Auricular acupressure for myopia prevention and control in children and its effect on choroid and retina: a randomized controlled trial protocol
Background Nowadays, because of the increasing incidence, the prevention and control of myopia has become an urgent issue. In China, auricular acupressure has been commonly used in the clinical treatment of myopia in children, but the exact effectiveness remains unproven. The purpose of this trial i...
Saved in:
| Published in | Current controlled trials in cardiovascular medicine Vol. 22; no. 1; pp. 387 - 8 |
|---|---|
| Main Authors | , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
London
BioMed Central
07.06.2021
BioMed Central Ltd BMC |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1745-6215 1745-6215 |
| DOI | 10.1186/s13063-021-05334-1 |
Cover
| Abstract | Background
Nowadays, because of the increasing incidence, the prevention and control of myopia has become an urgent issue. In China, auricular acupressure has been commonly used in the clinical treatment of myopia in children, but the exact effectiveness remains unproven. The purpose of this trial is to observe the efficacy of auricular acupressure in myopia prevention and control, as well as its effect on the choroidal and retinal thickness.
Method/design
A total of 480 subjects at 8–9 years old will be randomized in a 1:1 ratio to an intervention group versus a control group. The intervention group will receive auricular acupressure for 12 months, while the control group will be taken as a blank control. The primary and secondary outcomes will be measured at baseline, and again at 3, 6, 9, and 12 months after recruitment. The myopia incidence (spherical equivalent ≤ − 0.50 D) and the mean change of spherical equivalent will be taken as the primary variables; the secondary outcome measures include axial length, uncorrected visual acuity, and choroidal and retinal thickness.
Discussion
This trial aims to evaluate the effectiveness of auricular acupressure for myopia prevention and control with objective evidence and to preliminarily explore the plausible mechanism and provide reference for adopting this approach to retard the onset and control the progression of myopia.
Trial registration
Chinese Clinical Trial Registry
ChiCTR2000038456
. Registered on September 23, 2020. |
|---|---|
| AbstractList | BackgroundNowadays, because of the increasing incidence, the prevention and control of myopia has become an urgent issue. In China, auricular acupressure has been commonly used in the clinical treatment of myopia in children, but the exact effectiveness remains unproven. The purpose of this trial is to observe the efficacy of auricular acupressure in myopia prevention and control, as well as its effect on the choroidal and retinal thickness.Method/designA total of 480 subjects at 8–9 years old will be randomized in a 1:1 ratio to an intervention group versus a control group. The intervention group will receive auricular acupressure for 12 months, while the control group will be taken as a blank control. The primary and secondary outcomes will be measured at baseline, and again at 3, 6, 9, and 12 months after recruitment. The myopia incidence (spherical equivalent ≤ − 0.50 D) and the mean change of spherical equivalent will be taken as the primary variables; the secondary outcome measures include axial length, uncorrected visual acuity, and choroidal and retinal thickness.DiscussionThis trial aims to evaluate the effectiveness of auricular acupressure for myopia prevention and control with objective evidence and to preliminarily explore the plausible mechanism and provide reference for adopting this approach to retard the onset and control the progression of myopia.Trial registrationChinese Clinical Trial Registry ChiCTR2000038456. Registered on September 23, 2020. Background Nowadays, because of the increasing incidence, the prevention and control of myopia has become an urgent issue. In China, auricular acupressure has been commonly used in the clinical treatment of myopia in children, but the exact effectiveness remains unproven. The purpose of this trial is to observe the efficacy of auricular acupressure in myopia prevention and control, as well as its effect on the choroidal and retinal thickness. Method/design A total of 480 subjects at 8-9 years old will be randomized in a 1:1 ratio to an intervention group versus a control group. The intervention group will receive auricular