Goto, Akiko, Komagome, Rika, Yamaguchi, Hiroki, Maruo, Yuji, Nakanishi, Masanori, Ishida, Setsuko, Nagano, Hideki, Sugisawa, Takahisa, Okano, Motohiko
• Format: Journal Article
• Language: English
• Published: Austria Springer Science and Business Media LLC 01.02.2020; Springer Nature B.V; Springer Vienna
• Subjects: Amino acids; Aseptic meningitis; Brief Report; Capsid protein; Capsid Proteins; Capsid Proteins - genetics; coat proteins; Disease Outbreaks; DNA-directed RNA polymerase; Echovirus Infections; Echovirus Infections - virology; Enterovirus B, Human; Enterovirus B, Human - genetics; Enterovirus Infections; Enterovirus Infections - virology; Enteroviruses; Epidemics; France; Genes; Genomes; genomics; Genotype; Germany; Human enterovirus; Humans; Japan; Meningitis; Meningitis, Aseptic; Meningitis, Aseptic - virology; Molecular Epidemiology; Molecular Epidemiology - methods; Phylogenetics; Phylogeny; proteinases; Public health; Recombination; RNA polymerase; RNA, Viral; RNA, Viral - genetics; RNA-directed RNA polymerase; Russia; Sequence Analysis, DNA; Sequence Analysis, DNA - methods; Switzerland; United Kingdom; virology; United Kingdom; France; Switzerland; Japan; Germany; Russia; Aseptic meningitis; Genetic characterization; Outbreak; Genome recombination; Echovirus 30

A regional epidemic of aseptic meningitis caused by echovirus 30 (E30) occurred in Hokkaido, Japan, during the period of August-December 2017. To investigate their phylogenetic relationship to other human enteroviruses, we determined the complete genomic nucleotide sequences of isolates from this ou...