32磷-玻璃微球治疗裸鼠人肝癌移植瘤的超微结构观察和立体定量学研究

R735.7; 目的探讨32P-GMS对肝癌的治疗作用和超微结构影响.方法建立裸鼠人肝癌移植瘤后用32P-GMS进行治疗, 取治疗后瘤组织进行电镜观察和立体定量学研究.结果实验组瘤细胞大量坏死,部分瘤细胞出现了高分化肝癌的形态特征.实验组线粒体和粗面内质网体密度、毛细胆管和微绒毛面密度高于对照组(P＜0.01、0.05、0.01).结论研究表明32P-GMS抗肝癌作用明显,并具有较好的促分化功能....

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Published in肿瘤防治研究 Vol. 29; no. 4; pp. 293 - 294
Main Authors 张东生, 刘璐, 万美玲, 李群慧
Format Journal Article
LanguageChinese
Published 210009,南京,东南大学医学院电镜室%210009,南京,东南大学医学院放免中心 2002
Subjects
肝肿瘤
32磷-玻璃微球
立体定量学
超微结构
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Abstract R735.7; 目的探讨32P-GMS对肝癌的治疗作用和超微结构影响.方法建立裸鼠人肝癌移植瘤后用32P-GMS进行治疗, 取治疗后瘤组织进行电镜观察和立体定量学研究.结果实验组瘤细胞大量坏死,部分瘤细胞出现了高分化肝癌的形态特征.实验组线粒体和粗面内质网体密度、毛细胆管和微绒毛面密度高于对照组(P＜0.01、0.05、0.01).结论研究表明32P-GMS抗肝癌作用明显,并具有较好的促分化功能.
AbstractList R735.7; 目的探讨32P-GMS对肝癌的治疗作用和超微结构影响.方法建立裸鼠人肝癌移植瘤后用32P-GMS进行治疗, 取治疗后瘤组织进行电镜观察和立体定量学研究.结果实验组瘤细胞大量坏死,部分瘤细胞出现了高分化肝癌的形态特征.实验组线粒体和粗面内质网体密度、毛细胆管和微绒毛面密度高于对照组(P＜0.01、0.05、0.01).结论研究表明32P-GMS抗肝癌作用明显,并具有较好的促分化功能.
Author 刘璐
李群慧
张东生
万美玲
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DocumentTitle_FL An ultrastructural and morphometric study on the effect of phosphorus-32 glass microspheres (32P-GMS) on the human hepatocellular carcinoma in nude mice
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32磷-玻璃微球
立体定量学
超微结构
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Snippet R735.7; 目的探讨32P-GMS对肝癌的治疗作用和超微结构影响.方法建立裸鼠人肝癌移植瘤后用32P-GMS进行治疗,...
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Title 32磷-玻璃微球治疗裸鼠人肝癌移植瘤的超微结构观察和立体定量学研究
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