acupressure for 12 months, while the control group will be taken as a blank control. The primary and secondary outcomes will be measured at baseline, and again at 3, 6, 9, and 12 months after recruitment. The myopia incidence (spherical equivalent [less than or equai to] - 0.50 D) and the mean change of spherical equivalent will be taken as the primary variables; the secondary outcome measures include axial length, uncorrected visual acuity, and choroidal and retinal thickness. Discussion This trial aims to evaluate the effectiveness of auricular acupressure for myopia prevention and control with objective evidence and to preliminarily explore the plausible mechanism and provide reference for adopting this approach to retard the onset and control the progression of myopia. Trial registration Chinese Clinical Trial Registry ChiCTR2000038456. Registered on September 23, 2020. Keywords: Myopia prevention and control, Auricular acupressure, Randomized clinical trial, Choroid, Retina Abstract Background Nowadays, because of the increasing incidence, the prevention and control of myopia has become an urgent issue. In China, auricular acupressure has been commonly used in the clinical treatment of myopia in children, but the exact effectiveness remains unproven. The purpose of this trial is to observe the efficacy of auricular acupressure in myopia prevention and control, as well as its effect on the choroidal and retinal thickness. Method/design A total of 480 subjects at 8–9 years old will be randomized in a 1:1 ratio to an intervention group versus a control group. The intervention group will receive auricular acupressure for 12 months, while the control group will be taken as a blank control. The primary and secondary outcomes will be measured at baseline, and again at 3, 6, 9, and 12 months after recruitment. The myopia incidence (spherical equivalent ≤ − 0.50 D) and the mean change of spherical equivalent will be taken as the primary variables; the secondary outcome measures include axial length, uncorrected visual acuity, and choroidal and retinal thickness. Discussion This trial aims to evaluate the effectiveness of auricular acupressure for myopia prevention and control with objective evidence and to preliminarily explore the plausible mechanism and provide reference for adopting this approach to retard the onset and control the progression of myopia. Trial registration Chinese Clinical Trial Registry ChiCTR2000038456 . Registered on September 23, 2020. Background Nowadays, because of the increasing incidence, the prevention and control of myopia has become an urgent issue. In China, auricular acupressure has been commonly used in the clinical treatment of myopia in children, but the exact effectiveness remains unproven. The purpose of this trial is to observe the efficacy of auricular acupressure in myopia prevention and control, as well as its effect on the choroidal and retinal thickness. Method/design A total of 480 subjects at 8–9 years old will be randomized in a 1:1 ratio to an intervention group versus a control group. The intervention group will receive auricular acupressure for 12 months, while the control group will be taken as a blank control. The primary and secondary outcomes will be measured at baseline, and again at 3, 6, 9, and 12 months after recruitment. The myopia incidence (spherical equivalent ≤ − 0.50 D) and the mean change of spherical equivalent will be taken as the primary variables; the secondary outcome measures include axial length, uncorrected visual acuity, and choroidal and retinal thickness. Discussion This trial aims to evaluate the effectiveness of auricular acupressure for myopia prevention and control with objective evidence and to preliminarily explore the plausible mechanism and provide reference for adopting this approach to retard the onset and control the progression of myopia. Trial registration Chinese Clinical Trial Registry ChiCTR2000038456 . Registered on September 23, 2020. Nowadays, because of the increasing incidence, the prevention and control of myopia has become an urgent issue. In China, auricular acupressure has been commonly used in the clinical treatment of myopia in children, but the exact effectiveness remains unproven. The purpose of this trial is to observe the efficacy of auricular acupressure in myopia prevention and control, as well as its effect on the choroidal and retinal thickness. A total of 480 subjects at 8-9 