Adaptations in brain reward circuitry underlie palatable food cravings and anxiety induced by high-fat diet withdrawal

Objective: To identify the emotional and motivational processes that reinstate palatable food intake following removal of high-fat diet (HFD) and associated neuroadaptations tied to neurochemical and behavioural changes underlying dopaminergic function. Methods: Adult male C57Bl6 mice were placed on...

Full description

Saved in:
Bibliographic Details
Published inInternational Journal of Obesity Vol. 37; no. 9; pp. 1183 - 1191
Main Authors Sharma, S, Fernandes, M F, Fulton, S
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.09.2013
Nature Publishing Group
Subjects
631/378/1488/393
631/378/1689/1300
631/378/1689/1831
Animals
Anxiety
Anxiety - metabolism
Anxiety - physiopathology
Behavior, Animal
Biological and medical sciences
Blotting, Western
Brain - metabolism
Brain - physiopathology
Brain stimulation rewards
Brain-Derived Neurotrophic Factor - metabolism
Diet
Diet, High-Fat
Disease Models, Animal
Dopamine - metabolism
Epidemiology
Food
Health Promotion and Disease Prevention
Hypersensitivity
Influence
Internal Medicine
Ketogenic diet
Male
Medical sciences
Medicine
Medicine & Public Health
Metabolic Diseases
Mice
Mice, Inbred C57BL
Motor Activity
Neuronal Plasticity
Obesity
Obesity - etiology
Obesity - metabolism
Obesity - physiopathology
original-article
Physiological aspects
Plasticity
Promoter Regions, Genetic
Psychological aspects
Public Health
Receptors, Corticotropin-Releasing Hormone - metabolism
Reward
Stress, Psychological - metabolism
Stress, Psychological - physiopathology
Sucrose - metabolism
Tyrosine 3-Monooxygenase - metabolism
reward
anxiety
stress
high-fat food
mesolimbic
dopamine
Affect affectivity
Brain
Obesity
Dopamine
Nutrition
Craving
Central nervous system
Nutrition disorder
Anxiety disorder
Metabolic diseases
Catecholamine
Stress
Feeding
Encephalon
Diet
Neurotransmitter
Fat
Anxiety
Reward
Nutritional status
Adaptation
Food
Online AccessGet full text

Cover

Abstract Objective: To identify the emotional and motivational processes that reinstate palatable food intake following removal of high-fat diet (HFD) and associated neuroadaptations tied to neurochemical and behavioural changes underlying dopaminergic function. Methods: Adult male C57Bl6 mice were placed on a HFD (58% kcal fat) or ingredient-matched, low-fat diet (LFD; 11% kcal fat) for 6 weeks. At the end of diet-regimen mice were either maintained on their respective diets, or HFD and LFD were replaced with normal chow (withdrawal). Effort-based operant responding for sucrose and high-fat food rewards was measured along with basal and stress-induced corticosterone levels and anxiety (elevated-plus maze). Protein levels for tyrosine hydroxylase (TH), corticosterone releasing factor type 1 receptor (CRF-R1), brain-derived neurotrophic factor (BDNF), phospho-CREB (pCREB) and ΔFosB (truncated splice variant of FosB) were assessed in the amygdala, nucleus accumbens (NAc) and ventral tegmental area (VTA) via western immunoblotting. Results: Six weeks of HFD resulting in significant weight gain elicited sucrose anhedonia, anxiety-like behaviour and hypothalamic-pituitary-adrenocortical axis (HPA) hypersensitivity to stress. Withdrawal from HFD but not LFD-potentiated anxiety and basal corticosterone levels and enhanced motivation for sucrose and high-fat food rewards. Chronic high-fat feeding reduced CRF-R1 and increased BDNF and pCREB protein levels in the amygdala and reduced TH and increased ΔFosB protein in NAc and VTA. Heightened palatable food reward in mice withdrawn from HFD coincided with increased BDNF protein levels in NAc and decreased TH and pCREB expression in the amygdala. Conclusion: Anhedonia, anxiety and sensitivity to stressors develops during the course of HFD and may have a key role in a vicious cycle that perpetuates high-fat feeding and the development of obesity. Removal of HFD enhances stress responses and heightens vulnerability for palatable foods by increasing food-motivated behaviour. Lasting changes in dopamine and plasticity-related signals in reward circuitry may promote negative emotional states, overeating and palatable food relapse.
AbstractList To identify the emotional and motivational processes that reinstate palatable food intake following removal of high-fat diet (HFD) and associated neuroadaptations tied to neurochemical and behavioural changes underlying dopaminergic function. Adult male C57Bl6 mice were placed on a HFD (58% kcal fat) or ingredient-matched, low-fat diet (LFD; 11% kcal fat) for 6 weeks. At the end of diet-regimen mice were either maintained on their respective diets, or HFD and LFD were replaced with normal chow (withdrawal). Effort-based operant responding for sucrose and high-fat food rewards was measured along with basal and stress-induced corticosterone levels and anxiety (elevated-plus maze). Protein levels for tyrosine hydroxylase (TH), corticosterone releasing factor type 1 receptor (CRF-R1), brain-derived neurotrophic factor (BDNF), phospho-CREB (pCREB) and ΔFosB (truncated splice variant of FosB) were assessed in the amygdala, nucleus accumbens (NAc) and ventral tegmental area (VTA) via western immunoblotting. Six weeks of HFD resulting in significant weight gain elicited sucrose anhedonia, anxiety-like behaviour and hypothalamic-pituitary-adrenocortical axis (HPA) hypersensitivity to stress. Withdrawal from HFD but not LFD-potentiated anxiety and basal corticosterone levels and enhanced motivation for sucrose and high-fat food rewards. Chronic high-fat feeding reduced CRF-R1 and increased BDNF and pCREB protein levels in the amygdala and reduced TH and increased ΔFosB protein in NAc and VTA. Heightened palatable food reward in mice withdrawn from HFD coincided with increased BDNF protein levels in NAc and decreased TH and pCREB expression in the amygdala. Anhedonia, anxiety and sensitivity to stressors develops during the course of HFD and may have a key role in a vicious cycle that perpetuates high-fat feeding and the development of obesity. Removal of HFD enhances stress responses and heightens vulnerability for palatable foods by increasing food-motivated behaviour. Lasting changes in dopamine and plasticity-related signals in reward circuitry may promote negative emotional states, overeating and palatable food relapse.
OBJECTIVE: To identify the emotional and motivational processes that reinstate palatable food intake following removal of high-fat diet (HFD) and associated neuroadaptations tied to neurochemical and behavioural changes underlying dopaminergic function METHODS: Adult male C57Bl6 mice were placed on a HFD (58% kcal fat) or ingredient-matched, low-fat diet (LFD;11% kcal fat) for 6 weeks. At the end of diet-regimen mice were either maintained on their respective diets, or HFD and LFD were replaced with normal chow (withdrawal). Effort-based operant responding for sucrose and high-fat food rewards was measured along with basal and stress-induced corticosterone levels and anxiety (elevated-plus maze). Protein levels for tyrosine hydroxylase (TH), corticosterone releasing factor type 1 receptor (CRF-R1), brain-derived neurotrophic factor (BDNF), phospho-CREB (pCREB) and ΔFosB (truncated splice variant of FosB) were assessed in the amygdala, nucleus accumbens (NAc) and ventral tegmental area (VTA) via western immunoblotting. RESULTS: Six weeks of HFD resulting in significant weight gain elicited sucrose anhedonia, anxiety-like behaviour and hypothalamic-pituitary-adrenocortical axis (HPA) hypersensitivity to stress. Withdrawal from HFD but not LFD-potentiated anxiety and basal corticosterone levels and enhanced motivation for sucrose and high-fat food rewards. Chronic high-fat feeding reduced CRF-R1 and increased BDNF and pCREB protein levels in the amygdala and reduced TH and increased ΔFosB protein in NAc and VTA. Heightened palatable food reward in mice withdrawn from HFD coincided with increased BDNF protein levels in NAc and decreased TH and pCREB expression in the amygdala. CONCLUSION: Anhedonia, anxiety and sensitivity to stressors develops during the course of HFD and may have a key role in a vicious cycle that perpetuates high-fat feeding and the development of obesity. Removal of HFD enhances stress responses an heightens vulnerability for palatable foods by increasing food-motivated behaviour. Lasting changes in dopamine and plasticity-related signals in reward circuitry may promote negative emotional states, overeating and palatable food relapse. International Journal of Obesity (2013) 37, 1183-1191; doi: 10.1038/ijo.2012.197; published online 11 December 2012 Keywords: high-fat food; reward; anxiety; stress; mesolimbic; dopamine
Objective: To identify the emotional and motivational processes that reinstate palatable food intake following removal of high-fat diet (HFD) and associated neuroadaptations tied to neurochemical and behavioural changes underlying dopaminergic function. Methods: Adult male C57Bl6 mice were placed on a HFD (58% kcal fat) or ingredient-matched, low-fat diet (LFD; 11% kcal fat) for 6 weeks. At the end of diet-regimen mice were either maintained on their respective diets, or HFD and LFD were replaced with normal chow (withdrawal). Effort-based operant responding for sucrose and high-fat food rewards was measured along with basal and stress-induced corticosterone levels and anxiety (elevated-plus maze). Protein levels for tyrosine hydroxylase (TH), corticosterone releasing factor type 1 receptor (CRF-R1), brain-derived neurotrophic factor (BDNF), phospho-CREB (pCREB) and Delta FosB (truncated splice variant of FosB) were assessed in the amygdala, nucleus accumbens (NAc) and ventral tegmental area (VTA) via western immunoblotting. Results: Six weeks of HFD resulting in significant weight gain elicited sucrose anhedonia, anxiety-like behaviour and hypothalamic-pituitary-adrenocortical axis (HPA) hypersensitivity to stress. Withdrawal from HFD but not LFD-potentiated anxiety and basal corticosterone levels and enhanced motivation for sucrose and high-fat food rewards. Chronic high-fat feeding reduced CRF-R1 and increased BDNF and pCREB protein levels in the amygdala and reduced TH and increased Delta FosB protein in NAc and VTA. Heightened palatable food reward in mice withdrawn from HFD coincided with increased BDNF protein levels in NAc and decreased TH and pCREB expression in the amygdala. Conclusion: Anhedonia, anxiety and sensitivity to stressors develops during the course of HFD and may have a key role in a vicious cycle that perpetuates high-fat feeding and the development of obesity. Removal of HFD enhances stress responses and heightens vulnerability for palatable foods by increasing food-motivated behaviour. Lasting changes in dopamine and plasticity-related signals in reward circuitry may promote negative emotional states, overeating and palatable food relapse.
