Neurochemical and BOLD Responses during Neuronal Activation Measured in the Human Visual Cortex at 7 Tesla

• Published in: Journal of cerebral blood flow and metabolism Vol. 35; no. 4; pp. 601 - 610
• Main Authors: Bednařík, Petr, Tkáč, Ivan, Giove, Federico, DiNuzzo, Mauro, Deelchand, Dinesh K, Emir, Uzay E, Eberly, Lynn E, Mangia, Silvia
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 07.01.2015; Sage Publications Ltd; Nature Publishing Group
• Subjects: Adult; Female; gamma-Aminobutyric Acid - metabolism; Glucose - metabolism; Glutamic Acid - metabolism; Humans; Lactic Acid - metabolism; Magnetic Resonance Imaging; Male; Middle Aged; Original; Oxygen - blood; Photic Stimulation; Visual Cortex - physiology; Young Adult; Neurochemistry; Visual Stimulation; Functional Spectroscopy; GABA quantification

Several laboratories have consistently reported small concentration changes in lactate, glutamate, aspartate, and glucose in the human cortex during prolonged stimuli. However, whether such changes correlate with blood oxygenation level—dependent functional magnetic resonance imaging (BOLD-fMRI) sig...