Arabinoxylan consumption decreases postprandial serum glucose, serum insulin and plasma total ghrelin response in subjects with impaired glucose tolerance

• Published in: European journal of clinical nutrition Vol. 61; no. 3; pp. 334 - 341
• Main Authors: Garcia, A.L, Otto, B, Reich, S.C, Weickert, M.O, Steiniger, J, Machowetz, A, Rudovich, N.N, Mohlig, M, Katz, N, Speth, M
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.03.2007; Nature Publishing; Nature Publishing Group
• Subjects: administration & dosage; Adults; Aged; arabinoxylan; Arabinoxylans; Area Under Curve; Biological and medical sciences; blood; blood glucose; Blood Glucose - metabolism; Body mass index; Body size; Clinical Nutrition; Consumption; Cross-Over Studies; Diabetes; Diabetes mellitus; Diabetes. Impaired glucose tolerance; Diet; dietary carbohydrate; Dietary Fiber; Dietary Fiber - administration & dosage; Dietary Supplements; Diseases of the digestive system; drug therapy; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Epidemiology; Etiopathogenesis. Screening. Investigations. Target tissue resistance; experimental diets; Female; Ghrelin; Glucose; Glucose Intolerance; Glucose Intolerance - blood; Glucose Intolerance - drug therapy; Glucose Intolerance - metabolism; Glucose tolerance; Hormones; Humans; Insulin; Insulin - blood; Internal Medicine; Intervention; Male; Medical sciences; Medicine; Medicine & Public Health; men; Metabolic Diseases; Metabolic response; metabolic studies; Metabolism; Middle Aged; Nutrition; nutritional intervention; original-article; Peptide Hormones; Peptide Hormones - blood; Placebos; Plasma; Postprandial Period; postprandial state; Public Health; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Single-Blind Method; Solubility; Time Factors; triacylglycerols; Triglycerides; Triglycerides - blood; women; Xylans; Xylans - administration & dosage; impaired glucose tolerance; ghrelin; soluble dietary fibre; Endocrinopathy; Consumption; Human; Pancreatic hormone; Postprandial; Soluble form; Glucose; Insulin; Feeding; Appetite stimulant; Diet therapy; Ghrelin; Serum; Biological effect; Impaired glucose tolerance; Arabinoxylan

Objective: Arabinoxylan (AX) consumption is associated with metabolic improvement during diabetes and with modulation of ghrelin, an orexigenic gut hormone. The effect of AX consumption on ghrelin secretion in disturbed metabolic states is unknown. Therefore, we investigated the postprandial respons...