To identify the emotional and motivational processes that reinstate palatable food intake following removal of high-fat diet (HFD) and associated neuroadaptations tied to neurochemical and behavioural changes underlying dopaminergic function. Adult male C57Bl6 mice were placed on a HFD (58% kcal fat) or ingredient-matched, low-fat diet (LFD; 11% kcal fat) for 6 weeks. At the end of diet-regimen mice were either maintained on their respective diets, or HFD and LFD were replaced with normal chow (withdrawal). Effort-based operant responding for sucrose and high-fat food rewards was measured along with basal and stress-induced corticosterone levels and anxiety (elevated-plus maze). Protein levels for tyrosine hydroxylase (TH), corticosterone releasing factor type 1 receptor (CRF-R1), brain-derived neurotrophic factor (BDNF), phospho-CREB (pCREB) and ΔFosB (truncated splice variant of FosB) were assessed in the amygdala, nucleus accumbens (NAc) and ventral tegmental area (VTA) via western immunoblotting. Six weeks of HFD resulting in significant weight gain elicited sucrose anhedonia, anxiety-like behaviour and hypothalamic-pituitary-adrenocortical axis (HPA) hypersensitivity to stress. Withdrawal from HFD but not LFD-potentiated anxiety and basal corticosterone levels and enhanced motivation for sucrose and high-fat food rewards. Chronic high-fat feeding reduced CRF-R1 and increased BDNF and pCREB protein levels in the amygdala and reduced TH and increased ΔFosB protein in NAc and VTA. Heightened palatable food reward in mice withdrawn from HFD coincided with increased BDNF protein levels in NAc and decreased TH and pCREB expression in the amygdala. Anhedonia, anxiety and sensitivity to stressors develops during the course of HFD and may have a key role in a vicious cycle that perpetuates high-fat feeding and the development of obesity. Removal of HFD enhances stress responses and heightens vulnerability for palatable foods by increasing food-motivated behaviour. Lasting changes in dopamine and plasticity-related signals in reward circuitry may promote negative emotional states, overeating and palatable food relapse.
OBJECTIVETo identify the emotional and motivational processes that reinstate palatable food intake following removal of high-fat diet (HFD) and associated neuroadaptations tied to neurochemical and behavioural changes underlying dopaminergic function.METHODSAdult male C57Bl6 mice were placed on a HFD (58% kcal fat) or ingredient-matched, low-fat diet (LFD; 11% kcal fat) for 6 weeks. At the end of diet-regimen mice were either maintained on their respective diets, or HFD and LFD were replaced with normal chow (withdrawal). Effort-based operant responding for sucrose and high-fat food rewards was measured along with basal and stress-induced corticosterone levels and anxiety (elevated-plus maze). Protein levels for tyrosine hydroxylase (TH), corticosterone releasing factor type 1 receptor (CRF-R1), brain-derived neurotrophic factor (BDNF), phospho-CREB (pCREB) and ΔFosB (truncated splice variant of FosB) were assessed in the amygdala, nucleus accumbens (NAc) and ventral tegmental area (VTA) via western immunoblotting.RESULTSSix weeks of HFD resulting in significant weight gain elicited sucrose anhedonia, anxiety-like behaviour and hypothalamic-pituitary-adrenocortical axis (HPA) hypersensitivity to stress. Withdrawal from HFD but not LFD-potentiated anxiety and basal corticosterone levels and enhanced motivation for sucrose and high-fat food rewards. Chronic high-fat feeding reduced CRF-R1 and increased BDNF and pCREB protein levels in the amygdala and reduced TH and increased ΔFosB protein in NAc and VTA. Heightened palatable food reward in mice withdrawn from HFD coincided with increased BDNF protein levels in NAc and decreased TH and pCREB expression in the amygdala.CONCLUSIONAnhedonia, anxiety and sensitivity to stressors develops during the course of HFD and may have a key role in a vicious cycle that perpetuates high-fat feeding and the development of obesity. Removal of HFD enhances stress responses and heightens vulnerability for palatable foods by increasing food-motivated behaviour. Lasting changes in dopamine and plasticity-related signals in reward circuitry may promote negative emotional states, overeating and palatable food relapse.
International Journal of Obesity (2013) 37, 1183-1191; doi: 10.1038/ijo.2012.197; published online 11 December 2012
Objective: To identify the emotional and motivational processes that reinstate palatable food intake following removal of high-fat diet (HFD) and associated neuroadaptations tied to neurochemical and behavioural changes underlying dopaminergic function. Methods: Adult male C57Bl6 mice were placed on a HFD (58% kcal fat) or ingredient-matched, low-fat diet (LFD; 11% kcal fat) for 6 weeks. At the end of diet-regimen mice were either maintained on their respective diets, or HFD and LFD were replaced with normal chow (withdrawal). Effort-based operant responding for sucrose and high-fat food rewards was measured along with basal and stress-induced corticosterone levels and anxiety (elevated-plus maze). Protein levels for tyrosine hydroxylase (TH), corticosterone releasing factor type 1 receptor (CRF-R1), brain-derived neurotrophic factor (BDNF), phospho-CREB (pCREB) and ΔFosB (truncated splice variant of FosB) were assessed in the amygdala, nucleus accumbens (NAc) and ventral tegmental area (VTA) via western immunoblotting. Results: Six weeks of HFD resulting in significant weight gain elicited sucrose anhedonia, anxiety-like behaviour and hypothalamic-pituitary-adrenocortical axis (HPA) hypersensitivity to stress. Withdrawal from HFD but not LFD-potentiated anxiety and basal corticosterone levels and enhanced motivation for sucrose and high-fat food rewards. Chronic high-fat feeding reduced CRF-R1 and increased BDNF and pCREB protein levels in the amygdala and reduced TH and increased ΔFosB protein in NAc and VTA. Heightened palatable food reward in mice withdrawn from HFD coincided with increased BDNF protein levels in NAc and decreased TH and pCREB expression in the amygdala. Conclusion: Anhedonia, anxiety and sensitivity to stressors develops during the course of HFD and may have a key role in a vicious cycle that perpetuates high-fat feeding and the development of obesity. Removal of HFD enhances stress responses and heightens vulnerability for palatable foods by increasing food-motivated behaviour. Lasting changes in dopamine and plasticity-related signals in reward circuitry may promote negative emotional states, overeating and palatable food relapse.
Audience Academic
Author Fulton, S
Sharma, S
Fernandes, M F
Author_xml – sequence: 1
  givenname: S
  surname: Sharma
  fullname: Sharma, S
  organization: CRCHUM and Montreal Diabetes Research Centre, Department of Nutrition, Faculty of Medicine, Université de Montreal
– sequence: 2
  givenname: M F
  surname: Fernandes
  fullname: Fernandes, M F
  organization: CRCHUM and Montreal Diabetes Research Centre, Department of Nutrition, Faculty of Medicine, Université de Montreal
– sequence: 3
  givenname: S
  surname: Fulton
  fullname: Fulton, S
  email: stephanie.fulton@umontreal.ca
  organization: CRCHUM and Montreal Diabetes Research Centre, Department of Nutrition, Faculty of Medicine, Université de Montreal
BackLink http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27701833$$DView record in Pascal Francis
https://www.ncbi.nlm.nih.gov/pubmed/23229740$$D View this record in MEDLINE/PubMed
BookMark eNqN0s2PEyEYB2Bi1rjd6s2zmcRoPDgVBijMsdn4lWziRc-Td_hoaShTgdna_176obtr9mAIQwIPL2H4XaGLMASD0EuCZwRT-cGth1mDSTMjrXiCJoSJec1ZKy7QBFMsaszn_BJdpbTGGHOOm2fosqFN0wqGJ-h2oWGbIbshpMqFqo9QvtHsIOpKuahGl-O-GoM20TtTbcFDht6byg5DERFuXVimCoIu_ZczeV_K6FEZXfX7auWWq9pCrnRZqXYur3SEHfjn6KkFn8yL8zhFPz59_H79pb759vnr9eKmVlyyXBsimWWMKcsltXIOjCple7BaQ18mGyWgkYIYQzThbaOAiVZBzwXr-xYTOkXvTnW3cfg5mpS7jUvKeA_BDGPqCKNtQykR8_-hZE44PtLX_9D1MMZQLnJUWArM5J1agjedC3bIEdShaLegjEtJWWlTNHtElabNxqny1NaV-Qcb3t7bsDLg8yoNfjw-4UP4_gRVHFKKxnbb6DYQ9x3B3SE6XYlOd4hOV6JT-KvzpcZ-Y_Rf_CcrBbw5A0gKvI0QlEt3TghMJKXF1SeXylJYmnjv7zx28G_Nu9tY
CODEN IJOBDP
CitedBy_id crossref_primary_10_1016_j_biopsych_2022_10_003
crossref_primary_10_1371_journal_pone_0176554
crossref_primary_10_3389_fphar_2018_01061
crossref_primary_10_3390_nu13051607
crossref_primary_10_3109_10253890_2014_967677
crossref_primary_10_1016_j_physbeh_2015_10_009
crossref_primary_10_1021_acschemneuro_1c00723
crossref_primary_10_1016_j_ijdevneu_2014_11_003
crossref_primary_10_1016_j_physbeh_2016_10_006
crossref_primary_10_3390_nu11092253
crossref_primary_10_1080_1028415X_2020_1751508
crossref_primary_10_1016_j_appet_2019_104553
crossref_primary_10_1111_gbb_12185
crossref_primary_10_1016_j_jaac_2018_06_039
crossref_primary_10_3389_fnins_2019_00391
crossref_primary_10_1002_bdr2_1173
crossref_primary_10_1371_journal_pone_0087729
crossref_primary_10_1007_s00787_017_0959_1
crossref_primary_10_1093_ijnp_pyw014
crossref_primary_10_1007_s40473_018_0169_2
crossref_primary_10_1002_eat_23917
crossref_primary_10_1073_pnas_1515724113
crossref_primary_10_1016_j_cmet_2023_02_015
crossref_primary_10_1038_mp_2017_38
crossref_primary_10_1007_s00213_019_05259_3
crossref_primary_10_1016_j_tics_2019_01_005
crossref_primary_10_1038_ijo_2016_235
crossref_primary_10_1038_npp_2016_269
crossref_primary_10_3389_fnins_2020_00562
crossref_primary_10_1016_S2352_4642_19_30404_3
crossref_primary_10_1080_1028415X_2018_1465713
crossref_primary_10_1038_npp_2014_98
crossref_primary_10_1016_j_bbr_2022_114077
crossref_primary_10_3389_fnbeh_2018_00144
crossref_primary_10_1111_ajad_13152
crossref_primary_10_1016_j_brainresbull_2019_07_002
crossref_primary_10_1016_j_alcohol_2020_03_007
