Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product

• Published in: Applied and Environmental Microbiology Vol. 70; no. 10; pp. 5810 - 5817
• Main Authors: Duncan, S.H, Louis, P, Flint, H.J
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.10.2004
• Subjects: Acids; Adult; Anaerostipes cacae; Anaerostipes caccae; Bacteria; Bacteria - classification; Bacteria - genetics; Bacteria - isolation & purification; Bacteria - metabolism; Bacteriology; Base Sequence; Bifidobacterium adolescentis; Biological and medical sciences; biosynthesis; Butyrates; Butyrates - metabolism; butyric acid; Carbon; Carbon - metabolism; chemistry; classification; colon; DNA, Bacterial; DNA, Bacterial - genetics; Electron Transport; Energy sources; Eubacterium; Eubacterium - classification; Eubacterium - genetics; Eubacterium - isolation & purification; Eubacterium - metabolism; Eubacterium hallii; Eubacterium rectale; Faecalibacterium prausnitzii; Feces; Feces - microbiology; Female; Fermentation; Fundamental and applied biological sciences. Psychology; genetics; Humans; intestinal microorganisms; isolation & purification; lactic acid; Lactic Acid - chemistry; Lactic Acid - metabolism; metabolism; Metabolism. Enzymes; Microbial Ecology; microbial physiology; Microbiology; Models, Biological; Phylogeny; RNA, Bacterial; RNA, Bacterial - genetics; RNA, Ribosomal, 16S; RNA, Ribosomal, 16S - genetics; Starch; Stereoisomerism; Human; Lactates; Bacteria; Colon; Feces; Fermentation; Butyrate

The microbial community of the human colon contains many bacteria that produce lactic acid, but lactate is normally detected only at low concentrations (<5 mM) in feces from healthy individuals. It is not clear, however, which bacteria are mainly responsible for lactate utilization in the human c...