years old will be randomized in a 1:1 ratio to an intervention group versus a control group. The intervention group will receive auricular acupressure for 12 months, while the control group will be taken as a blank control. The primary and secondary outcomes will be measured at baseline, and again at 3, 6, 9, and 12 months after recruitment. The myopia incidence (spherical equivalent [less than or equai to] - 0.50 D) and the mean change of spherical equivalent will be taken as the primary variables; the secondary outcome measures include axial length, uncorrected visual acuity, and choroidal and retinal thickness. This trial aims to evaluate the effectiveness of auricular acupressure for myopia prevention and control with objective evidence and to preliminarily explore the plausible mechanism and provide reference for adopting this approach to retard the onset and control the progression of myopia. Nowadays, because of the increasing incidence, the prevention and control of myopia has become an urgent issue. In China, auricular acupressure has been commonly used in the clinical treatment of myopia in children, but the exact effectiveness remains unproven. The purpose of this trial is to observe the efficacy of auricular acupressure in myopia prevention and control, as well as its effect on the choroidal and retinal thickness.BACKGROUNDNowadays, because of the increasing incidence, the prevention and control of myopia has become an urgent issue. In China, auricular acupressure has been commonly used in the clinical treatment of myopia in children, but the exact effectiveness remains unproven. The purpose of this trial is to observe the efficacy of auricular acupressure in myopia prevention and control, as well as its effect on the choroidal and retinal thickness.A total of 480 subjects at 8-9 years old will be randomized in a 1:1 ratio to an intervention group versus a control group. The intervention group will receive auricular acupressure for 12 months, while the control group will be taken as a blank control. The primary and secondary outcomes will be measured at baseline, and again at 3, 6, 9, and 12 months after recruitment. The myopia incidence (spherical equivalent ≤ - 0.50 D) and the mean change of spherical equivalent will be taken as the primary variables; the secondary outcome measures include axial length, uncorrected visual acuity, and choroidal and retinal thickness.METHOD/DESIGNA total of 480 subjects at 8-9 years old will be randomized in a 1:1 ratio to an intervention group versus a control group. The intervention group will receive auricular acupressure for 12 months, while the control group will be taken as a blank control. The primary and secondary outcomes will be measured at baseline, and again at 3, 6, 9, and 12 months after recruitment. The myopia incidence (spherical equivalent ≤ - 0.50 D) and the mean change of spherical equivalent will be taken as the primary variables; the secondary outcome measures include axial length, uncorrected visual acuity, and choroidal and retinal thickness.This trial aims to evaluate the effectiveness of auricular acupressure for myopia prevention and control with objective evidence and to preliminarily explore the plausible mechanism and provide reference for adopting this approach to retard the onset and control the progression of myopia.DISCUSSIONThis trial aims to evaluate the effectiveness of auricular acupressure for myopia prevention and control with objective evidence and to preliminarily explore the plausible mechanism and provide reference for adopting this approach to retard the onset and control the progression of myopia.Chinese Clinical Trial Registry ChiCTR2000038456 . Registered on September 23, 2020.TRIAL REGISTRATIONChinese Clinical Trial Registry ChiCTR2000038456 . Registered on September 23, 2020. |
| ArticleNumber | 387 |
| Audience | Academic |
| Author | Chen, Zhi Zeng, Li Han, Rong Zhao, Yue Yang, Guang Zhao, Feng Hong, Jue Yang, Yan-ting Dong, Xiao-qing Zhou, Xing-tao Kong, Xie-he Ma, Xiao-peng |