crossref_primary_10_1186_s12937_016_0204_7
crossref_primary_10_3389_fnhum_2016_00514
crossref_primary_10_1016_j_bbr_2018_12_031
crossref_primary_10_1016_j_neuropharm_2019_03_035
crossref_primary_10_31887_DCNS_2014_16_3_jbolton
crossref_primary_10_1371_journal_pone_0194431
crossref_primary_10_3389_fnagi_2017_00164
crossref_primary_10_3389_fpsyg_2019_01966
crossref_primary_10_3390_nu14204302
crossref_primary_10_1111_adb_12595
crossref_primary_10_1016_j_cobeha_2016_03_010
crossref_primary_10_1111_jne_12718
crossref_primary_10_1002_oby_22758
crossref_primary_10_1016_j_jnutbio_2022_109158
crossref_primary_10_3389_fnins_2017_00469
crossref_primary_10_1016_j_physbeh_2023_114317
crossref_primary_10_1016_j_neuropharm_2016_09_020
crossref_primary_10_1007_s11011_016_9940_9
crossref_primary_10_1016_j_neuropharm_2017_11_041
crossref_primary_10_1016_j_bbi_2019_09_001
crossref_primary_10_1007_s40519_016_0275_7
crossref_primary_10_1016_j_psyneuen_2017_06_002
crossref_primary_10_1016_j_foodchem_2024_138560
crossref_primary_10_1016_j_toxlet_2019_03_009
crossref_primary_10_1016_j_brainres_2024_148996
crossref_primary_10_1080_1028415X_2020_1809879
crossref_primary_10_1007_s10905_016_9591_z
crossref_primary_10_1016_j_biopsych_2015_11_019
crossref_primary_10_1080_1028415X_2019_1651104
crossref_primary_10_1038_npp_2015_49
crossref_primary_10_1038_npp_2015_207
crossref_primary_10_1016_j_tem_2021_10_005
crossref_primary_10_1007_s00213_017_4630_9
crossref_primary_10_3390_nu10040477
crossref_primary_10_3390_nu13072341
crossref_primary_10_3389_fnbeh_2023_1240748
crossref_primary_10_1016_j_cnd_2022_07_001
crossref_primary_10_1038_s41598_020_78897_9
crossref_primary_10_1016_j_psyneuen_2021_105147
crossref_primary_10_1016_j_appet_2013_12_004
crossref_primary_10_1016_j_bcp_2022_115015
crossref_primary_10_1038_s41598_019_54540_0
crossref_primary_10_1016_j_bbr_2016_04_052
crossref_primary_10_1152_ajpendo_00174_2020
crossref_primary_10_1007_s00394_015_0980_4
crossref_primary_10_1016_j_psyneuen_2019_104430
crossref_primary_10_1016_j_neuroscience_2014_05_028
crossref_primary_10_1186_s40168_023_01526_w
crossref_primary_10_1016_j_bbr_2016_06_052
crossref_primary_10_1111_nyas_13665
crossref_primary_10_3389_fendo_2019_00704
crossref_primary_10_1016_j_neuroscience_2016_01_070
crossref_primary_10_1002_brb3_1340
crossref_primary_10_1002_oby_23253
crossref_primary_10_1016_j_ntt_2022_107094
crossref_primary_10_1080_1028415X_2017_1358481
crossref_primary_10_2174_1381612826666200204141057
crossref_primary_10_1016_j_molmet_2018_01_018
crossref_primary_10_1016_j_arr_2014_10_002
crossref_primary_10_1017_S0954422421000196
crossref_primary_10_3389_fpsyg_2020_564413
crossref_primary_10_1016_j_ijdevneu_2017_09_003
crossref_primary_10_1016_j_physbeh_2016_05_013
crossref_primary_10_1007_s11011_021_00812_6
crossref_primary_10_1016_j_physbeh_2019_112722
crossref_primary_10_1007_s00424_021_02583_6
crossref_primary_10_1007_s11011_015_9682_0
crossref_primary_10_1016_j_neuroscience_2021_02_006
crossref_primary_10_1016_j_pnpbp_2014_11_008
crossref_primary_10_1113_JP275177
crossref_primary_10_1038_s41386_024_01855_w
crossref_primary_10_3389_fnut_2019_00190
crossref_primary_10_1134_S1819712416010153
crossref_primary_10_1089_met_2019_0108
crossref_primary_10_1016_j_bbr_2014_09_019
crossref_primary_10_1016_j_neuropharm_2021_108556
crossref_primary_10_3389_fnbeh_2016_00189
crossref_primary_10_1089_jmf_2015_3600
crossref_primary_10_1007_s11695_020_04565_6
crossref_primary_10_1523_JNEUROSCI_3122_14_2015
crossref_primary_10_1016_j_appet_2024_107355
crossref_primary_10_1113_JP280412
crossref_primary_10_1038_s41386_021_00957_z
crossref_primary_10_3390_ijms231710089
crossref_primary_10_3389_fnmol_2022_1020903
crossref_primary_10_1016_j_neuroscience_2023_08_019
crossref_primary_10_1016_j_bbr_2017_05_014
crossref_primary_10_3390_nu10030365
crossref_primary_10_1093_toxsci_kfy171
crossref_primary_10_1016_j_neuroscience_2015_03_068
crossref_primary_10_1016_j_ynstr_2018_05_005
crossref_primary_10_3390_ijerph17082647
crossref_primary_10_1016_j_pbb_2016_12_009
crossref_primary_10_1016_j_tips_2013_11_003
crossref_primary_10_3389_fendo_2021_667066
crossref_primary_10_1016_j_appet_2021_105112
crossref_primary_10_1016_j_appet_2021_105233
crossref_primary_10_1016_j_bbr_2019_112399
crossref_primary_10_1080_01677063_2018_1526934
crossref_primary_10_1038_mp_2016_50
crossref_primary_10_1038_s41386_022_01289_2
crossref_primary_10_1111_mcn_12992
crossref_primary_10_1177_0269881117742116
Cites_doi 10.1016/j.biopsych.2004.02.032
10.1016/j.mehy.2008.11.035
10.1038/nn.2551
10.1016/j.brainres.2009.02.075
10.1111/j.1460-9568.2007.05473.x
10.1038/npp.2009.179
10.1038/nn1812
10.1016/S0893-133X(00)00148-2
10.1016/0165-0270(95)00153-0
10.1016/j.neuropharm.2008.06.075
10.1523/JNEUROSCI.6604-10.2011
10.1523/JNEUROSCI.2105-10.2010
10.1111/j.1460-9568.2010.07148.x
10.1016/j.neuron.2006.09.006
10.1038/npp.2010.181
10.1046/j.1471-4159.2003.02214.x
10.1007/BF02244188
10.1007/s00213-009-1523-6
10.1126/science.1188472
10.1007/s00213-009-1474-y
10.1111/j.1749-6632.1999.tb07876.x
10.1530/JOE-12-0056
10.1002/(SICI)1098-2396(19990615)32:4<254::AID-SYN2>3.0.CO;2-H
10.1038/nature09820
10.1073/pnas.0707585104
10.1016/j.neubiorev.2005.04.017
10.1007/BF02246966
10.1016/j.appet.2006.05.016
10.1038/sj.npp.1300964
10.1038/nn1929
10.1016/S0006-8993(98)01191-3
10.1523/JNEUROSCI.22-01-00193.2002
10.1016/j.pneurobio.2009.05.003
10.1016/S0896-6273(00)80491-2
10.1146/annurev.neuro.29.051605.113009
10.1111/j.1749-6632.1998.tb09011.x
10.1016/j.brainres.2009.03.038
10.1007/s11064-010-0313-1
10.1152/ajpregu.90309.2008
10.1097/ADM.0b013e318199cd20
10.1007/BF02247719
10.1016/j.psyneuen.2008.08.010
10.1038/nrn3111
10.1523/JNEUROSCI.5768-09.2010
10.1016/j.neuroscience.2009.02.007
10.1016/j.physbeh.2011.11.019
10.1016/j.biopsych.2009.11.007
10.1523/JNEUROSCI.5405-06.2007
10.1038/oby.2002.66
10.1037/a0013111
10.1016/j.yfrne.2009.10.003
10.1046/j.1471-4159.2001.00309.x
10.1038/npp.2008.78
10.1016/j.neuropharm.2008.06.059
10.1001/archgenpsychiatry.2009.104
10.1126/science.282.5397.2272
10.1038/sj.npp.1301430
10.1016/j.biopsych.2006.09.032
10.1016/j.physbeh.2008.01.008
10.1073/pnas.0908789106
10.1016/j.tics.2010.11.001
10.1111/j.1471-4159.2012.07649.x
ContentType Journal Article
Copyright Macmillan Publishers Limited 2013
2014 INIST-CNRS
COPYRIGHT 2013 Nature Publishing Group
Copyright Nature Publishing Group Sep 2013
Copyright_xml – notice: Macmillan Publishers Limited 2013
– notice: 2014 INIST-CNRS
– notice: COPYRIGHT 2013 Nature Publishing Group
– notice: Copyright Nature Publishing Group Sep 2013
DBID IQODW
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
3V.
7T2
7TK
7TS
7X2
7X7
7XB
88E
88G
8AO
8C1
8FE
8FH
8FI
8FJ
8FK
ABUWG
AFKRA
ATCPS
AZQEC
BBNVY
BENPR
BHPHI
C1K
CCPQU
DWQXO
FYUFA
GHDGH
GNUQQ
HCIFZ
K9.
LK8
M0K
M0S
M1P
M2M
M7P
PQEST
PQQKQ
PQUKI
PSYQQ
Q9U
7X8
DOI 10.1038/ijo.2012.197
DatabaseName Pascal-Francis
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
ProQuest Central (Corporate)
Health and Safety Science Abstracts (Full archive)
Neurosciences Abstracts
Physical Education Index
Agricultural Science Collection
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Psychology Database (Alumni)
ProQuest Pharma Collection
Public Health Database
ProQuest SciTech Collection
ProQuest Natural Science Collection
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
Agricultural & Environmental Science Collection
ProQuest Central Essentials
Biological Science Collection
ProQuest Central
Natural Science Collection
Environmental Sciences and Pollution Management
ProQuest One Community College
ProQuest Central
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
SciTech Premium Collection
ProQuest Health & Medical Complete (Alumni)
Biological Sciences
Agriculture Science Database
Health & Medical Collection (Alumni Edition)
PML(ProQuest Medical Library)
Psychology Database
Biological Science Database
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest One Psychology
ProQuest Central Basic
MEDLINE - Academic
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
Agricultural Science Database
ProQuest One Psychology
ProQuest Central Student
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
ProQuest Natural Science Collection
ProQuest Pharma Collection
Physical Education Index
Environmental Sciences and Pollution Management
ProQuest Central
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
Natural Science Collection
ProQuest Central Korea
Agricultural & Environmental Science Collection
Biological Science Collection
Health & Safety Science Abstracts
ProQuest Medical Library (Alumni)
ProQuest Public Health
ProQuest Biological Science Collection
ProQuest Central Basic
ProQuest One Academic Eastern Edition
Agricultural Science Collection
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest Psychology Journals (Alumni)
Biological Science Database
ProQuest SciTech Collection
Neurosciences Abstracts
ProQuest Hospital Collection (Alumni)
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest Psychology Journals
ProQuest One Academic UKI Edition
ProQuest One Academic
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList Agricultural Science Database

Neurosciences Abstracts
MEDLINE
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 3
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Public Health
Diet & Clinical Nutrition
Recreation & Sports
EISSN 1476-5497
EndPage 1191
ExternalDocumentID 3067209171
A345883434
10_1038_ijo_2012_197
23229740
27701833
Genre Research Support, Non-U.S. Gov't
Journal Article
GrantInformation_xml – fundername: Canadian Institutes of Health Research
GroupedDBID .55
.GJ
29J
36B
39C
5RE
7X2
7X7
8R4
8R5
A8Z
ABDBF
ABOCM
ABUWG
ADBBV
AFFNX
AI.
