Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer - Giamas, Georgios; Filipović, Aleksandra; Jacob, Jimmy; Messier, Walter; Zhang, Hua; Yang, Dongyun; Zhang, Wu; Shifa, Belul Assefa; Photiou, Andrew; Tralau-Stewart, Cathy; Castellano, Leandro; Green, Andrew R; et al. (Nature medicine, 2011)
Keywords: 631/67/1059/602; 631/80/86; 692/699/67/1347; Animals; Antineoplastic Agents, Hormonal - therapeutic use; Biomedical and Life Sciences; Biomedicine; Breast cancer; Breast Neoplasms - drug therapy; Breast Neoplasms - genetics; Breast Neoplasms - metabolism; Breast Neoplasms - physiopathology; Cancer Research; Care and treatment; Drug Resistance, Neoplasm - genetics; Estrogen; Estrogen Receptor alpha - biosynthesis; Estrogen Receptor alpha - metabolism; Estrogen Receptor alpha - physiology; Female; Gene Expression Regulation, Neoplastic - physiology; Genes; Genetic aspects; Genotype; Humans; Infectious Diseases; letter; Metabolic Diseases; Mice; Mice, Nude; Molecular Medicine; Neoplasm Transplantation; Neurosciences; Physiological aspects; Polymorphism, Genetic - genetics; Protein kinases; Receptors; RNA, Small Interfering - physiology; Tamoxifen - therapeutic use; United States; United Kingdom