Mechanisms of anaphylaxis in human low-affinity IgG receptor locus knock-in mice - Gillis, Caitlin M.; Jönsson, Friederike; Mancardi, David A.; Tu, Naxin; Beutier, Héloïse; Van Rooijen, Nico; Macdonald, Lynn E.; Murphy, Andrew J.; Bruhns, Pierre (Journal of allergy and clinical immunology, 2017)
Keywords: Affinity; Allergies; Allergology; Allergy and Immunology; Anaphylaxis; Anaphylaxis - immunology; Animal models; Animals; Antigens; basophil; Disease Models, Animal; Gene Knock-In Techniques; GPI-Linked Proteins - immunology; Histamine; human FcγR; Human subjects; Humans; Hypothermia; IgG; Immunization; Immunoglobulin E; Immunoglobulin G; Immunoglobulins; Immunology; Immunotherapy; Intravenous administration; Kinases; knock-in mouse model; Leukocytes (basophilic); Leukocytes (neutrophilic); Life Sciences; macrophage; Mice; Mice, 129 Strain; Mice, Inbred C57BL; monocyte; Mortality; Myeloid cells; neutrophil; Neutrophils; Platelet-activating factor; Receptors, IgG - immunology; Rodents; Transgenic animals; SSC; histamine; BAC; IgG; macrophage; IVIG; platelet-activating factor; basophil; neutrophil; BAL; ES; ASA; Anaphylaxis; PAF; knock-in mouse model; monocyte; HA; human FcγR; NK; PAF-R; PSA; Heat aggregated; Platelet-activating factor receptor; Bronchoalveolar lavage; Active systemic anaphylaxis; Intravenous immunoglobulin; Embryonic stem; Side scatter; Natural killer; Passive systemic anaphylaxis; Bacterial artificial chromosome