Dissociating behavioral disorders in early dementia—An FDG-PET study

• Published in: Psychiatry research. Neuroimaging Vol. 194; no. 3; pp. 235 - 244
• Main Authors: Schroeter, Matthias L., Vogt, Barbara, Frisch, Stefan, Becker, Georg, Seese, Anita, Barthel, Henryk, Mueller, Karsten, Villringer, Arno, Sabri, Osama
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier B.V 30.12.2011; Elsevier
• Subjects: Adult and adolescent clinical studies; Aged; Alzheimer's disease; Analysis of Variance; Apathy; Behavioral Symptoms - diagnostic imaging; Behavioral Symptoms - etiology; Biological and medical sciences; Brain - diagnostic imaging; Brain - pathology; Brain Mapping; Cognition Disorders - diagnostic imaging; Cognition Disorders - etiology; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Dementia - complications; Dementia - diagnostic imaging; Disinhibition; Eating disorders; Female; Fluorodeoxyglucose F18; Frontotemporal dementia; Humans; Male; Medical sciences; Middle Aged; Neurology; Neuropsychological Tests; Organic mental disorders. Neuropsychology; Positron-Emission Tomography - methods; Psychiatric Status Rating Scales; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Radiology; Regression Analysis; Semantic dementia; FDG-PET; Disinhibition; Semantic dementia; VTA; AD; MRI; NPI; FTLD; Eating disorders; MNI; BADS; CDR; Apathy; SD; SPM; MCI; ANOVA; FTD; FWHM; SCI; Frontotemporal dementia; Alzheimer's disease; BA; Statistical Parametric Mapping; Neuropsychiatric Inventory; Mild cognitive impairment; Behavioral Assessment of the Dysexecutive Syndrome; Ventral tegmental area; [ 18F] fluorodeoxyglucose positron emission tomography; Subjective cognitive impairment; Frontotemporal lobar degeneration; Brodmann area; Montreal Neurological Institute; Magnetic resonance imaging; Full width at half maximum; Clinical Dementia Rating Scale; Analysis of variance; Radionuclide study; Human; Nervous system diseases; 2-deoxy-2-fluoroglucose; Alzheimer disease; Eating disorder; Cerebral disorder; Behavioral disorder; Central nervous system disease; Early; Degenerative disease; Desinhibition; Positron emission tomography

Behavioral impairments occur frequently in dementia. Studies with magnetic resonance imaging, measuring atrophy, have systematically investigated their neural correlates. Such a systematic approach has not yet been applied to imaging with [18F] fluorodeoxyglucose positron emission tomography (FDG-PE...