| Author_xml | – sequence: 1 givenname: Rong surname: Han fullname: Han, Rong organization: Shanghai University of Traditional Chinese Medicine – sequence: 2 givenname: Xie-he surname: Kong fullname: Kong, Xie-he organization: Shanghai Research Institute of Acupuncture and Meridian – sequence: 3 givenname: Feng surname: Zhao fullname: Zhao, Feng organization: Department of Ophthalmology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine – sequence: 4 givenname: Yan-ting surname: Yang fullname: Yang, Yan-ting organization: Shanghai Research Institute of Acupuncture and Meridian – sequence: 5 givenname: Xiao-qing surname: Dong fullname: Dong, Xiao-qing organization: Shanghai University of Traditional Chinese Medicine – sequence: 6 givenname: Li surname: Zeng fullname: Zeng, Li organization: Department of Ophthalmology, Eye and ENT Hospital of Fudan University – sequence: 7 givenname: Zhi surname: Chen fullname: Chen, Zhi organization: Department of Ophthalmology, Eye and ENT Hospital of Fudan University – sequence: 8 givenname: Yue surname: Zhao fullname: Zhao, Yue organization: Shanghai Research Institute of Acupuncture and Meridian – sequence: 9 givenname: Guang surname: Yang fullname: Yang, Guang organization: Shanghai Research Institute of Acupuncture and Meridian – sequence: 10 givenname: Jue surname: Hong fullname: Hong, Jue organization: Shanghai Research Institute of Acupuncture and Meridian – sequence: 11 givenname: Xing-tao surname: Zhou fullname: Zhou, Xing-tao email: xingtaozhou@163.com organization: Department of Ophthalmology, Eye and ENT Hospital of Fudan University – sequence: 12 givenname: Xiao-peng surname: Ma fullname: Ma, Xiao-peng email: pengpengma@163.com organization: Shanghai University of Traditional Chinese Medicine, Shanghai Research Institute of Acupuncture and Meridian |
| BookMark | eNp9Ustu1DAUjVARfcAPsLLEhk2KX0lsFkijCmilSmxgbTl-TD1y7MF2KpWv4JPxTKq2U6Eqi9j3noeu7zltjkIMpmneI3iOEOs_ZURgT1qIUQs7QmiLXjUnaKBd22PUHT05HzenOW8gpIQT-qY5JhRyDhE7af6u5uTU7GUCUs3bZHKekwE2JjDdxa2ToNZuTSguBiCDBiqGkqIHLgB147xOZqm7koGx1qgC4q4VU3R630mmuCA_AwlSvcbJ_TEPMr4eS3LSV5tYoor-bfPaSp_Nu_v_WfPr29efF5ft9Y_vVxer61Z1jJaWU0W4lVxpKa22WFna90QPnIyUI6oRJ4yNUlmmGIdkwIyZUbMRWYqJHjU5a64WXR3lRmyTm2S6E1E6sS_EtBYyFae8EbDnWCJOcTcOVFbXjtjeQKrsqLAaaNX6smht53EyWtXnStIfiB52grsR63grWF0jgjuBj_cCKf6eTS5iclkZ72Uwcc4Cd4RjyDDEFfrhGXQT5xTqUwk8EFg329PhEbWWdQAXbKy-aicqVn3fUUw7Civq_D-o-mkzubohY12tHxDwQlAp5pyMfZgRQbHLpFgyKWomxT6TAlUSe0ZSrshdoKqb8y9TyULN1SesTXoc9gXWPycF-Is |
| CitedBy_id | crossref_primary_10_1167_iovs_64_6_7 crossref_primary_10_1155_2022_9208478 crossref_primary_10_33546_bnj_3524 |
| Cites_doi | 10.1167/iovs.14-15737 10.1038/srep28531 10.1038/srep34936 10.1016/j.ophtha.2019.12.011 10.1097/IAE.0000000000002590 10.1167/iovs.06-1118 10.1016/j.exer.2013.03.008 10.1167/iovs.18-25957 10.2147/OPTH.S241435 10.1016/j.ophtha.2015.07.004 10.1136/bjophthalmol-2018-312573 10.1016/j.preteyeres.2009.12.002 10.1016/j.autneu.2007.10.003 10.1016/j.ophtha.2012.12.018 10.3390/medicines5030095 10.1167/iovs.06-0426 10.1016/j.ophtha.2018.05.029 10.1167/iovs.18-25958 10.1016/0042-6989(94)E0049-Q 10.1016/j.ophtha.2012.11.009 10.1371/journal.pone.0082763 10.1136/bjophthalmol-2019-315440 10.1016/j.ctcp.2019.101067 10.1136/bjo.2009.176040 10.1016/j.ctim.2014.03.004 10.1136/bjophthalmol-2020-316475 10.1167/iovs.15-16446 10.1111/aos.12299 10.1586/eop.10.67 10.1016/j.ctim.2008.04.007 10.1007/s00347-011-2497-4 10.1167/iovs.14-13935 |
| ContentType | Journal Article |
| Copyright | The Author(s) 2021 COPYRIGHT 2021 BioMed Central Ltd. The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: The Author(s) 2021 – notice: COPYRIGHT 2021 BioMed Central Ltd. – notice: The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| DBID | C6C AAYXX CITATION 3V. 7RV 7X7 7XB 88E 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH K9. KB0 M0S M1P NAPCQ PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS 7X8 5PM DOA |
| DOI | 10.1186/s13063-021-05334-1 |
| DatabaseName | Springer Nature OA Free Journals CrossRef ProQuest Central (Corporate) Nursing & Allied Health Database Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central ProQuest One Community College ProQuest Central Korea Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Database (Alumni Edition) ProQuest Health & Medical Collection Medical Database Nursing & Allied Health Premium ProQuest Central Premium ProQuest One Academic (New) Publicly Available Content Database ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef Publicly Available Content Database ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Central China ProQuest Central ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Health & Medical Research Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest One Academic Eastern Edition ProQuest Nursing & Allied Health Source ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest Nursing & Allied Health Source (Alumni) ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | Publicly Available Content Database MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: C6C name: Springer Nature OA Free Journals url: http://www.springeropen.com/ sourceTypes: Publisher – sequence: 2 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 3 dbid: BENPR name: ProQuest Central url: http://www.proquest.com/pqcentral?accountid=15518 sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1745-6215 |