ALMA_UNASSIGNED_HOLDINGS
ATCPS
AZQEC
B0M
BAWUL
BENPR
BHPHI
BPHCQ
DIK
DWQXO
EAD
EAP
EBC
EBD
EBS
EMB
EMK
EMOBN
EPL
ESTFP
ESX
F5P
FYUFA
GNUQQ
HCIFZ
IAO
IHR
ITC
J5H
M0K
M1P
M2M
MVM
NAO
OK1
Q2X
RNT
RNTTT
SV3
TUS
VH1
WH7
X7M
ZGI
ZXP
~8M
08R
1GH
ABFLS
ABPTK
ACDSR
ADGIM
IQODW
W2D
ZA5
---
-Q-
..I
.L3
.XZ
0R~
1CY
2FS
2WC
3V.
4.4
406
53G
5GY
70F
88E
8AO
8C1
8FE
8FH
8FI
8FJ
AACDK
AAHBH
AANZL
AASML
AATNV
AAWBL
AAWTL
AAYZH
AAZLF
ABAKF
ABAWZ
ABCQX
ABIVO
ABJNI
ABLJU
ABZZP
ACAOD
ACGFS
ACKTT
ACPRK
ACRQY
ACZOJ
ADHDB
ADHUB
AEFQL
AEJRE
AEMSY
AENEX
AEVLU
AEXYK
AFBBN
AFKRA
AFRAH
AFSHS
AGAYW
AGEZK
AGHAI
AGQEE
AHMBA
AHSBF
AIGIU
AILAN
AJRNO
ALFFA
ALIPV
AMYLF
APEBS
AXYYD
BBNVY
BKKNO
BVXVI
CCPQU
CGR
CS3
CUY
CVF
DNIVK
DPUIP
DU5
E3Z
EBLON
ECM
EE.
EIF
EIOEI
EJD
FDQFY
FERAY
FIGPU
FIZPM
FSGXE
HMCUK
HZ~
IHW
INH
INR
IPY
IWAJR
JSO
JZLTJ
KQ8
L7B
M7P
NPM
NQJWS
O9-
OVD
P2P
P6G
PQQKQ
PROAC
PSQYO
PSYQQ
RNS
SNX
SNYQT
SOHCF
SRMVM
SWTZT
TAOOD
TBHMF
TDRGL
TEORI
TR2
TSG
UKHRP
YCJ
~KM
AAYXX
CITATION
7T2
7TK
7TS
7XB
8FK
C1K
K9.
LK8
PQEST
PQUKI
Q9U
7X8
ID FETCH-LOGICAL-c584t-e184f444cf583f86a43ccfbafddabcf52c7a2871ee1d1592ca479cab574bb9013
IEDL.DBID 7X7
ISSN 0307-0565
IngestDate Fri Oct 25 08:52:10 EDT 2024
Fri Oct 25 06:19:46 EDT 2024
Thu Oct 10 20:51:27 EDT 2024
Thu Feb 22 23:58:47 EST 2024
Fri Feb 02 04:15:34 EST 2024
Tue Aug 20 22:04:43 EDT 2024
Thu Sep 26 19:55:07 EDT 2024
Tue Oct 15 23:43:14 EDT 2024
Thu Nov 24 18:21:07 EST 2022
Fri Oct 11 20:47:10 EDT 2024
IsPeerReviewed true
IsScholarly true
Issue 9
Keywords reward
anxiety
stress
high-fat food
mesolimbic
dopamine
Affect affectivity
Brain
Obesity
Dopamine
Nutrition
Craving
Central nervous system
Nutrition disorder
Anxiety disorder
Metabolic diseases
Catecholamine
Stress
Feeding
Encephalon
Diet
Neurotransmitter
Fat
Anxiety
Reward
Nutritional status
Adaptation
Food
Language English
License CC BY 4.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c584t-e184f444cf583f86a43ccfbafddabcf52c7a2871ee1d1592ca479cab574bb9013
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ObjectType-Article-2
ObjectType-Feature-1
PMID 23229740
PQID 1431087048
PQPubID 38864
PageCount 9
ParticipantIDs proquest_miscellaneous_1439233176
proquest_miscellaneous_1431615076
proquest_journals_1431087048
gale_infotracmisc_A345883434
gale_infotracacademiconefile_A345883434
gale_healthsolutions_A345883434
crossref_primary_10_1038_ijo_2012_197
pubmed_primary_23229740
pascalfrancis_primary_27701833
springer_journals_10_1038_ijo_2012_197
PublicationCentury 2000
PublicationDate 2013-09-01
PublicationDateYYYYMMDD 2013-09-01
PublicationDate_xml – month: 09
  year: 2013
  text: 2013-09-01
  day: 01
PublicationDecade 2010
PublicationPlace London
PublicationPlace_xml – name: London
– name: Basingstoke
– name: England
PublicationTitle International Journal of Obesity
PublicationTitleAbbrev Int J Obes
PublicationTitleAlternate Int J Obes (Lond)
PublicationYear 2013
Publisher Nature Publishing Group UK
Nature Publishing Group
Publisher_xml – name: Nature Publishing Group UK
– name: Nature Publishing Group
References Nair, Navarre, Cifani, Pickens, Bossert, Shaham (CR4) 2011; 36
Geiger, Haburcak, Avena, Moyer, Hoebel, Pothos (CR49) 2009; 159
Goeders, Guerin (CR27) 2000; 23
Bailey, Davis, Lesscher, Kelly, Ledent, Hourani (CR42) 2004; 88
Nestler, Kelz, Chen (CR33) 1999; 835
Koob (CR36) 1999; 897
Li, South, Han, Chen, Wang, Huang (CR12) 2009; 1268
Cottone, Sabino, Roberto, Bajo, Pockros, Frihauf (CR19) 2009; 106
Papp, Willner, Muscat (CR39) 1993; 110
Auvinen, Romijn, Biermasz, Pijl, Havekes, Smit (CR56) 2012; 214
Stice, Yokum, Blum, Bohon (CR52) 2010; 30
Vialou, Robison, LaPlant, Covington, Dietz, Ohnishi (CR64) 2010; 13
Hyman, Malenka, Nestler (CR10) 2006; 29
Pickering, Alsiö, Hulting, Schiöth (CR20) 2009; 204
Graham, Edwards, Bachtell, DiLeone, Rios, Self (CR31) 2007; 10
Smith, Aubry, Dellu, Contarino, Bilezikjian, Gold (CR58) 1998; 20
Zhao, Shi, Zhang, Epstein, Zhang, Liu (CR45) 2010; 35
Shepard, Bossert, Liu, Shaham (CR43) 2004; 55
Edwards, Graham, Bachtell, Self (CR60) 2007; 25
Bale, Picetti, Contarino, Koob, Vale, Lee (CR57) 2002; 22
Ifland, Preuss, Marcus, Rourke, Taylor, Burau (CR5) 2009; 72
Russo, Mazei-Robison, Ables, Nestler (CR34) 2009; 56
Davis, Patte, Levitan, Reid, Tweed, Curtis (CR51) 2007; 48
Carlezon, Thome, Olson, Lane-Ladd, Brodkin, Hiroi (CR59) 1998; 282
Cordeira, Frank, Sena-Esteves, Pothos, Rios (CR62) 2010; 30
Cottone, Sabino, Steardo, Zorrilla (CR17) 2008; 295
Etkin, Prater, Schatzberg, Menon, Greicius (CR8) 2009; 66
Avena, Bocarsly, Rada, Kim, Hoebel (CR40) 2008; 94
Volkow, Wang, Baler (CR54) 2011; 15
Roberto, Cruz, Gilpin, Sabino, Schweitzer, Bajo (CR30) 2010; 67
Stice, Yokum, Burger, Epstein, Small (CR53) 2011; 31
Cottone, Sabino, Steardo, Zorrilla (CR18) 2009; 34
Pandey, Roy, Xu, Mittal (CR61) 2001; 77
Sinha, Fox, Hong, Bergquist, Bhagwagar, Siedlarz (CR44) 2009; 34
Davis, Tracy, Schurdak, Tschop, Lipton, Clegg (CR50) 2008; 122
South, Westbrook, Morris (CR13) 2012; 105
CR15
Gold, Graham, Cocores, Nixon (CR1) 2009; 3
Colantuoni, Rada, McCarthy, Patten, Avena, Chadeayne (CR41) 2002; 10
Fulton (CR6) 2010; 31
Krishnan, Centeno, Pollandt, Fu, Genzer, Liu (CR32) 2010; 31
Richter, Weiss (CR29) 1999; 32
Sarnyai (CR37) 1998; 851
Carlezon, Thomas (CR7) 2009; 56
Carobrez, Bertoglio (CR23) 2005; 29
Koob (CR28) 2009; 1293
Robison, Nestler (CR35) 2011; 12
Nair, Adams-Deutsch, Pickens, Smith, Shaham (CR47) 2009; 205
Papp, Willner, Muscat (CR24) 1991; 104
Nair, Adams-Deutsch, Epstein, Shaham (CR2) 2009; 89
Cottone, Sabino, Steardo, Zorrilla (CR16) 2008; 33
Muscat, Papp, Willner (CR38) 1992; 109
Ghitza, Gray, Epstein, Rice, Shaham (CR3) 2006; 31
Ghitza, Nair, Golden, Gray, Uejima, Bossert (CR46) 2007; 27
Richardson, Roberts (CR21) 1996; 66
Lobo, Covington, Chaudhury, Friedman, Sun, Damez-Werno (CR63) 2010; 330
Tye, Prakash, Kim, Fenno, Grosenick, Zarabi (CR9) 2011; 471
Fulton, Pissios, Manchon, Stiles, Frank, Pothos (CR48) 2006; 51
Teegarden, Bale (CR25) 2007; 61
Jang, Kim, Lee, Moon, Oh (CR55) 2011; 36
Russo, Bolanos, Theobald, DeCarolis, Renthal, Kumar (CR11) 2007; 10
Vucetic, Carlin, Totoki, Reyes (CR14) 2012; 120
George, Ghozland, Azar, Cottone, Zorrilla, Parsons (CR26) 2007; 104
Sharma, Hryhorczuk, Fulton (CR22) 2012; 63
SJ Russo (BFijo2012197_CR34) 2009; 56
S Edwards (BFijo2012197_CR60) 2007; 25
KM Tye (BFijo2012197_CR9) 2011; 471
NM Avena (BFijo2012197_CR40) 2008; 94
WA Carlezon (BFijo2012197_CR7) 2009; 56
WA Carlezon (BFijo2012197_CR59) 1998; 282
M Papp (BFijo2012197_CR24) 1991; 104
V Vialou (BFijo2012197_CR64) 2010; 13
JR Ifland (BFijo2012197_CR5) 2009; 72
C Colantuoni (BFijo2012197_CR41) 2002; 10
R Sinha (BFijo2012197_CR44) 2009; 34
NR Richardson (BFijo2012197_CR21) 1996; 66
O George (BFijo2012197_CR26) 2007; 104
TL Bale (BFijo2012197_CR57) 2002; 22
SE Hyman (BFijo2012197_CR10) 2006; 29
GW Smith (BFijo2012197_CR58) 1998; 20
UE Ghitza (BFijo2012197_CR3) 2006; 31
A Etkin (BFijo2012197_CR8) 2009; 66
E Stice (BFijo2012197_CR53) 2011; 31
JD Shepard (BFijo2012197_CR43) 2004; 55
Y Li (BFijo2012197_CR12) 2009; 1268
GF Koob (BFijo2012197_CR36) 1999; 897
EJ Nestler (BFijo2012197_CR33) 1999; 835
S Sharma (BFijo2012197_CR22) 2012; 63
E Stice (BFijo2012197_CR52) 2010; 30
GF Koob (BFijo2012197_CR28) 2009; 1293
JF Davis (BFijo2012197_CR50) 2008; 122
MS Gold (BFijo2012197_CR1) 2009; 3
LY Zhao (BFijo2012197_CR45) 2010; 35
HE Auvinen (BFijo2012197_CR56) 2012; 214
ND Volkow (BFijo2012197_CR54) 2011; 15
P Cottone (BFijo2012197_CR19) 2009; 106
S Fulton (BFijo2012197_CR48) 2006; 51
P Cottone (BFijo2012197_CR17) 2008; 295
AP Carobrez (BFijo2012197_CR23) 2005; 29
R Muscat (BFijo2012197_CR38) 1992; 109
T South (BFijo2012197_CR13) 2012; 105
Z Sarnyai (BFijo2012197_CR37) 1998; 851
MK Lobo (BFijo2012197_CR63) 2010; 330
NE Goeders (BFijo2012197_CR27) 2000; 23
SG Nair (BFijo2012197_CR47) 2009; 205
SC Pandey (BFijo2012197_CR61) 2001; 77
JW Cordeira (BFijo2012197_CR62) 2010; 30
DL Graham (BFijo2012197_CR31) 2007; 10
S Jang (BFijo2012197_CR55) 2011; 36
P Cottone (BFijo2012197_CR16) 2008; 33
UE Ghitza (BFijo2012197_CR46) 2007; 27
SJ Russo (BFijo2012197_CR11) 2007; 10
SL Teegarden (BFijo2012197_CR25) 2007; 61
SG Nair (BFijo2012197_CR4) 2011; 36
S Fulton (BFijo2012197_CR6) 2010; 31
BFijo2012197_CR15
C Pickering (BFijo2012197_CR20) 2009; 204
B Krishnan (BFijo2012197_CR32) 2010; 31
AJ Robison (BFijo2012197_CR35) 2011; 12
P Cottone (BFijo2012197_CR18) 2009; 34
BM Geiger (BFijo2012197_CR49) 2009; 159
A Bailey (BFijo2012197_CR42) 2004; 88
RM Richter (BFijo2012197_CR29) 1999; 32
SG Nair (BFijo2012197_CR2) 2009; 89
C Davis (BFijo2012197_CR51) 2007; 48
Z Vucetic (BFijo2012197_CR14) 2012; 120
M Roberto (BFijo2012197_CR30) 2010; 67
M Papp (BFijo2012197_CR39) 1993; 110
References_xml – volume: 55
  start-page: 1082
  year: 2004
  end-page: 1089
  ident: CR43
  article-title: The anxiogenic drug yohimbine reinstates methamphetamine seeking in a rat model of drug relapse
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2004.02.032
  contributor:
    fullname: Shaham
– volume: 72
  start-page: 518
  year: 2009
  end-page: 526
  ident: CR5
  article-title: Refined food addiction: a classic substance use disorder
  publication-title: Med Hypotheses
  doi: 10.1016/j.mehy.2008.11.035
  contributor:
    fullname: Burau
– volume: 13
  start-page: 745
  year: 2010
  end-page: 752
  ident: CR64
  article-title: [Delta]FosB in brain reward circuits mediates resilience to stress and antidepressant responses
  publication-title: Nat Neurosci
  doi: 10.1038/nn.2551
  contributor:
    fullname: Ohnishi
– volume: 1268
  start-page: 181
  year: 2009
  end-page: 189
  ident: CR12
  article-title: High-fat diet decreases tyrosine hydroxylase mRNA expression irrespective of obesity susceptibility in mice
