NAFLD mark: an accurate model based on microRNA-34 for diagnosis of non-alcoholic fatty liver disease patients

• Published in: Journal of Genetic Engineering and Biotechnology Vol. 19; no. 1; pp. 157 - 7
• Main Authors: Mohamed, Amal A., El-Demery, Ahmed, Al-Hussain, Eman, Mousa, Shroouk, Halim, Ahmed Abdel, Mostafa, Sahar M., Abdelghany, Reda S., Mahmoud, Seham M., Elkady, Mohammad A., Raafat, Khaled, Hassnine, Alshymaa A., Omran, Mohamed M.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 18.10.2021; Springer; Springer Nature B.V; Elsevier
• Subjects: Alanine aminotransferase; Biomarkers; Biomedical Engineering and Bioengineering; Biopsy; Body mass index; Body size; C-reactive protein; Chi-square test; Cholesterol; Diagnosis; Diagnostic systems; Discriminant analysis; Engineering; Ethylenediaminetetraacetic acid; Fatty liver; Laboratories; Laboratory tests; Liver; Liver diseases; Medical research; Medicine, Experimental; MicroRNA; MicroRNA-34; MicroRNAs; miRNA; mRNA; Multivariate analysis; Non-alcoholic fatty liver disease; Regression analysis; Ribonucleic acid; RNA; Statistical analysis; Triglycerides; Variables; Egypt; Taiwan; United States > US; Germany; Body mass index; Alanine aminotransferase; C-reactive protein; Non-alcoholic fatty liver disease; MicroRNA-34; Cholesterol

Background It remains essential for non-alcoholic fatty liver (NAFLD) patients, to develop a sensitive and specific diagnostic model. Data regarding the use of micro (mi)RNA-34 for NAFLD diagnosis are few. Routine clinical assessment, laboratory tests were done for Egyptian individuals ( n = 314) we...