| EndPage | 8 |
| ExternalDocumentID | oai_doaj_org_article_0692a19425b74a9fa53f6e04cfbc2c74 PMC8186104 A665424540 10_1186_s13063_021_05334_1 |
| GeographicLocations | China |
| GeographicLocations_xml | – name: China |
| GrantInformation_xml | – fundername: Shanghai Municipal Health Bureau grantid: 20194Y0210 funderid: http://dx.doi.org/10.13039/501100007279 – fundername: ; grantid: 20194Y0210 |
| GroupedDBID | --- 0R~ 123 2-G 29Q 2WC 53G 5VS 6PF 7RV 7X7 88E 8FI 8FJ AAFWJ AAJSJ AASML AAWTL ABDBF ABUWG ACGFO ACGFS ACUHS ADBBV ADRAZ ADUKV AEGXH AENEX AFKRA AFPKN AHBYD AHYZX AIAGR ALMA_UNASSIGNED_HOLDINGS AMKLP AMTXH AOIJS BAPOH BAWUL BCNDV BENPR BFQNJ BMC C6C CCPQU CS3 DIK DU5 E3Z EBD EBLON EBS EMOBN ESX F5P FYUFA GROUPED_DOAJ GX1 HMCUK HYE IAO IHR INH INR ITC KQ8 M1P M48 M~E NAPCQ O5R O5S OVT PGMZT PHGZM PHGZT PIMPY PJZUB PPXIY PSQYO PUEGO RBZ RNS ROL RPM RSV SMD SOJ SV3 TR2 TUS U2A UKHRP WOQ WOW ~8M AAYXX ALIPV CITATION PMFND 3V. 5GY 7XB 8FK AHMBA AZQEC DWQXO K9. PKEHL PQEST PQQKQ PQUKI PRINS XSB 7X8 5PM |
| ID | FETCH-LOGICAL-c584t-94c39fa9cdaafdf2cf4663d793b4914d19388bacf8c89037288ebd8b1f423dbd3 |
| IEDL.DBID | M48 |
| ISSN | 1745-6215 |
| IngestDate | Wed Aug 27 01:32:23 EDT 2025 Thu Aug 21 14:11:01 EDT 2025 Fri Sep 05 12:51:38 EDT 2025 Fri Jul 25 21:00:30 EDT 2025 Tue Jun 17 21:27:55 EDT 2025 Tue Jun 10 20:40:40 EDT 2025 Thu Apr 24 23:11:01 EDT 2025 Tue Jul 01 04:00:55 EDT 2025 Sat Sep 06 07:26:53 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | Auricular acupressure Myopia prevention and control Choroid Retina Randomized clinical trial |
| Language | English |
| License | Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c584t-94c39fa9cdaafdf2cf4663d793b4914d19388bacf8c89037288ebd8b1f423dbd3 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 content type line 14 ObjectType-Feature-3 ObjectType-Evidence Based Healthcare-1 ObjectType-Undefined-1 content type line 23 |
| OpenAccessLink | http://journals.scholarsportal.info/openUrl.xqy?doi=10.1186/s13063-021-05334-1 |
| PMID | 34099018 |
| PQID | 2730340647 |
| PQPubID | 44365 |
| PageCount | 8 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_0692a19425b74a9fa53f6e04cfbc2c74 pubmedcentral_primary_oai_pubmedcentral_nih_gov_8186104 proquest_miscellaneous_2539208202 proquest_journals_2730340647 gale_infotracmisc_A665424540 gale_infotracacademiconefile_A665424540 crossref_primary_10_1186_s13063_021_05334_1 crossref_citationtrail_10_1186_s13063_021_05334_1 springer_journals_10_1186_s13063_021_05334_1 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2021-06-07 |
| PublicationDateYYYYMMDD | 2021-06-07 |
| PublicationDate_xml | – month: 06 year: 2021 text: 2021-06-07 day: 07 |
| PublicationDecade | 2020 |
| PublicationPlace | London |
| PublicationPlace_xml | – name: London |
| PublicationTitle | Current controlled trials in cardiovascular medicine |
| PublicationTitleAbbrev | Trials |
| PublicationYear | 2021 |
| Publisher | BioMed Central BioMed Central Ltd BMC |
| Publisher_xml | – name: BioMed Central – name: BioMed Central Ltd – name: BMC |
| References | XY Gao (5334_CR40) 2008; 138 A Fu (5334_CR17) 2020; 104 K Guo (5334_CR2) 2015; 56 L Dong (5334_CR4) 2020; 40 F Schaeffel (5334_CR30) 2012; 109 JC Yam (5334_CR15) 2019; 126 SA Read (5334_CR24) 2015; 56 CK Liang (5334_CR22) 2008; 16 MH Zhao (5334_CR36) 2020; 12 HC Cheng (5334_CR23) 2014; 22 FY Zhi (5334_CR33) 2018; 8 S Pugazhendhi (5334_CR11) 2020; 14 JA Summers (5334_CR29) 2013; 114 SC Harrington (5334_CR7) 2019; 103 QS You (5334_CR1) 2014; 92 L O'Donoghue (5334_CR6) 2010; 94 H Gao (5334_CR21) 2020; 38 JC Yam (5334_CR18) 2020; 127 Y Zhong (5334_CR14) 2015; 56 Z Zhang (5334_CR27) 2016; 6 JF Wu (5334_CR3) 2013; 8 DS Lam (5334_CR25) 2007; 48 DL Nickla (5334_CR31) 2010; 29 MT Kang (5334_CR37) 2016; 6 AN French (5334_CR5) 2013; 120 X Shang (5334_CR19) 2018; 5 J Wallman (5334_CR28) 1995; 35 ZCZY Gao Cen (5334_CR20) 2018; 6 XL Fan (5334_CR38) 2019; 17 HS Bi (5334_CR39) 2016; 10 CF Wildsoet (5334_CR12) 2019; 60 5334_CR10 A Chia (5334_CR16) 2016; 123 R Saxena (5334_CR9) 2015; 10 P Ganesan (5334_CR26) 2010; 5 DI Flitcroft (5334_CR35) 2019; 60 LA Jones (5334_CR13) 2007; 48 PC Wu (5334_CR32) 2013; 120 GV Murthy (5334_CR8) 2002; 43 BX Zhao (5334_CR34) 2013 |