  publication-title: Brain Res
  doi: 10.1016/j.brainres.2009.02.075
  contributor:
    fullname: Huang
– volume: 25
  start-page: 2201
  year: 2007
  end-page: 2213
  ident: CR60
  article-title: Region-specific tolerance to cocaine-regulated cAMP-dependent protein phosphorylation following chronic self-administration
  publication-title: Eur J Neurosci
  doi: 10.1111/j.1460-9568.2007.05473.x
  contributor:
    fullname: Self
– volume: 35
  start-page: 720
  year: 2010
  end-page: 726
  ident: CR45
  article-title: Stress enhances retrieval of drug-related memories in abstinent heroin addicts
  publication-title: Neuropsychopharmacology
  doi: 10.1038/npp.2009.179
  contributor:
    fullname: Liu
– volume: 10
  start-page: 93
  year: 2007
  end-page: 99
  ident: CR11
  article-title: IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates
  publication-title: Nat Neurosci
  doi: 10.1038/nn1812
  contributor:
    fullname: Kumar
– volume: 23
  start-page: 577
  year: 2000
  end-page: 586
  ident: CR27
  article-title: Effects of the CRH receptor antagonist CP-154,526 on intravenous cocaine self-administration in rats
  publication-title: Neuropsychopharmacology
  doi: 10.1016/S0893-133X(00)00148-2
  contributor:
    fullname: Guerin
– volume: 66
  start-page: 1
  year: 1996
  end-page: 11
  ident: CR21
  article-title: Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacy
  publication-title: J Neurosci Methods
  doi: 10.1016/0165-0270(95)00153-0
  contributor:
    fullname: Roberts
– volume: 56
  start-page: 122
  issue: Suppl 1
  year: 2009
  end-page: 132
  ident: CR7
  article-title: Biological substrates of reward and aversion: a nucleus accumbens activity hypothesis
  publication-title: Neuropharmacology
  doi: 10.1016/j.neuropharm.2008.06.075
  contributor:
    fullname: Thomas
– volume: 31
  start-page: 4360
  year: 2011
  end-page: 4366
  ident: CR53
  article-title: Youth at risk for obesity show greater activation of striatal and somatosensory regions to food
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.6604-10.2011
  contributor:
    fullname: Small
– volume: 30
  start-page: 13105
  year: 2010
  end-page: 13109
  ident: CR52
  article-title: Weight gain is associated with reduced striatal response to palatable food
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.2105-10.2010
  contributor:
    fullname: Bohon
– volume: 31
  start-page: 1027
  year: 2010
  end-page: 1042
  ident: CR32
  article-title: Dopamine receptor mechanisms mediate corticotropin-releasing factor-induced long-term potentiation in the rat amygdala following cocaine withdrawal
  publication-title: Eur J Neurosci
  doi: 10.1111/j.1460-9568.2010.07148.x
  contributor:
    fullname: Liu
– volume: 51
  start-page: 811
  year: 2006
  end-page: 822
  ident: CR48
  article-title: Leptin regulation of the mesoaccumbens dopamine pathway
  publication-title: Neuron
  doi: 10.1016/j.neuron.2006.09.006
  contributor:
    fullname: Pothos
– volume: 63
  start-page: e3754
  year: 2012
  ident: CR22
  article-title: Progressive-ratio Responding for Palatable High-fat and High-sugar Food inMice
  publication-title: J Vis Exp
  contributor:
    fullname: Fulton
– volume: 36
  start-page: 497
  year: 2011
  end-page: 510
  ident: CR4
  article-title: Role of dorsal medial prefrontal cortex dopamine D1-family receptors in relapse to high-fat food seeking induced by the anxiogenic drug yohimbine
  publication-title: Neuropsychopharmacology
  doi: 10.1038/npp.2010.181
  contributor:
    fullname: Shaham
– ident: CR15
– volume: 88
  start-page: 827
  year: 2004
  end-page: 834
  ident: CR42
  article-title: Enhanced morphine withdrawal and μ-opioid receptor G-protein coupling in A2A adenosine receptor knockout mice
  publication-title: J Neurochem
  doi: 10.1046/j.1471-4159.2003.02214.x
  contributor:
    fullname: Hourani
– volume: 104
  start-page: 255
  year: 1991
  end-page: 259
  ident: CR24
  article-title: An animal model of anhedonia: attenuation of sucrose consumption and place preference conditioning by chronic unpredictable mild stress
  publication-title: Psychopharmacology (Berl)
  doi: 10.1007/BF02244188
  contributor:
    fullname: Muscat
– volume: 205
  start-page: 129
  year: 2009
  end-page: 140
  ident: CR47
  article-title: Effects of the MCH1 receptor antagonist SNAP 94847 on high-fat food-reinforced operant responding and reinstatement of food seeking in rats
  publication-title: Psychopharmacology (Berl)
  doi: 10.1007/s00213-009-1523-6
  contributor:
    fullname: Shaham
– volume: 330
  start-page: 385
  year: 2010
  end-page: 390
  ident: CR63
  article-title: Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward
  publication-title: Science
  doi: 10.1126/science.1188472
  contributor:
    fullname: Damez-Werno
– volume: 204
  start-page: 431
  year: 2009
  end-page: 443
  ident: CR20
  article-title: Withdrawal from free-choice high-fat high-sugar diet induces craving only in obesity-prone animals
  publication-title: Psychopharmacology (Berl)
  doi: 10.1007/s00213-009-1474-y
  contributor:
    fullname: Schiöth
– volume: 897
  start-page: 27
  year: 1999
  end-page: 45
  ident: CR36
  article-title: Stress, corticotropin-releasing factor, and drug addiction
  publication-title: Ann N Y Acad Sci
  doi: 10.1111/j.1749-6632.1999.tb07876.x
  contributor:
    fullname: Koob
– volume: 214
  start-page: 191
  year: 2012
  end-page: 197
  ident: CR56
  article-title: The Effects of high fat diet on the basal activity of the hypothalamus-pituitary-adrenal axis in mice
  publication-title: J Endocrinol
  doi: 10.1530/JOE-12-0056
  contributor:
    fullname: Smit
– volume: 32
  start-page: 254
  year: 1999
  end-page: 261
  ident: CR29
  article-title: CRF release in rat amygdala is increased during cocaine withdrawal in self-administering rats
  publication-title: Synapse
  doi: 10.1002/(SICI)1098-2396(19990615)32:4<254::AID-SYN2>3.0.CO;2-H
  contributor:
    fullname: Weiss
– volume: 471
  start-page: 358
  year: 2011
  end-page: 362
  ident: CR9
  article-title: Amygdala circuitry mediating reversible and bidirectional control of anxiety
  publication-title: Nature
  doi: 10.1038/nature09820
  contributor:
    fullname: Zarabi
– volume: 104
  start-page: 17198
  year: 2007
  end-page: 17203
  ident: CR26
  article-title: CRF-CRF1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.0707585104
  contributor:
    fullname: Parsons
– volume: 29
  start-page: 1193
  year: 2005
  end-page: 1205
  ident: CR23
  article-title: Ethological and temporal analyses of anxiety-like behavior: The elevated plus-maze model 20 years on
  publication-title: Neuroscience & Biobehavioral Reviews
  doi: 10.1016/j.neubiorev.2005.04.017
  contributor:
    fullname: Bertoglio
– volume: 110
  start-page: 159
  year: 1993
  end-page: 164
  ident: CR39
  article-title: Behavioural sensitization to a dopamine agonist is associated with reversal of stress-induced anhedonia
  publication-title: Psychopharmacology (Berl)
  doi: 10.1007/BF02246966
  contributor:
    fullname: Muscat
– volume: 48
  start-page: 12
  year: 2007
  end-page: 19
  ident: CR51
  article-title: From motivation to behaviour: a model of reward sensitivity, overeating, and food preferences in the risk profile for obesity
  publication-title: Appetite
  doi: 10.1016/j.appet.2006.05.016
  contributor:
    fullname: Curtis
– volume: 31
  start-page: 2188
  year: 2006
  end-page: 2196
  ident: CR3
  article-title: The anxiogenic drug yohimbine reinstates palatable food seeking in a rat relapse model: a role of CRF1 receptors
  publication-title: Neuropsychopharmacology
  doi: 10.1038/sj.npp.1300964
  contributor:
    fullname: Shaham
– volume: 10
  start-page: 1029
  year: 2007
  end-page: 1037
  ident: CR31
  article-title: Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse
  publication-title: Nat Neurosci
  doi: 10.1038/nn1929
  contributor:
    fullname: Self
– volume: 835
  start-page: 10
  year: 1999
  end-page: 17
  ident: CR33
  article-title: DeltaFosB: a molecular mediator of long-term neural and behavioral plasticity
  publication-title: Brain Res
  doi: 10.1016/S0006-8993(98)01191-3
  contributor:
    fullname: Chen
– volume: 22
  start-page: 193
  year: 2002
  end-page: 199
  ident: CR57
  article-title: Mice deficient for both corticotropin-releasing factor receptor 1 (crfr1) and crfr2 have an impaired stress response and display sexually dichotomous anxiety-like behavior
  publication-title: The Journal of Neuroscience
  doi: 10.1523/JNEUROSCI.22-01-00193.2002
  contributor:
    fullname: Lee
– volume: 89
  start-page: 18
  year: 2009
  end-page: 45
  ident: CR2
  article-title: The neuropharmacology of relapse to food seeking: methodology, main findings, and comparison with relapse to drug seeking
  publication-title: Prog Neurobiol
  doi: 10.1016/j.pneurobio.2009.05.003
  contributor:
    fullname: Shaham
– volume: 20
  start-page: 1093
  year: 1998
  end-page: 1102
  ident: CR58
  article-title: Corticotropin releasing factor receptor 1–deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development
  publication-title: Neuron
  doi: 10.1016/S0896-6273(00)80491-2
  contributor:
    fullname: Gold
– volume: 29
  start-page: 565
  year: 2006
  end-page: 598
  ident: CR10
  article-title: Neural mechanisms of addiction: the role of reward-related learning and memory
  publication-title: Annu Rev Neurosci
  doi: 10.1146/annurev.neuro.29.051605.113009
  contributor:
    fullname: Nestler
– volume: 851
  start-page: 371
  year: 1998
  end-page: 387
  ident: CR37
