Comparative Efficacy of Chimeric Porcine Circovirus (PCV) Vaccines against Experimental Heterologous PCV2d Challenges

• Published in: Veterinary sciences Vol. 10; no. 2; p. 80
• Main Authors: Wongchanapai, Pichanun, Yamsakul, Panuwat, Arunorat, Jirapat, Guntawang, Thunyamas, Sittisak, Tidaratt, Srivorakul, Saralee, Photichai, Kornravee, Thanawongnuwech, Roongroje, Sukmak, Manakorn, Pringproa, Kidsadagon
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 21.01.2023; MDPI
• Subjects: Analysis; Antibodies; Antigens; blood; challenge; chimeric vaccine; Genotypes; herds; heterologous PCV2; Histopathology; Hogs; Immune response; Immunization; Immunoglobulin G; Immunology; Infectious diseases; Inoculation; Laboratory animals; Lungs; Lymphatic system; males; Pathogens; Porcine circovirus; Porcine circovirus type 2; Specific pathogen free; specific pathogen-free animals; Swine; Vaccination; Vaccines; Variance analysis; Viremia; Thailand; United States > US; challenge; Porcine circovirus type 2; heterologous PCV2; chimeric vaccine

The objective of this study was to evaluate the efficacy of two multivalent commercial porcine circovirus (PCV) vaccines against heterologous PCV2d challenges. A total of 24 crossbred male pigs aged 26 days selected from a specific pathogen-free herd were randomly divided into four groups (six pigs...