Neuro-Nutraceutical Polyphenols: How Far Are We?

• Published in: Antioxidants Vol. 12; no. 3; p. 539
• Main Authors: Gentile, Maria Teresa, Camerino, Iolanda, Ciarmiello, Loredana, Woodrow, Pasqualina, Muscariello, Lidia, De Chiara, Ida, Pacifico, Severina
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 21.02.2023; MDPI
• Subjects: Acetylcholinesterase; Alzheimer's disease; Antioxidants; Bioavailability; Brain; Central nervous system; Cereals; Chelating agents; Copper; Dementia; Disease prevention; dyshomeostasis microbiota; Flavonoids; Food; Functional foods & nutraceuticals; gut–brain axis; Health aspects; health services; Hormones; humans; Intestinal microflora; intestinal microorganisms; iron; Metabolites; Microbiota; Molecular modelling; Nervous system; Neurodegeneration; Neurodegenerative diseases; neurodegenerative disorders; Neurological diseases; neurons; oxygen; Parkinson's disease; Phosphorylation; Phytochemicals; Polyphenols; Reactive oxygen species; Review; Tau protein; therapeutics; zinc; United States; polyphenols; gut–brain axis; dyshomeostasis microbiota; neurodegenerative disorders; central nervous system

The brain, composed of billions of neurons, is a complex network of interacting dynamical systems controlling all body functions. Neurons are the building blocks of the nervous system and their impairment of their functions could result in neurodegenerative disorders. Accumulating evidence shows an...