  article-title: Neurobiology of stress and cocaine addiction. Studies on corticotropin-releasing factor in rats, monkeys, and humans
  publication-title: Ann N Y Acad Sci
  doi: 10.1111/j.1749-6632.1998.tb09011.x
  contributor:
    fullname: Sarnyai
– volume: 120
  start-page: 891
  year: 2012
  end-page: 898
  ident: CR14
  article-title: Epigenetic dysregulation of the dopamine system in diet-induced obesity
  publication-title: J Neurochem
  contributor:
    fullname: Reyes
– volume: 1293
  start-page: 61
  year: 2009
  end-page: 75
  ident: CR28
  article-title: Brain stress systems in the amygdala and addiction
  publication-title: Brain Res
  doi: 10.1016/j.brainres.2009.03.038
  contributor:
    fullname: Koob
– volume: 36
  start-page: 258
  year: 2011
  end-page: 267
  ident: CR55
  article-title: Modulation of Sphingosine 1-Phosphate and Tyrosine Hydroxylase in the Stress-Induced Anxiety
  publication-title: Neurochem Res
  doi: 10.1007/s11064-010-0313-1
  contributor:
    fullname: Oh
– volume: 295
  start-page: R1066
  year: 2008
  end-page: R1076
  ident: CR17
  article-title: Intermittent access to preferred food reduces the reinforcing efficacy of chow in rats
  publication-title: Am J Physiol Regul Integr Comp Physiol
  doi: 10.1152/ajpregu.90309.2008
  contributor:
    fullname: Zorrilla
– volume: 3
  start-page: 42
  year: 2009
  end-page: 45
  ident: CR1
  article-title: Food addiction?
  publication-title: J Addict Med
  doi: 10.1097/ADM.0b013e318199cd20
  contributor:
    fullname: Nixon
– volume: 109
  start-page: 433
  year: 1992
  end-page: 438
  ident: CR38
  article-title: Reversal of stress-induced anhedonia by the atypical antidepressants, fluoxetine and maprotiline
  publication-title: Psychopharmacology (Berl)
  doi: 10.1007/BF02247719
  contributor:
    fullname: Willner
– volume: 34
  start-page: 38
  year: 2009
  end-page: 49
  ident: CR18
  article-title: Consummatory, anxiety-related and metabolic adaptations in female rats with alternating access to preferred food
  publication-title: Psychoneuroendocrinology
  doi: 10.1016/j.psyneuen.2008.08.010
  contributor:
    fullname: Zorrilla
– volume: 12
  start-page: 623
  year: 2011
  end-page: 637
  ident: CR35
  article-title: Transcriptional and epigenetic mechanisms of addiction
  publication-title: Nat Rev Neurosci
  doi: 10.1038/nrn3111
  contributor:
    fullname: Nestler
– volume: 30
  start-page: 2533
  year: 2010
  end-page: 2541
  ident: CR62
  article-title: Brain-derived neurotrophic factor regulates hedonic feeding by acting on the mesolimbic dopamine system
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.5768-09.2010
  contributor:
    fullname: Rios
– volume: 159
  start-page: 1193
  year: 2009
  end-page: 1199
  ident: CR49
  article-title: Deficits of mesolimbic dopamine neurotransmission in rat dietary obesity
  publication-title: Neuroscience
  doi: 10.1016/j.neuroscience.2009.02.007
  contributor:
    fullname: Pothos
– volume: 105
  start-page: 1052
  year: 2012
  end-page: 1057
  ident: CR13
  article-title: Neurological and stress related effects of shifting obese rats from a palatable diet to chow and lean rats from chow to a palatable diet
  publication-title: Physiol Behav
  doi: 10.1016/j.physbeh.2011.11.019
  contributor:
    fullname: Morris
– volume: 67
  start-page: 831
  year: 2010
  end-page: 839
  ident: CR30
  article-title: Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release plays a key role in alcohol dependence
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2009.11.007
  contributor:
    fullname: Bajo
– volume: 27
  start-page: 11522
  year: 2007
  end-page: 11532
  ident: CR46
  article-title: Peptide YY3-36 decreases reinstatement of high-fat food seeking during dieting in a rat relapse model
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.5405-06.2007
  contributor:
    fullname: Bossert
– volume: 10
  start-page: 478
  year: 2002
  end-page: 488
  ident: CR41
  article-title: Evidence that intermittent, excessive sugar intake causes endogenous opioid dependence
  publication-title: Obesity
  doi: 10.1038/oby.2002.66
  contributor:
    fullname: Chadeayne
– volume: 122
  start-page: 1257
  year: 2008
  end-page: 1263
  ident: CR50
  article-title: Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat
  publication-title: Behav Neurosci
  doi: 10.1037/a0013111
  contributor:
    fullname: Clegg
– volume: 31
  start-page: 85
  year: 2010
  end-page: 103
  ident: CR6
  article-title: Appetite and reward
  publication-title: Front Neuroendocrinol
  doi: 10.1016/j.yfrne.2009.10.003
  contributor:
    fullname: Fulton
– volume: 77
  start-page: 943
  year: 2001
  end-page: 952
  ident: CR61
  article-title: Effects of protracted nicotine exposure and withdrawal on the expression and phosphorylation of the CREB gene transcription factor in rat brain
  publication-title: J Neurochem
  doi: 10.1046/j.1471-4159.2001.00309.x
  contributor:
    fullname: Mittal
– volume: 34
  start-page: 1198
  year: 2009
  end-page: 1208
  ident: CR44
  article-title: Enhanced negative emotion and alcohol craving, and altered physiological responses following stress and cue exposure in alcohol dependent individuals
  publication-title: Neuropsychopharmacology
  doi: 10.1038/npp.2008.78
  contributor:
    fullname: Siedlarz
– volume: 56
  start-page: 73
  issue: Suppl 1
  year: 2009
  end-page: 82
  ident: CR34
  article-title: Neurotrophic factors and structural plasticity in addiction
  publication-title: Neuropharmacology
  doi: 10.1016/j.neuropharm.2008.06.059
  contributor:
    fullname: Nestler
– volume: 66
  start-page: 1361
  year: 2009
  end-page: 1372
  ident: CR8
  article-title: Disrupted amygdalar subregion functional connectivity and evidence of a compensatory network in generalized anxiety disorder
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archgenpsychiatry.2009.104
  contributor:
    fullname: Greicius
– volume: 282
  start-page: 2272
  year: 1998
  end-page: 2275
  ident: CR59
  article-title: Regulation of cocaine reward by CREB
  publication-title: Science
  doi: 10.1126/science.282.5397.2272
  contributor:
    fullname: Hiroi
– volume: 33
  start-page: 524
  year: 2008
  end-page: 535
  ident: CR16
  article-title: Opioid-dependent anticipatory negative contrast and binge-like eating in rats with limited access to highly preferred food
  publication-title: Neuropsychopharmacology
  doi: 10.1038/sj.npp.1301430
  contributor:
    fullname: Zorrilla
– volume: 61
  start-page: 1021
  year: 2007
  end-page: 1029
  ident: CR25
  article-title: Decreases in Dietary Preference Produce Increased Emotionality and Risk for Dietary Relapse
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2006.09.032
  contributor:
    fullname: Bale
– volume: 94
  start-page: 309
  year: 2008
  end-page: 315
  ident: CR40
  article-title: After daily bingeing on a sucrose solution, food deprivation induces anxiety and accumbens dopamine/acetylcholine imbalance
  publication-title: Physiol Behav
  doi: 10.1016/j.physbeh.2008.01.008
  contributor:
    fullname: Hoebel
– volume: 106
  start-page: 20016
  year: 2009
  end-page: 20020
  ident: CR19
  article-title: CRF system recruitment mediates dark side of compulsive eating
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.0908789106
  contributor:
    fullname: Frihauf
– volume: 15
  start-page: 37
  year: 2011
  end-page: 46
  ident: CR54
  article-title: Reward, dopamine and the control of food intake: implications for obesity
  publication-title: Trends Cogn Sci
  doi: 10.1016/j.tics.2010.11.001
  contributor:
    fullname: Baler
– volume: 36
  start-page: 497
  year: 2011
  ident: BFijo2012197_CR4
  publication-title: Neuropsychopharmacology
  doi: 10.1038/npp.2010.181
  contributor:
    fullname: SG Nair
– volume: 15
  start-page: 37
  year: 2011
  ident: BFijo2012197_CR54
  publication-title: Trends Cogn Sci
  doi: 10.1016/j.tics.2010.11.001
  contributor:
    fullname: ND Volkow
– volume: 330
  start-page: 385
  year: 2010
  ident: BFijo2012197_CR63
  publication-title: Science
  doi: 10.1126/science.1188472
  contributor:
    fullname: MK Lobo
– volume: 89
  start-page: 18
  year: 2009
  ident: BFijo2012197_CR2
  publication-title: Prog Neurobiol
  doi: 10.1016/j.pneurobio.2009.05.003
  contributor:
    fullname: SG Nair
– volume: 105
  start-page: 1052
  year: 2012
  ident: BFijo2012197_CR13
  publication-title: Physiol Behav
  doi: 10.1016/j.physbeh.2011.11.019
  contributor:
    fullname: T South
– volume: 67
  start-page: 831
  year: 2010
  ident: BFijo2012197_CR30
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2009.11.007
  contributor:
    fullname: M Roberto
– volume: 897
  start-page: 27
  year: 1999
  ident: BFijo2012197_CR36
  publication-title: Ann N Y Acad Sci
  doi: 10.1111/j.1749-6632.1999.tb07876.x
  contributor:
    fullname: GF Koob
– volume: 66
  start-page: 1
  year: 1996
  ident: BFijo2012197_CR21
  publication-title: J Neurosci Methods
  doi: 10.1016/0165-0270(95)00153-0
  contributor:
    fullname: NR Richardson
– volume: 88
  start-page: 827
  year: 2004
  ident: BFijo2012197_CR42
  publication-title: J Neurochem
  doi: 10.1046/j.1471-4159.2003.02214.x
  contributor:
    fullname: A Bailey
– volume: 35
  start-page: 720
  year: 2010
  ident: BFijo2012197_CR45
  publication-title: Neuropsychopharmacology
  doi: 10.1038/npp.2009.179
  contributor:
    fullname: LY Zhao
– volume: 122
  start-page: 1257
  year: 2008
  ident: BFijo2012197_CR50
  publication-title: Behav Neurosci
  doi: 10.1037/a0013111
  contributor:
    fullname: JF Davis
– volume: 851
  start-page: 371
