Histopathological and immunohistochemical examination of the brains of rabid dogs in the Philippines

• Published in: Journal of Veterinary Medical Science Vol. 86; no. 12; pp. 24-0249 - 1251
• Main Authors: MARKBORDEE, Boonkanit, CABIC, Alpha Grace B, IAMOHBHARS, Nuttipa, SHIWA-SUDO, Nozomi, KIMITSUKI, Kazunori, ESPINO, Mark Joseph M., NACION, Leilanie B., MANALO, Daria Llenarresas, INOUE, Satoshi, PARK, Chun-Ho
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 2024; Japan Science and Technology Agency; The Japanese Society of Veterinary Science
• Subjects: Animals; Antigens, Viral - analysis; Bats; brain; Brain - pathology; Brain - virology; Brain stem; Cerebral cortex; Cerebrum; Cytoplasm; Dog Diseases - pathology; Dog Diseases - virology; Dogs; Female; Hippocampus; Hippocampus - pathology; histopathology; Immunohistochemistry; Immunohistochemistry - veterinary; Inclusion bodies; Inclusion Bodies, Viral; Lyssavirus; Male; Negri bodies; Neuronal-glial interactions; Neuropathology; Pathology; Philippines; Pyramidal cells; rabid dog; Rabies; Rabies - pathology; Rabies - veterinary; Rabies - virology; Rabies virus - isolation & purification; Thalamus; Philippines; histopathology; immunohistochemistry; brain; Philippines; rabid dog

Dogs are the primary transmitters of the rabies virus in the Philippines; however, to the best of our knowledge, no published studies have examined its detailed neuropathology. The present study analyzed the neuropathology in the cerebrum, hippocampus, thalamus, and brainstem of 70 rabid dogs with c...