Swept-Source Optical Coherence Tomographic Findings of Choroidal Osteoma

Purpose: To report the morphologic features of a choroidal osteoma using swept-source optical coherence tomography (SS-OCT) and fundus autofluorescence (FAF). Methods: Two eyes of two cases with a choroidal osteoma were studied using SS-OCT and FAF. Results: The location of the tumor was circumpapil...

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Published inCase Reports in Ophthalmology Vol. 5; no. 2; pp. 195 - 202
Main Authors Hayashi, Yuki, Mitamura, Yoshinori, Egawa, Mariko, Semba, Kentaro, Nagasawa, Toshihiko
Format Journal Article
LanguageEnglish
Published Basel, Switzerland S. Karger AG 05.07.2014
Karger Publishers
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Abstract Purpose: To report the morphologic features of a choroidal osteoma using swept-source optical coherence tomography (SS-OCT) and fundus autofluorescence (FAF). Methods: Two eyes of two cases with a choroidal osteoma were studied using SS-OCT and FAF. Results: The location of the tumor was circumpapillary without macular involvement in case 1 and juxtapapillary with macular involvement in case 2. Both cases had a mixture of calcified and decalcified areas, and a concomitant choroidal neovascularization was found in case 2. The FAF images showed decreased autofluorescence in the central decalcified regions and relatively preserved fluorescence in marginal calcified regions in both cases. SS-OCT revealed a normal inner retina and an abnormal outer retina in both cases, and subretinal fluid in case 2. The calcified regions appeared sponge-like and were multilayered in case 2. A lamellar reflective pattern was observed in the decalcified regions in case 1, and hyperreflective mound-like areas were observed in both cases. SS-OCT demonstrated hyperreflective areas above Bruch's membrane accompanied by disruption of Bruch's membrane in case 1. The chorioscleral border was visible in both cases. Conclusions: The FAF pattern in the calcified and decalcified areas of the choroidal osteoma may correspond to the different stage of tumor evolution. The SS-OCT findings indicate that choroidal osteomas can have characteristic reflective patterns and alterations of the overlying retina.
AbstractList To report the morphologic features of a choroidal osteoma using swept-source optical coherence tomography (SS-OCT) and fundus autofluorescence (FAF). Two eyes of two cases with a choroidal osteoma were studied using SS-OCT and FAF. The location of the tumor was circumpapillary without macular involvement in case 1 and juxtapapillary with macular involvement in case 2. Both cases had a mixture of calcified and decalcified areas, and a concomitant choroidal neovascularization was found in case 2. The FAF images showed decreased autofluorescence in the central decalcified regions and relatively preserved fluorescence in marginal calcified regions in both cases. SS-OCT revealed a normal inner retina and an abnormal outer retina in both cases, and subretinal fluid in case 2. The calcified regions appeared sponge-like and were multilayered in case 2. A lamellar reflective pattern was observed in the decalcified regions in case 1, and hyperreflective mound-like areas were observed in both cases. SS-OCT demonstrated hyperreflective areas above Bruch's membrane accompanied by disruption of Bruch's membrane in case 1. The chorioscleral border was visible in both cases. The FAF pattern in the calcified and decalcified areas of the choroidal osteoma may correspond to the different stage of tumor evolution. The SS-OCT findings indicate that choroidal osteomas can have characteristic reflective patterns and alterations of the overlying retina.
Purpose: To report the morphologic features of a choroidal osteoma using swept-source optical coherence tomography (SS-OCT) and fundus autofluorescence (FAF). Methods: Two eyes of two cases with a choroidal osteoma were studied using SS-OCT and FAF. Results: The location of the tumor was circumpapillary without macular involvement in case 1 and juxtapapillary with macular involvement in case 2. Both cases had a mixture of calcified and decalcified areas, and a concomitant choroidal neovascularization was found in case 2. The FAF images showed decreased autofluorescence in the central decalcified regions and relatively preserved fluorescence in marginal calcified regions in both cases. SS-OCT revealed a normal inner retina and an abnormal outer retina in both cases, and subretinal fluid in case 2. The calcified regions appeared sponge-like and were multilayered in case 2. A lamellar reflective pattern was observed in the decalcified regions in case 1, and hyperreflective mound-like areas were observed in both cases. SS-OCT demonstrated hyperreflective areas above Bruch's membrane accompanied by disruption of Bruch's membrane in case 1. The chorioscleral border was visible in both cases. Conclusions: The FAF pattern in the calcified and decalcified areas of the choroidal osteoma may correspond to the different stage of tumor evolution. The SS-OCT findings indicate that choroidal osteomas can have characteristic reflective patterns and alterations of the overlying retina.