| References_xml | – volume: 56 start-page: 1769 issue: 3 year: 2015 ident: 5334_CR2 publication-title: Invest Ophthalmol Vis Sci. doi: 10.1167/iovs.14-15737 – volume: 6 start-page: 28531 issue: 1 year: 2016 ident: 5334_CR37 publication-title: Sci Rep. doi: 10.1038/srep28531 – volume: 6 start-page: 34936 issue: 1 year: 2016 ident: 5334_CR27 publication-title: Sci Rep. doi: 10.1038/srep34936 – volume: 127 start-page: 910 issue: 7 year: 2020 ident: 5334_CR18 publication-title: Ophthalmology. doi: 10.1016/j.ophtha.2019.12.011 – volume: 40 start-page: 399 issue: 3 year: 2020 ident: 5334_CR4 publication-title: Retina. doi: 10.1097/IAE.0000000000002590 – volume: 48 start-page: 3524 issue: 8 year: 2007 ident: 5334_CR13 publication-title: Invest Ophthalmol Vis Sci. doi: 10.1167/iovs.06-1118 – volume: 114 start-page: 120 year: 2013 ident: 5334_CR29 publication-title: Exp Eye Res. doi: 10.1016/j.exer.2013.03.008 – volume: 60 start-page: M20 issue: 3 year: 2019 ident: 5334_CR35 publication-title: Invest Ophthalmol Vis Sci. doi: 10.1167/iovs.18-25957 – volume: 14 start-page: 853 year: 2020 ident: 5334_CR11 publication-title: Clin Ophthalmol. doi: 10.2147/OPTH.S241435 – volume: 123 start-page: 391 issue: 2 year: 2016 ident: 5334_CR16 publication-title: Ophthalmology. doi: 10.1016/j.ophtha.2015.07.004 – volume: 103 start-page: 1112 issue: 8 year: 2019 ident: 5334_CR7 publication-title: Br J Ophthalmol doi: 10.1136/bjophthalmol-2018-312573 – volume: 29 start-page: 144 issue: 2 year: 2010 ident: 5334_CR31 publication-title: Prog Retin Eye Res. doi: 10.1016/j.preteyeres.2009.12.002 – volume: 138 start-page: 50 issue: 1-2 year: 2008 ident: 5334_CR40 publication-title: Auton Neurosci. doi: 10.1016/j.autneu.2007.10.003 – volume: 120 start-page: 1482 issue: 7 year: 2013 ident: 5334_CR5 publication-title: Ophthalmology. doi: 10.1016/j.ophtha.2012.12.018 – volume: 5 start-page: 95 issue: 3 year: 2018 ident: 5334_CR19 publication-title: Medicines (Basel). doi: 10.3390/medicines5030095 – volume: 48 start-page: 376 issue: 1 year: 2007 ident: 5334_CR25 publication-title: Invest Ophthalmol Vis Sci. doi: 10.1167/iovs.06-0426 – volume: 126 start-page: 113 issue: 1 year: 2019 ident: 5334_CR15 publication-title: Ophthalmology. doi: 10.1016/j.ophtha.2018.05.029 – volume: 60 start-page: M106 issue: 3 year: 2019 ident: 5334_CR12 publication-title: Invest Ophthalmol Vis Sci. doi: 10.1167/iovs.18-25958 – volume: 35 start-page: 37 issue: 1 year: 1995 ident: 5334_CR28 publication-title: Vision Res. doi: 10.1016/0042-6989(94)E0049-Q – volume: 120 start-page: 1080 issue: 5 year: 2013 ident: 5334_CR32 publication-title: Ophthalmology. doi: 10.1016/j.ophtha.2012.11.009 – volume: 10 start-page: 854 issue: 35 year: 2016 ident: 5334_CR39 publication-title: Shandong J Trad Chin Med. – volume: 8 start-page: 907 issue: 38 year: 2018 ident: 5334_CR33 publication-title: Chin Acupunct Moxibust. – volume: 8 start-page: e82763 issue: 12 year: 2013 ident: 5334_CR3 publication-title: Plos One doi: 10.1371/journal.pone.0082763 – volume: 104 start-page: 1535 issue: 11 year: 2020 ident: 5334_CR17 publication-title: Br J Ophthalmol. doi: 10.1136/bjophthalmol-2019-315440 – volume: 38 start-page: 101067 year: 2020 ident: 5334_CR21 publication-title: Complement Ther Clin Pract. doi: 10.1016/j.ctcp.2019.101067 – volume-title: Name and location of auricular acupuncture points (WFAS STANDARD-002: 2013) year: 2013 ident: 5334_CR34 – volume: 12 start-page: 30 issue: 11 year: 2020 ident: 5334_CR36 publication-title: Chin Manipul Qigong Ther. – volume: 94 start-page: 1155 issue: 9 year: 2010 ident: 5334_CR6 publication-title: Br J Ophthalmol. doi: 10.1136/bjo.2009.176040 – volume: 22 start-page: 449 issue: 3 year: 2014 ident: 5334_CR23 publication-title: Complement Ther Med. doi: 10.1016/j.ctim.2014.03.004 – volume: 43 start-page: 623 issue: 3 year: 2002 ident: 5334_CR8 publication-title: Invest Ophthalmol Vis Sci. – ident: 5334_CR10 doi: 10.1136/bjophthalmol-2020-316475 – volume: 56 start-page: 3103 issue: 5 year: 2015 ident: 5334_CR24 publication-title: Invest Ophthalmol Vis Sci. doi: 10.1167/iovs.15-16446 – volume: 92 start-page: e398 issue: 5 year: 2014 ident: 