Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis - Moore, Wendy C.; Hastie, Annette T.; Li, Xingnan; Li, Huashi; Busse, William W.; Jarjour, Nizar N.; Wenzel, Sally E.; Peters, Stephen P.; Meyers, Deborah A.; Bleecker, Eugene R. (Journal of allergy and clinical immunology, 2014)
Keywords: Adolescent; Adult; Age; Age Factors; Allergy and Immunology; Asthma; Asthma - blood; Asthma - diagnosis; Asthma - physiopathology; Biological and medical sciences; Body mass index; Cluster Analysis; Colleges & universities; Discriminant analysis; eosinophils; Family medical history; Female; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Granulocytes; Humans; Immunopathology; Leukocyte Count; Male; Medical sciences; Middle Aged; Multivariate analysis; Neutrophils; Phenotype; Respiratory Function Tests; Risk Factors; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; severe asthma; Severe Asthma Research Program; Severity of Illness Index; sputum; Sputum - cytology; Statistical methods; Young Adult; phenotype; ATS; eosinophils; sputum; SARP; Severe Asthma Research Program; FVC; severe asthma; ICS; HCU; cluster analysis; neutrophils; OCS; BMI; Forced vital capacity; Inhaled corticosteroid; Oral corticosteroid; American Thoracic Society; Body mass index; Health care utilization; Immunopathology; Granulocyte; Eosinophil; Numeration; Phenotype; Association; Immunology; Research program; Sputum; Neutrophil; Severe asthma