To report the morphologic features of a choroidal osteoma using swept-source optical coherence tomography (SS-OCT) and fundus autofluorescence (FAF).PURPOSETo report the morphologic features of a choroidal osteoma using swept-source optical coherence tomography (SS-OCT) and fundus autofluorescence (FAF).Two eyes of two cases with a choroidal osteoma were studied using SS-OCT and FAF.METHODSTwo eyes of two cases with a choroidal osteoma were studied using SS-OCT and FAF.The location of the tumor was circumpapillary without macular involvement in case 1 and juxtapapillary with macular involvement in case 2. Both cases had a mixture of calcified and decalcified areas, and a concomitant choroidal neovascularization was found in case 2. The FAF images showed decreased autofluorescence in the central decalcified regions and relatively preserved fluorescence in marginal calcified regions in both cases. SS-OCT revealed a normal inner retina and an abnormal outer retina in both cases, and subretinal fluid in case 2. The calcified regions appeared sponge-like and were multilayered in case 2. A lamellar reflective pattern was observed in the decalcified regions in case 1, and hyperreflective mound-like areas were observed in both cases. SS-OCT demonstrated hyperreflective areas above Bruch's membrane accompanied by disruption of Bruch's membrane in case 1. The chorioscleral border was visible in both cases.RESULTSThe location of the tumor was circumpapillary without macular involvement in case 1 and juxtapapillary with macular involvement in case 2. Both cases had a mixture of calcified and decalcified areas, and a concomitant choroidal neovascularization was found in case 2. The FAF images showed decreased autofluorescence in the central decalcified regions and relatively preserved fluorescence in marginal calcified regions in both cases. SS-OCT revealed a normal inner retina and an abnormal outer retina in both cases, and subretinal fluid in case 2. The calcified regions appeared sponge-like and were multilayered in case 2. A lamellar reflective pattern was observed in the decalcified regions in case 1, and hyperreflective mound-like areas were observed in both cases. SS-OCT demonstrated hyperreflective areas above Bruch's membrane accompanied by disruption of Bruch's membrane in case 1. The chorioscleral border was visible in both cases.The FAF pattern in the calcified and decalcified areas of the choroidal osteoma may correspond to the different stage of tumor evolution. The SS-OCT findings indicate that choroidal osteomas can have characteristic reflective patterns and alterations of the overlying retina.CONCLUSIONSThe FAF pattern in the calcified and decalcified areas of the choroidal osteoma may correspond to the different stage of tumor evolution. The SS-OCT findings indicate that choroidal osteomas can have characteristic reflective patterns and alterations of the overlying retina.
Author Mitamura, Yoshinori
Egawa, Mariko
Nagasawa, Toshihiko
Semba, Kentaro
Hayashi, Yuki
AuthorAffiliation b Department of Ophthalmology, Saneikai Tsukazaki Hospital, Himeji, Japan
a Department of Ophthalmology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Himeji, Japan
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Cites_doi 10.1016/S0002-9394(01)01336-8
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Keywords Swept-source optical coherence tomography
Fundus autofluorescence
Choroidal osteoma
Language English
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References Nagasawa T, Mitamura Y, Katome T, Nagasato D, Tabuchi H: Swept-source optical coherence tomographic findings in morning glory syndrome. Retina 2014;34:206-208.2371940110.1097/IAE.0b013e318296575c
Nagasawa T, Mitamura Y, Katome T, Shinomiya K, Naito T, Nagasato D, Shimizu Y, Tabuchi H, Kiuchi Y: Macular choroidal thickness and volume in healthy pediatric individuals measured by swept-source optical coherence tomography. Invest Ophthalmol Vis Sci 2013;54:7068-7074.2410611410.1167/iovs.13-12350
Erol MK, Coban DT, Ceran BB, Bulut M: Enhanced depth imaging optical coherence tomography and fundus autofluorescence findings in bilateral choroidal osteoma: a case report. Arq Bras Oftalmol 2013;76:189-191.2392908210.1590/S0004-27492013000300012
