Losing the dogmatic view of cerebral autoregulation

• Published in: Physiological reports Vol. 9; no. 15; pp. e14982 - n/a
• Main Authors: Brassard, Patrice, Labrecque, Lawrence, Smirl, Jonathan D., Tymko, Michael M., Caldwell, Hannah G., Hoiland, Ryan L., Lucas, Samuel J. E., Denault, André Y., Couture, Etienne J., Ainslie, Philip N.
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.08.2021; John Wiley and Sons Inc; Wiley
• Subjects: Animals; arterial blood pressure; autoregulatory curve; Blood flow; Blood Pressure; cerebral autoregulation; Cerebral blood flow; Cerebrovascular Circulation; Homeostasis; Humans; Hypertension; Invited Review; Invited Reviews; Lassen; Oxygen Consumption; Physiology; Science education; cerebral blood flow; Lassen; arterial blood pressure; autoregulatory curve; cerebral autoregulation

In 1959, Niels Lassen illustrated the cerebral autoregulation curve in the classic review article entitled Cerebral Blood Flow and Oxygen Consumption in Man. This concept suggested a relatively broad mean arterial pressure range (~60–150 mmHg) wherein cerebral blood flow remains constant. However, t...