  year: 1998
  ident: BFijo2012197_CR37
  publication-title: Ann N Y Acad Sci
  doi: 10.1111/j.1749-6632.1998.tb09011.x
  contributor:
    fullname: Z Sarnyai
– volume: 282
  start-page: 2272
  year: 1998
  ident: BFijo2012197_CR59
  publication-title: Science
  doi: 10.1126/science.282.5397.2272
  contributor:
    fullname: WA Carlezon
– volume: 77
  start-page: 943
  year: 2001
  ident: BFijo2012197_CR61
  publication-title: J Neurochem
  doi: 10.1046/j.1471-4159.2001.00309.x
  contributor:
    fullname: SC Pandey
– volume: 61
  start-page: 1021
  year: 2007
  ident: BFijo2012197_CR25
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2006.09.032
  contributor:
    fullname: SL Teegarden
– volume: 51
  start-page: 811
  year: 2006
  ident: BFijo2012197_CR48
  publication-title: Neuron
  doi: 10.1016/j.neuron.2006.09.006
  contributor:
    fullname: S Fulton
– volume: 120
  start-page: 891
  year: 2012
  ident: BFijo2012197_CR14
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.2012.07649.x
  contributor:
    fullname: Z Vucetic
– volume: 1268
  start-page: 181
  year: 2009
  ident: BFijo2012197_CR12
  publication-title: Brain Res
  doi: 10.1016/j.brainres.2009.02.075
  contributor:
    fullname: Y Li
– volume: 56
  start-page: 122
  issue: Suppl 1
  year: 2009
  ident: BFijo2012197_CR7
  publication-title: Neuropharmacology
  doi: 10.1016/j.neuropharm.2008.06.075
  contributor:
    fullname: WA Carlezon
– volume: 29
  start-page: 1193
  year: 2005
  ident: BFijo2012197_CR23
  publication-title: Neuroscience & Biobehavioral Reviews
  doi: 10.1016/j.neubiorev.2005.04.017
  contributor:
    fullname: AP Carobrez
– volume: 29
  start-page: 565
  year: 2006
  ident: BFijo2012197_CR10
  publication-title: Annu Rev Neurosci
  doi: 10.1146/annurev.neuro.29.051605.113009
  contributor:
    fullname: SE Hyman
– volume: 110
  start-page: 159
  year: 1993
  ident: BFijo2012197_CR39
  publication-title: Psychopharmacology (Berl)
  doi: 10.1007/BF02246966
  contributor:
    fullname: M Papp
– volume: 22
  start-page: 193
  year: 2002
  ident: BFijo2012197_CR57
  publication-title: The Journal of Neuroscience
  doi: 10.1523/JNEUROSCI.22-01-00193.2002
  contributor:
    fullname: TL Bale
– volume: 30
  start-page: 2533
  year: 2010
  ident: BFijo2012197_CR62
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.5768-09.2010
  contributor:
    fullname: JW Cordeira
– volume: 10
  start-page: 93
  year: 2007
  ident: BFijo2012197_CR11
  publication-title: Nat Neurosci
  doi: 10.1038/nn1812
  contributor:
    fullname: SJ Russo
– volume: 109
  start-page: 433
  year: 1992
  ident: BFijo2012197_CR38
  publication-title: Psychopharmacology (Berl)
  doi: 10.1007/BF02247719
  contributor:
    fullname: R Muscat
– volume: 32
  start-page: 254
  year: 1999
  ident: BFijo2012197_CR29
  publication-title: Synapse
  doi: 10.1002/(SICI)1098-2396(19990615)32:4<254::AID-SYN2>3.0.CO;2-H
  contributor:
    fullname: RM Richter
– volume: 31
  start-page: 85
  year: 2010
  ident: BFijo2012197_CR6
  publication-title: Front Neuroendocrinol
  doi: 10.1016/j.yfrne.2009.10.003
  contributor:
    fullname: S Fulton
– volume: 31
  start-page: 1027
  year: 2010
  ident: BFijo2012197_CR32
  publication-title: Eur J Neurosci
  doi: 10.1111/j.1460-9568.2010.07148.x
  contributor:
    fullname: B Krishnan
– volume: 10
  start-page: 478
  year: 2002
  ident: BFijo2012197_CR41
  publication-title: Obesity
  doi: 10.1038/oby.2002.66
  contributor:
    fullname: C Colantuoni
– ident: BFijo2012197_CR15
– volume: 48
  start-page: 12
  year: 2007
  ident: BFijo2012197_CR51
  publication-title: Appetite
  doi: 10.1016/j.appet.2006.05.016
  contributor:
    fullname: C Davis
– volume: 13
  start-page: 745
  year: 2010
  ident: BFijo2012197_CR64
  publication-title: Nat Neurosci
  doi: 10.1038/nn.2551
  contributor:
    fullname: V Vialou
– volume: 10
  start-page: 1029
  year: 2007
  ident: BFijo2012197_CR31
  publication-title: Nat Neurosci
  doi: 10.1038/nn1929
  contributor:
    fullname: DL Graham
– volume: 25
  start-page: 2201
  year: 2007
  ident: BFijo2012197_CR60
  publication-title: Eur J Neurosci
  doi: 10.1111/j.1460-9568.2007.05473.x
  contributor:
    fullname: S Edwards
– volume: 205
  start-page: 129
  year: 2009
  ident: BFijo2012197_CR47
  publication-title: Psychopharmacology (Berl)
  doi: 10.1007/s00213-009-1523-6
  contributor:
    fullname: SG Nair
– volume: 34
  start-page: 1198
  year: 2009
  ident: BFijo2012197_CR44
  publication-title: Neuropsychopharmacology
  doi: 10.1038/npp.2008.78
  contributor:
    fullname: R Sinha
– volume: 20
  start-page: 1093
  year: 1998
  ident: BFijo2012197_CR58
  publication-title: Neuron
  doi: 10.1016/S0896-6273(00)80491-2
  contributor:
    fullname: GW Smith
– volume: 204
  start-page: 431
  year: 2009
  ident: BFijo2012197_CR20
  publication-title: Psychopharmacology (Berl)
  doi: 10.1007/s00213-009-1474-y
  contributor:
    fullname: C Pickering
– volume: 104
  start-page: 255
  year: 1991
  ident: BFijo2012197_CR24
  publication-title: Psychopharmacology (Berl)
  doi: 10.1007/BF02244188
  contributor:
    fullname: M Papp
– volume: 94
  start-page: 309
  year: 2008
  ident: BFijo2012197_CR40
  publication-title: Physiol Behav
  doi: 10.1016/j.physbeh.2008.01.008
  contributor:
    fullname: NM Avena
– volume: 471
  start-page: 358
  year: 2011
  ident: BFijo2012197_CR9
  publication-title: Nature
  doi: 10.1038/nature09820
  contributor:
    fullname: KM Tye
– volume: 23
  start-page: 577
  year: 2000
  ident: BFijo2012197_CR27
  publication-title: Neuropsychopharmacology
  doi: 10.1016/S0893-133X(00)00148-2
  contributor:
    fullname: NE Goeders
– volume: 3
  start-page: 42
  year: 2009
  ident: BFijo2012197_CR1
  publication-title: J Addict Med
  doi: 10.1097/ADM.0b013e318199cd20
  contributor:
    fullname: MS Gold
– volume: 66
  start-page: 1361
  year: 2009
  ident: BFijo2012197_CR8
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archgenpsychiatry.2009.104
  contributor:
    fullname: A Etkin
– volume: 63
  start-page: e3754
  year: 2012
  ident: BFijo2012197_CR22
  publication-title: J Vis Exp
  contributor:
    fullname: S Sharma
– volume: 36
  start-page: 258
  year: 2011
  ident: BFijo2012197_CR55
  publication-title: Neurochem Res
  doi: 10.1007/s11064-010-0313-1
  contributor:
    fullname: S Jang
– volume: 159
  start-page: 1193
  year: 2009
  ident: BFijo2012197_CR49
  publication-title: Neuroscience
  doi: 10.1016/j.neuroscience.2009.02.007
  contributor:
    fullname: BM Geiger
– volume: 56
  start-page: 73
  issue: Suppl 1
  year: 2009
  ident: BFijo2012197_CR34
  publication-title: Neuropharmacology
  doi: 10.1016/j.neuropharm.2008.06.059
  contributor:
    fullname: SJ Russo
– volume: 27
  start-page: 11522
  year: 2007
  ident: BFijo2012197_CR46
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.5405-06.2007
  contributor:
    fullname: UE Ghitza
– volume: 295
  start-page: R1066
  year: 2008
  ident: BFijo2012197_CR17
  publication-title: Am J Physiol Regul Integr Comp Physiol
  doi: 10.1152/ajpregu.90309.2008
  contributor:
    fullname: P Cottone
– volume: 1293
  start-page: 61
  year: 2009
  ident: BFijo2012197_CR28
  publication-title: Brain Res
  doi: 10.1016/j.brainres.2009.03.038
  contributor:
    fullname: GF Koob
– volume: 31
  start-page: 2188
  year: 2006
  ident: BFijo2012197_CR3
  publication-title: Neuropsychopharmacology
  doi: 10.1038/sj.npp.1300964
  contributor:
    fullname: UE Ghitza
– volume: 214
  start-page: 191
  year: 2012
  ident: BFijo2012197_CR56
  publication-title: J Endocrinol
  doi: 10.1530/JOE-12-0056
  contributor:
    fullname: HE Auvinen
– volume: 72
  start-page: 518
  year: 2009
  ident: BFijo2012197_CR5
  publication-title: Med Hypotheses
  doi: 10.1016/j.mehy.2008.11.035
  contributor:
    fullname: JR Ifland
– volume: 55
  start-page: 1082
  year: 2004
  ident: BFijo2012197_CR43
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2004.02.032
  contributor:
    fullname: JD Shepard
– volume: 34
  start-page: 38
  year: 2009
  ident: BFijo2012197_CR18
  publication-title: Psychoneuroendocrinology
  doi: 10.1016/j.psyneuen.2008.08.010
  contributor:
    fullname: P Cottone
– volume: 835
  start-page: 10
  year: 1999
  ident: BFijo2012197_CR33
  publication-title: Brain Res
  doi: 10.1016/S0006-8993(98)01191-3
  contributor:
    fullname: EJ Nestler
– volume: 12
  start-page: 623
  year: 2011
  ident: BFijo2012197_CR35
  publication-title: Nat Rev Neurosci
  doi: 10.1038/nrn3111
  contributor:
    fullname: AJ Robison
– volume: 30
  start-page: 13105
  year: 2010
  ident: BFijo2012197_CR52
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.2105-10.2010
  contributor:
    fullname: E Stice
– volume: 33
  start-page: 524
  year: 2008
  ident: BFijo2012197_CR16
  publication-title: Neuropsychopharmacology
  doi: 10.1038/sj.npp.1301430
  contributor:
    fullname: P Cottone
– volume: 106
  start-page: 20016
  year: 2009
  ident: BFijo2012197_CR19
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.0908789106
  contributor:
    fullname: P Cottone
– volume: 104
  start-page: 17198
  year: 2007
  ident: BFijo2012197_CR26
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.0707585104
  contributor:
    fullname: O George
– volume: 31
  start-page: 4360
  year: 2011
  ident: BFijo2012197_CR53
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.6604-10.2011
  contributor:
    fullname: E Stice
SSID ssj0005502
ssj0033214
Score 2.512669
Snippet Objective: To identify the emotional and motivational processes that reinstate palatable food intake following removal of high-fat diet (HFD) and associated...