5334_CR1 publication-title: Acta Ophthalmol. doi: 10.1111/aos.12299 – volume: 5 start-page: 759 issue: 6 year: 2010 ident: 5334_CR26 publication-title: Expert Rev Ophthalmol. doi: 10.1586/eop.10.67 – volume: 16 start-page: 305 issue: 6 year: 2008 ident: 5334_CR22 publication-title: Complement Ther Med. doi: 10.1016/j.ctim.2008.04.007 – volume: 109 start-page: 738 issue: 8 year: 2012 ident: 5334_CR30 publication-title: Ophthalmologe. doi: 10.1007/s00347-011-2497-4 – volume: 6 start-page: 375 issue: 28 year: 2018 ident: 5334_CR20 publication-title: J Tradit Chin Ophthalmol. – volume: 17 start-page: 109 year: 2019 ident: 5334_CR38 publication-title: Guid J Tradit Chin Med Pharm. – volume: 56 start-page: 4514 issue: 8 year: 2015 ident: 5334_CR14 publication-title: Invest Ophthalmol Vis Sci. doi: 10.1167/iovs.14-13935 – volume: 10 issue: 2 year: 2015 ident: 5334_CR9 publication-title: Plos One. |
| SSID | ssj0043934 ssj0017864 |
| Score | 2.2855318 |
| Snippet | Background
Nowadays, because of the increasing incidence, the prevention and control of myopia has become an urgent issue. In China, auricular acupressure has... Background Nowadays, because of the increasing incidence, the prevention and control of myopia has become an urgent issue. In China, auricular acupressure has... Nowadays, because of the increasing incidence, the prevention and control of myopia has become an urgent issue. In China, auricular acupressure has been... BackgroundNowadays, because of the increasing incidence, the prevention and control of myopia has become an urgent issue. In China, auricular acupressure has... Abstract Background Nowadays, because of the increasing incidence, the prevention and control of myopia has become an urgent issue. In China, auricular... |
| SourceID | doaj pubmedcentral proquest gale crossref springer |
| SourceType | Open Website Open Access Repository Aggregation Database Enrichment Source Index Database Publisher |
| StartPage | 387 |
| SubjectTerms | Acupressure Acupuncture Auricular acupressure Biomedicine Choroid Clinical trials Consent Disease prevention Eye diseases Health Sciences Hospitals Intervention Medicine Medicine & Public Health Myopia Myopia prevention and control Pediatric research Prevention Randomized clinical trial Research methodology Retina Statistics for Life Sciences Study Protocol Testing Traditional Chinese medicine Vision disorders in children |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Nb9QwELVQDxUXBAVEaIuMhMQBoiaON7G5bRFVhVROVOrN8qeI1Car3c0BfgU_uTOOs5BWwAXtZRXbu4k943kTz7wh5I1lUjdSlLkO4KvChudy3QifAzQ3ZeUtfPDVwMWX-vySf75aXP1W6gtjwkZ64HHiTopaMg2eNluYhmsZ9KIKtS-4DcYy20Qm0EIWkzM17sFgZSs-pciI-mQDO3U8rwTXGXNP83JmhiJb__09-X6c5J3D0miDzh6TRwk80uV400_IA98dkP2LdDz-lPxcDvF9nl5TbYcY4jqsPQVcSm--96tW01VibOo7qjtHU6A6bTs6ZXXH6-12Q8dID9pjU7_uWxdbMOmx0x-opmDkXH_T_vC7n7mGr7EKCEX2hx5E7Bm5PPv09eN5nkou5BaQyDaX3FYwx9I6rYMLzAYOkMSBEhsuS-4A7glhtA3CCllUDRPCGydMGQCWOeOq52Sv6zv_glADyt1gcR-wBtzUQTMtwT0zHnwkGB8yUk4roGziI8eyGNcq-iWiVuOqKVg1FVdNlRl5txuzGtk4_tr7FBd21xOZtOMFkC-V5Ev9S74y8hbFQqG-w-1ZndIW4CGROUstsXwzQx7DjBzNeoKe2nnzJFgq7RMbBeCxqDgm_Gbk9a4ZR2LsW-f7AfosAMMiUmMZaWYCOXuyeUvXfotc4UhYCB53Rt5Povvrz_88cy__x8wdkocsalydF80R2duuB38MCG5rXkVlvQV2LURD priority: 102 providerName: Directory of Open Access Journals – databaseName: ProQuest Central dbid: BENPR link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1ba9RAFB5qC-KLeMVolREEHzR0k8wmE0FkKy1F6CJioW_DXGugzazZzYP-Cn-y58xOUmKx7EvIzGwymXOdOec7hLzReS2rmmepdOCrgsAzqay4TcE0V1lhNfxwa-B0WZ6csS_n8_MdshxyYTCscpCJQVAbr3GP_ADU7KxgmBr5afUzxapReLo6lNCQsbSC-Rggxu6QPRDJHOh-7_Bo-fXbeK5Q8ZINqTO8PFiDBA_nmOBSY05qmk3UU0Dxvymrb8ZP_nOIGnTT8QNyPxqVdLGlgodkx7aPyN3TeGz-mPxZ9GGfT3ZU6j6EvvadpWCv0qtfftVIuopITr6lsjU0BrDTpqVDtne432zWdBsBQj02-c43JrRgMmQrP1BJQfkZf9X8tuPfXMJlqA5CERXCA-k9IWfHR98_n6SxFEOqwULZpDXTRe1krY2UzrhcOwamigHmVqzOmAEzkHMlteOa17Oiyjm3ynCVOTDXjDLFU7Lb-tY-I1QB01dY9Ae0BFOlk7mswW1TFnwnGO8Skg0rIHTEKcdyGZci-Cu8FNtVE7BqIqyayBLybhyz2qJ03Nr7EBd27IkI2-GG7y5EZFgxK-tcZjWINFUxCXOfF660M6ad0rmuWELeIlkIlAPwelrGdAaYJCJqiQWWdc4R3zAh-5OewL962jwQlojyYy2uqT0hr8dmHIkxca31PfSZg22LFlyekGpCkJOZTVva5kfAEEcgQ_DEE_J-IN3rh___yz2__V1fkHt54KUynVX7ZHfT9fYl2Gwb9Soy4l_K50I5 priority: 102 providerName: ProQuest – databaseName: SpringerLink Journals (ICM) dbid: U2A link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1bi9QwFA6ygvgiXrHrKhEEH7Q4TTNt4tsoLouwPjmwbyFXLew2Q2f6oL_Cn-w5mXSkrgoyL6VJZiY9t-8050LIC8ukbqWoSh3AVwWF50rdCl8CNDdV7S188NXA-afmbM0_XiwvclLYdop2n44kk6ZOYi2aN1vQtunMEdxfzB8twee5uQTfHcVxzVaT_gULW_MpPeaP62YmKFXqv66Pr8dI_nZQmuzP6V1yJwNHutpT-h654fv75NZ5Php_QH6sxvQuTw9U2zGFt46Dp4BJ6dW3uOk03eRqTbGnunc0B6nTrqdTRne63-22dB_lQSMOxSF2Lo1gwmOv31JNwcC5eNV994evuYTL1AGEYuWHCOz1kKxPP3x-f1bmdgulBRSyKyW3tQxaWqd1cIHZwAGOOBBgw2XFHUA9IYy2QVghF3XLhPDGCVMFgGTOuPoROepj7x8TakCwW2zsA5aAmyZopiW4ZsaDfwTrQ0GqiQLK5lrk2BLjUiWfRDRqTzUFVFOJaqoqyKvDms2-Esc_Z79Dwh5mYhXtdCMOX1QWSrVoJNOVBLVlWq5h78s6NH7BbTCW2ZYX5CWyhUJZh79ndU5ZgE1i1Sy1wtbNDGsYFuRkNhNk1M6HJ8ZSWUdsFQDHRc0x2bcgzw_DuBLj3nofR5izBPyKKI0VpJ0x5Gxn85G--5rqhGOxQvC2C_J6Yt1fP_73J3f8f9OfkNssyVZTLtoTcrQbRv8UcNrOPEti-RNrsjiK priority: 102 providerName: Springer Nature |
