Homeostatic metaplasticity of corticospinal excitatory and intracortical inhibitory neural circuits in human motor cortex

• Published in: The Journal of physiology Vol. 590; no. 22; pp. 5765 - 5781
• Main Authors: Murakami, Takenobu, Müller‐Dahlhaus, Florian, Lu, Ming‐Kuei, Ziemann, Ulf
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 15.11.2012; Wiley Subscription Services, Inc; Blackwell Science Inc
• Subjects: Achievement tests; Adult; Evoked Potentials, Motor; Female; GABAergic Neurons - physiology; Homeostasis - physiology; Humans; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Motor Cortex - physiology; Nerve Net - physiology; Neural Inhibition; Neuroscience: Behavioural/Systems/Cognitive; Physiology; Pyramidal Tracts - physiology; Theta Rhythm; Transcranial Magnetic Stimulation
• ISSN: 0022-3751; 1469-7793; 1469-7793
• DOI: 10.1113/jphysiol.2012.238519

Key points •  Homeostatic metaplasticity is an important mechanism for maintaining overall synaptic weight of a neuronal network in the physiological range. •  Homeostatic metaplasticity has been demonstrated, so far largely exclusively, for excitatory synaptic neurotransmission. •  New non‐invasive...