MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis - Pichiorri, Flavia; Suh, Sung-Suk; Ladetto, Marco; Kuehl, Michael; Palumbo, Tiziana; Drandi, Daniela; Taccioli, Cristian; Zanesi, Nicola; Alder, Hansjuerg; Hagan, John P; Munker, Reinhold; Volinia, Stefano; et al. (Proceedings of the National Academy of Sciences - PNAS, 2008)
Keywords: Animals; antagonists; Apoptosis Regulatory Proteins - metabolism; Base Sequence; Bcl-2-Like Protein 11; Biological Sciences; Bone marrow; Cell growth; Cell Line, Tumor; Cell lines; Cells; Gene expression; Gene Expression Profiling; gene expression regulation; Gene Expression Regulation, Neoplastic; genes; Genes, Neoplasm; Health; Humans; interleukin-6; Membrane Proteins - metabolism; messenger RNA; Mice; Mice, Nude; microarray technology; MicroRNA; MicroRNAs - genetics; MicroRNAs - metabolism; Molecular Sequence Data; Monoclonal Gammopathy of Undetermined Significance; Multiple myeloma; Multiple Myeloma - genetics; Multiple Myeloma - pathology; myeloma; non-coding RNA; Oligonucleotides; p300-CBP Transcription Factors - metabolism; pathogenesis; Pathology; Plasma cells; Plasma Cells - metabolism; Plasma Cells - pathology; proteins; Proto-Oncogene Proteins - metabolism; quantitative polymerase chain reaction; Receptors, Interleukin-6 - metabolism; Repressor Proteins - metabolism; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleic acid; RNA; Rodents; Signatures; STAT3 Transcription Factor - metabolism; Studies; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins - metabolism; Transfection; Tumor cell line; Tumor Suppressor Protein p53 - metabolism; Tumors; Up-Regulation