Exercise‐induced metabolic fluctuations influence AMPK, p38‐MAPK and CaMKII phosphorylation in human skeletal muscle

• Published in: Physiological reports Vol. 3; no. 9; pp. e12462 - n/a
• Main Authors: Combes, Adrien, Dekerle, Jeanne, Webborn, Nick, Watt, Peter, Bougault, Valérie, Daussin, Frédéric N.
• Format: Journal Article
• Language: English
• Published: United States Wiley 01.09.2015; John Wiley & Sons, Ltd
• Series: Physiological reports
• Subjects: AMPK; CaMKII; exercise modality; Life Sciences; mitochondrial biogenesis; Original Research; p38‐MAPK; AMPK; CaMKII; p38‐MAPK; mitochondrial biogenesis; exercise modality; p38-MAPK

During transition from rest to exercise, metabolic reaction rates increase substantially to sustain intracellular ATP use. These metabolic demands activate several kinases that initiate signal transduction pathways which modulate transcriptional regulation of mitochondrial biogenesis. The purpose of...