To identify the emotional and motivational processes that reinstate palatable food intake following removal of high-fat diet (HFD) and associated...
OBJECTIVE: To identify the emotional and motivational processes that reinstate palatable food intake following removal of high-fat diet (HFD) and associated...
International Journal of Obesity (2013) 37, 1183-1191; doi: 10.1038/ijo.2012.197; published online 11 December 2012
OBJECTIVETo identify the emotional and motivational processes that reinstate palatable food intake following removal of high-fat diet (HFD) and associated...
Objective: To identify the emotional and motivational processes that reinstate palatable food intake following removal of high-fat diet (HFD) and associated...
SourceID proquest
gale
crossref
pubmed
pascalfrancis
springer
SourceType Aggregation Database
Index Database
Publisher
StartPage 1183
SubjectTerms 631/378/1488/393
631/378/1689/1300
631/378/1689/1831
Animals
Anxiety
Anxiety - metabolism
Anxiety - physiopathology
Behavior, Animal
Biological and medical sciences
Blotting, Western
Brain - metabolism
Brain - physiopathology
Brain stimulation rewards
Brain-Derived Neurotrophic Factor - metabolism
Diet
Diet, High-Fat
Disease Models, Animal
Dopamine - metabolism
Epidemiology
Food
Health Promotion and Disease Prevention
Hypersensitivity
Influence
Internal Medicine
Ketogenic diet
Male
Medical sciences
Medicine
Medicine & Public Health
Metabolic Diseases
Mice
Mice, Inbred C57BL
Motor Activity
Neuronal Plasticity
Obesity
Obesity - etiology
Obesity - metabolism
Obesity - physiopathology
original-article
Physiological aspects
Plasticity
Promoter Regions, Genetic
Psychological aspects
Public Health
Receptors, Corticotropin-Releasing Hormone - metabolism
Reward
Stress, Psychological - metabolism
Stress, Psychological - physiopathology
Sucrose - metabolism
Tyrosine 3-Monooxygenase - metabolism
Title Adaptations in brain reward circuitry underlie palatable food cravings and anxiety induced by high-fat diet withdrawal
URI https://link.springer.com/article/10.1038/ijo.2012.197
https://www.ncbi.nlm.nih.gov/pubmed/23229740
https://www.proquest.com/docview/1431087048
https://search.proquest.com/docview/1431615076
https://search.proquest.com/docview/1439233176
Volume 37
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3da9RAEF-0BRFE9PyK1nMFrU9pk93Nxz3JWVuK4CFi4d7CZj8gciRpkqv2v3cm2dz1sPTh8nCZhCEzO_PbnS9CPsRMmVlqY5xeBhertJ_mVvsK3BWGbcAl9Amyi_j8QnxbRkt34Na6tMrRJvaGWlcKz8iPwa-HASiXSD_Xlz5OjcLoqhuhcZ_shyyIMaUrWSbbFI8o2PSS4jiRZ-yKCF4_clnwAU-Pi99YBhiyoxB7P93wT85KP6plC1_MDqMubsOi_8VRe_d09oQ8driSzgdFeErumXJCvK-F6eghdc0_V3Qx9t6fkAffXVR9QiZb7AjE_dzz9hm5mmtZD4H6lhYlzXGYBG0MptlSVTRqXXTNNcUitAaALK3lSnZYiEVtVQFFI_GsoqWy1PD7i7mh8BoNqqRpfk2xT7JvZUc18ojHwbqRf-TqObk4O_11cu67KQ2-AvDS-Qb2iFYIoWyUcpvGUnClbC6t1jKHP5lKJG7LjAk1YCempEhmSuZRIvIc0Ah_QfbKqjSvCGVKRUwrE0XKijCJZ9JaIRPc9FkmbOyRj6NssnpoxpH1QXSeZiDDDGWYgQw98g4Flw2lpJs1nM051uVywYVHPvUUuIq7RirpihGAD-yHtUN5sEMJq0_t3J7uKMeGL5YA3ynn8PyoLZkzD222VWaPvN_cxldjyltpqvVAg936k_hOGgDoAAGB5uWgiVsGwFTDZjHwyOGomjcYuOWrvb6b0zfkIetHgWB-3QHZ65q1eQuArMun_aqDa3oSTsn-l9PFj5__AItgNG8
link.rule.ids 315,783,787,12068,12235,21400,27936,27937,31731,31732,33278,33279,33756,33757,43322,43591,43817,74073,74342,74630
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3db9NADD_BJgESQlA-FhjbIcF4Cmtyl48-oQKbCmwVQpu0t9PlPqRMVRKSFNh_j51c2lVMe0gfEjeyYt_ZPts_E_I2DpWZpDbG6WXwY5X208xqX4G5wrQNmISuQHYez875t4vowh24Na6sctgTu41alwrPyA_BrgdjUC6efqx--Tg1CrOrboTGXbKNUFUQfG1_Opr_-Lku8ojGKzQphjN5BlxEsPuRq4Mfs_Qwv8RGwCD8ECD60zUL5fbph5Vs4JvZftjFTd7of5nUzkAdPyaPnGdJp70qPCF3TDEi3pfctPSAOvjPBZ0P6Psjcu_U5dVHZLT2HoG4m3zePCW_p1pWfaq-oXlBMxwnQWuDhbZU5bVa5m19RbENrQZXllZyIVtsxaK2LIGilnha0VBZaLj-YnUovEaDMmmaXVFESvatbKlGHvFAWNfyj1w8I-fHR2efZ76b0-ArcF9a30CUaDnnykYps2ksOVPKZtJqLTO4GapEYmBmTKDBewqV5MlEySxKeJaBP8Kek62iLMwOoaFSUaiViSJleZDEE2ktlwmGfTbkNvbIu0E2ourhOESXRmepABkKlKEAGXpkHwUn-mbS1SoWU4aduYwz7pH3HQWu47aWSrp2BOADEbE2KHc3KGH9qY3HexvKseIrTIDvlDH4_6Atwm0QjVirs0ferB7jq7HorTDlsqdBvP4kvpUGXHRwAoHmRa-JawZgs4ZwceyRg0E1rzFww1d7eTun--T-7Oz0RJx8nX9_RR6E3WAQrLbbJVttvTSvwT1rsz23Bv8Be4A2Xg
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Zb9NAEB5BKlVICEG4XEq7SFCe3Dje9ZEnFGijckUVolLfrPUeUlDkpLYD9N8zY6-TRlR9cB7siTXyHPvtzgXwNg6VGaU2pull-GOV9tPcal_hckVhG1wSmgTZaXx2Ib5cRpcu_6lyaZWdT2wctV4oOiMf4Lo-DFC5RDqwLi3i_GTyYXnl0wQpirS6cRr3YScRMQ96sPPxdHr-Y5PwEQXrzlKc5vN0PRIRA0QuJz7g6WD2i4oCh-HxkDpB3VitnM9-uJQVfj_bDr64DZn-F1VtFqvJY3jkUCYbt2rxBO6Zog_eyczU7Ii5VqBzNu068fdh97uLsfehv0GSSNxMQa-ewu-xlss2bF-xWcFyGi3BSkNJt0zNSrWa1eU1o5K0EmEtW8q5rKksi9nFAilKSScXFZOFxusvZYriazQqlmb5NaOuyb6VNdPEIx0O61L-kfNncDE5_fnpzHczG3yFUKb2De4YrRBC2SjlNo2l4ErZXFqtZY43Q5VI2qQZM9SIpEIlRTJSMo8SkeeITfhz6BWLwrwEFioVhVqZKFJWDJN4JK0VMqEtoA2FjT1418kmW7atObImpM7TDGWYkQwzlKEHhyS4rC0sXVt0NuZUpcsFFx68byjIputSKulKE5AP6o61Rbm_RYm2qLYeH2wpx5qvMEG-U87x_522ZM5ZVNlGtT14s35Mr6YEuMIsVi0N9e5P4jtpEK4jIESaF60mbhhAx41bx8CDo041bzBwy1fbu5vTQ9hF88u-fZ5-fQUPwmZGCCXe7UOvLlfmNSK1Oj9wJvgPNjE6jA
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Adaptations+in+brain+reward+circuitry+underlie+palatable+food+cravings+and+anxiety+induced+by+high-fat+diet+withdrawal&rft.jtitle=International+Journal+of+Obesity&rft.au=Sharma%2C+S&rft.au=Fernandes%2C+M+F&rft.au=Fulton%2C+S&rft.date=2013-09-01&rft.issn=0307-0565&rft.eissn=1476-5497&rft.volume=37&rft.issue=9&rft.spage=1183&rft.epage=1191&rft_id=info:doi/10.1038%2Fijo.2012.197&rft.externalDBID=n%2Fa&rft.externalDocID=10_1038_ijo_2012_197
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0307-0565&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0307-0565&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0307-0565&client=summon