Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 102; no. 50; pp. 18017 - 18022
• Main Authors: Aboobaker, A.A, Tomancak, P, Patel, N, Rubin, G.M, Lai, E.C
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 13.12.2005; National Acad Sciences
• Subjects: Animals; Biological Sciences; Drosophila; Drosophila - embryology; Drosophila - genetics; Drosophila melanogaster; embryo (animal); embryogenesis; Embryonic growth stage; Embryos; Gene expression; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genetic loci; Genomes; Hindgut; Hybridization; In Situ Hybridization; loci; Mesoderm; MicroRNA; MicroRNAs - genetics; MicroRNAs - metabolism; Nervous system; Ribonucleic acid; RNA; transcription (genetics); Vertebrates

MicroRNAs (miRNAs) are an extensive class of regulatory RNA whose specific functions in animals are generally unknown. Although computational methods have identified many potential targets of miRNAs, elucidating the spatial expression patterns of miRNAs is necessary to identify the sites of miRNA ac...