| Title | Auricular acupressure for myopia prevention and control in children and its effect on choroid and retina: a randomized controlled trial protocol |
| URI | https://link.springer.com/article/10.1186/s13063-021-05334-1 https://www.proquest.com/docview/2730340647 https://www.proquest.com/docview/2539208202 https://pubmed.ncbi.nlm.nih.gov/PMC8186104 https://doaj.org/article/0692a19425b74a9fa53f6e04cfbc2c74 |
| Volume | 22 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3ri9NAEB_OOxC_iE-MnmUFwQ8abZJtshFEcuXOo9BD1EK_Lfs8A72kpi14_hX-yc5uk0q8U5BCWvbRZLMzO7_ZnQfAcxXnIstZFAqLuioueDoUGTMhQnMZJUbhx20NTM_S0xmdzEfzPejSHbUvcHWtaufySc2axevv3y7fI8O_8wzP0jcrXIf9aSQqxs6zNERt6AAlU-qUsSndnSqg7E1o5zhzbb-ecPIx_K-u1FetJ_84QvWS6eQO3G4hJSm2NHAX9kx1D25O20Pz-_Cz2PhdPtEQoTbe8HXTGIJolVxc1stSkGUbx6muiKg0ac3XSVmRztfbl5frFdnaf5DaVdVNXWpf41whK_GWCIKiT9cX5Q-z-5sF_vS5QYiLCVEj4T2A2cnxl_Fp2CZiCBXik3WYU5XkVuRKC2G1jZWlCFQ0srakeUQ1gkDGpFCWKZYPkyxmzEjNZGQRrGmpk4ewX9WVeQREIstnLuUPyggqUytikaPSJg1qTtjfBhB1M8BVG6XcJctYcK-tsJRvZ43jrHE_azwK4OWuz3Ibo-OfrY_cxO5auvjavqBuznnLrnyY5rGIclzQZEYFjn2U2NQMqbJSxSqjAbxwZMEdXeLjKdE6M-AgXTwtXrikzrGLbhjAYa8lcq_qV3eExTvi5wgphwl1bsABPNtVu57OIq4y9QbbjBDZOvwWB5D1CLI3sn5NVX71EcRdGEPUwwN41ZHu75v__c09_r_mT-BW7HkrDYfZIeyvm415ighuLQdwI5tnAzgoisnnCX4fHZ99_ISl43Q88LsieP0wjwaeffE6i4tfedxKtw |
| linkProvider | Scholars Portal |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtR3batRAdKhbUF_EK0arjqD4oKG5zCYTochWW7a2u4i00Lfp3KKBNln3gtSv8Iv8Ns-ZnWyJxb6VvIScmWxmz5lzmXMj5JVOCpkXPA5lCbYqMDwTypzbEFRzFadWw4VHA6NxNjxin4_7x2vkT5sLg2GVLU90jNo0Gs_IN0HMRinD1MgPkx8hdo1C72rbQkP61gpmy5UY84kd-_b8J5hws629T4Dv10myu3P4cRj6LgOhBuE7Dwum06KUhTZSlqZMdMlAChugW8WKmBnQcDhXUpdc8yJK84RzqwxXcQmaiFEmhffeIOsMM1x7ZH17Z_zl68qPkfOMtak6PNucgcRwflMw4TEHNow74tB1DbgsGy7Ha_7jtHWycPcuueOVWDpYUt09smbr--TmyLvpH5Dfg4U7V5RTKvXChdouppaCfkzPzptJJenEV45qaiprQ33APK1q2maXu-fVfEaXESe0QVAzbSrjIJh8Wcv3VFIQtqY5q37Z1WtO4dZ1I6FYhaIBUn9Ijq4FKY9Ir25q-5hQBUwmxyZDIJWYykqZyALMRGXBVoP5ZUDiFgNC-7ro2J7jVDj7iGdiiTUBWBMOayIOyNvVnMmyKsiVo7cRsauRWNHbPWim34RnECLKikTGBbBQlTMJa--nZWYjpkulE52zgLxBshDId-DztPTpE7BIrOAlBthGOsF6igHZ6IwEfqG74JawhOdXM3GxuwLycgXGmRiDV9tmAWP6oEujxpgEJO8QZGdlXUhdfXc1y7FwIlj-AXnXku7Fj___n3ty9be-ILeGh6MDcbA33n9KbiduX2VhlG-Q3ny6sM9AX5yr535TUnJy3XzgL8Q9gLA |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1baxQxFA51C8UX8YqjVSMoPuiwc9uZjFBka7u01i5FLPQtzVUH2pl1L0j9Ff4uf5XnZDNbxmLfyr4sk2Q22XPynXOScyHklUpKUZQsDoUFWxUAT4eiYCYE1VzGqVHwwaOBw3G-d5x9OhmcrJE_bSwMulW2mOiAWjcKz8j7IGajNMPQyL71bhFHO6MPkx8hVpDCm9a2nIbwZRb0lks35oM8DszFTzDnZlv7O0D710ky2v36cS_0FQdCBYJ4HpaZSksrSqWFsNomymYgkTXwsMzKONOg7TAmhbJMsTJKi4QxIzWTsQWtREudwntvkfUC59kj69u746MvqzuNguVZG7bD8v4MpIe7QwVzHuNhw7gjGl0Fgaty4qrv5j8XuE4uju6SO16hpcMlB94ja6a-TzYO_ZX9A_J7uHBnjGJKhVo4t9vF1FDQlen5RTOpBJ34LFJNTUWtqXeep1VN20hz97yaz-jS-4Q22NRMm0q7FgzErMV7KigIXt2cV7_M6jVn8NVVJqGYkaIBtn9Ijm-EKI9Ir25q85hQCYBTYMEhkFCZzK1IRAkmozRgt8F4G5C4pQBXPkc6luo4485WYjlfUo0D1bijGo8D8nY1ZrLMEHJt720k7KonZvd2D5rpN-7Bgkd5mYi4BDiVRSZg7YPU5ibKlJUqUUUWkDfIFhwxCKanhA-lgEViNi8-xJLSCeZWDMhmpydgh-o2t4zFPXbN-OVOC8jLVTOORH-82jQL6DMAvRq1xyQgRYchOyvrttTVd5e_HJMoxhGs4l3Lupc__v9_7sn1c31BNgAP-Of98cFTcjtx2yoPo2KT9ObThXkGquNcPvd7kpLTm4aBv4QQhNw |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Auricular+acupressure+for+myopia+prevention+and+control+in+children+and+its+effect+on+choroid+and+retina%3A+a+randomized+controlled+trial+protocol&rft.jtitle=Trials&rft.au=Han%2C+Rong&rft.au=Kong%2C+Xie-he&rft.au=Zhao%2C+Feng&rft.au=Yang%2C+Yan-ting&rft.date=2021-06-07&rft.pub=BioMed+Central&rft.eissn=1745-6215&rft.volume=22&rft.issue=1&rft_id=info:doi/10.1186%2Fs13063-021-05334-1&rft.externalDocID=10_1186_s13063_021_05334_1 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1745-6215&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1745-6215&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1745-6215&client=summon |