Multicomponent Diene-Transmissive Diels-Alder Sequences Featuring Aminodendralenes

• Published in: Angewandte Chemie International Edition Vol. 55; no. 9; pp. 3081 - 3085
• Main Authors: Tan, Siu Min, Willis, Anthony C., Paddon-Row, Michael N., Sherburn, Michael S.
• Format: Journal Article
• Language: English
• Published: WEINHEIM Blackwell Publishing Ltd 24.02.2016; Wiley; Wiley Subscription Services, Inc
• Edition: International ed. in English
• Subjects: Ambient temperature; Chemical bonds; Chemistry; Chemistry, Multidisciplinary; Density; density functional calculations; Density functional theory; Diels-Alder reactions; domino reactions; Functional anatomy; Mathematical analysis; multicomponent reactions; Physical Sciences; polycycles; Science & Technology; Temperature effects; Diels-Alder reactions; density functional calculations; multicomponent reactions; CATALYSIS; domino reactions; CYCLOADDITIONS; REMOTE FUNCTIONALIZATION; ORGANOCATALYSIS; ENAMINES; polycycles

1‐Aminodecalins were prepared from acyclic precursors by combining the powerful twofold diene‐transmissive Diels–Alder chemistry of [3]dendralenes with the simplicity of enamine formation. On mixing at ambient temperature, a simple dienal condenses with a primary or secondary amine to generate the e...