Egawa M, Mitamura Y, Hayashi Y, Naito T: Spectral-domain optical coherence tomographic and fundus autofluorescence findings in eyes with primary intraocular lymphoma. Clin Ophthalmol 2014;8:335-341.2452019010.2147/OPTH.S58114
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– reference: Navajas EV, Costa RA, Calucci D, Hammoudi DS, Simpson ER, Altomare F: Multimodal fundus imaging in choroidal osteoma. Am J Ophthalmol 2012;153:890-895.2226515510.1016/j.ajo.2011.10.025
– reference: Pellegrini M, Invernizzi A, Giani A, Staurenghi G: Enhanced depth imaging optical coherence tomography features of choroidal osteoma. Retina 2013, Epub ahead of print.2426347010.1097/IAE.0000000000000017
– reference: Egawa M, Mitamura Y, Hayashi Y, Naito T: Spectral-domain optical coherence tomographic and fundus autofluorescence findings in eyes with primary intraocular lymphoma. Clin Ophthalmol 2014;8:335-341.2452019010.2147/OPTH.S58114
– reference: Alyward GW, Chang TS, Pautler SE, Gass JD: A long-term follow up of choroidal osteoma. Arch Ophthalmol 1998;116:1337-1341.979063310.1001/archopht.116.10.1337
– reference: Gass JD, Guerry RK, Jack RL, Harris G: Choroidal osteoma. Arch Ophthalmol 1978;96:428-435.62967910.1001/archopht.1978.03910050204002
– reference: Nagasawa T, Mitamura Y, Katome T, Shinomiya K, Naito T, Nagasato D, Shimizu Y, Tabuchi H, Kiuchi Y: Macular choroidal thickness and volume in healthy pediatric individuals measured by swept-source optical coherence tomography. Invest Ophthalmol Vis Sci 2013;54:7068-7074.2410611410.1167/iovs.13-12350
– reference: Fukasawa A, Iijima H: Optical coherence tomography of choroidal osteoma. Am J Ophthalmol 2002;133:419-421.1186098810.1016/S0002-9394(01)01336-8
– reference: Nagasawa T, Mitamura Y, Katome T, Nagasato D, Tabuchi H: Swept-source optical coherence tomographic findings in morning glory syndrome. Retina 2014;34:206-208.2371940110.1097/IAE.0b013e318296575c
– reference: Ide T, Ohguro N, Hayashi A, Yamamoto S, Nakagawa Y, Nagae Y, Tano Y: Optical coherence tomography patterns of choroidal osteoma. Am J Ophthalmol 2000;130:131-134.1100428010.1016/S0002-9394(00)00503-1
– reference: Erol MK, Coban DT, Ceran BB, Bulut M: Enhanced depth imaging optical coherence tomography and fundus autofluorescence findings in bilateral choroidal osteoma: a case report. Arq Bras Oftalmol 2013;76:189-191.2392908210.1590/S0004-27492013000300012
– reference: Shields CL, Perez B, Materin MA, Mehta S, Shields JA: Optical coherence tomography of choroidal osteoma in 22 cases: evidence for photoreceptor atrophy over the decalcified portion of the tumor. Ophthalmology 2007;114:e53-e58.1788417110.1016/j.ophtha.2007.07.037
– reference: Egawa M, Mitamura Y, Hayashi Y, Semba K, Naito T: Changes of fundus autofluorescence and spectral-domain optical coherence tomographic findings after treatment of primary intraocular lymphoma. J Ophthalmic Inflamm Infect 2014;4:7.2455925910.1186/1869-5760-4-7
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Snippet Purpose: To report the morphologic features of a choroidal osteoma using swept-source optical coherence tomography (SS-OCT) and fundus autofluorescence (FAF)....
To report the morphologic features of a choroidal osteoma using swept-source optical coherence tomography (SS-OCT) and fundus autofluorescence (FAF). Two eyes...
To report the morphologic features of a choroidal osteoma using swept-source optical coherence tomography (SS-OCT) and fundus autofluorescence (FAF).PURPOSETo...
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SubjectTerms Choroidal osteoma
Fundus autofluorescence
Ophthalmology
Published online: July, 2014
Published: July 2014
RE1-994
Swept-source optical coherence tomography
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Title Swept-Source Optical Coherence Tomographic Findings of Choroidal Osteoma
URI https://karger.com/doi/10.1159/000365184
https://cir.nii.ac.jp/crid/1873116917855425920
https://www.ncbi.nlm.nih.gov/pubmed/25120475
https://www.proquest.com/docview/1553703140
https://pubmed.ncbi.nlm.nih.gov/PMC4127548
https://doaj.org/article/c253b9e2fc8540d4b7c53dda851ecb2e
Volume 5
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