The effect of acute sleep deprivation on skeletal muscle protein synthesis and the hormonal environment

• Published in: Physiological reports Vol. 9; no. 1; pp. e14660 - n/a
• Main Authors: Lamon, Séverine, Morabito, Aimee, Arentson‐Lantz, Emily, Knowles, Olivia, Vincent, Grace Elizabeth, Condo, Dominique, Alexander, Sarah Elizabeth, Garnham, Andrew, Paddon‐Jones, Douglas, Aisbett, Brad
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.01.2021; John Wiley and Sons Inc
• Subjects: Adult; Body composition; Chronic illnesses; Cortisol; Female; Females; hormones; Humans; Hydrocortisone - blood; Male; Males; Menstruation; Metabolism; muscle; muscle protein synthesis; Muscle Proteins - metabolism; Muscle, Skeletal - metabolism; Muscle, Skeletal - pathology; Musculoskeletal system; Original Research; Physiology; Protein biosynthesis; Protein synthesis; Proteins; Proteolysis; Skeletal muscle; Sleep deprivation; Sleep Deprivation - blood; Sleep Deprivation - metabolism; Testosterone; Testosterone - blood; Young Adult; Young adults; muscle protein synthesis; sleep deprivation; hormones; muscle

Chronic sleep loss is a potent catabolic stressor, increasing the risk of metabolic dysfunction and loss of muscle mass and function. To provide mechanistic insight into these clinical outcomes, we sought to determine if acute sleep deprivation blunts skeletal muscle protein synthesis and promotes a...