Mechanistic insights into CDCA gene family-mediated glioblastoma progression: implications for diagnosis, prognosis, and therapeutic targeting

• Published in: Hereditas Vol. 162; no. 1; p. 43
• Main Author: Liu, Chang
• Format: Journal Article
• Language: English
• Published: England BioMed Central 20.03.2025; BMC
• Subjects: Apoptosis; Biomarkers; Biomarkers, Tumor - genetics; brain; Brain cancer; brain neoplasms; Brain Neoplasms - diagnosis; Brain Neoplasms - genetics; Brain Neoplasms - pathology; Brain research; Brain tumors; Cancer; Cancer therapies; CDCA genes; Cell cycle; Cell Cycle Proteins - genetics; Cell division; Cell Line, Tumor; Cell Proliferation; Chromosomes; Datasets; Diagnosis; Disease Progression; DNA methylation; Gene expression; Gene Expression Regulation, Neoplastic; gene targeting; genes; Genomics; Glioblastoma; Glioblastoma - diagnosis; Glioblastoma - genetics; Glioblastoma - pathology; Glioma; Humans; Immune cells; immune evasion; Immunomodulation; Medical prognosis; methylation; Molecular modelling; Mutation; mutational analysis; Penicillin; Prognosis; RNA; Therapeutic applications; Therapeutic targets; therapeutics; Treatment; Wound healing; United States > US; CDCA genes; Treatment; Diagnosis; Immune cells; Glioblastoma

Glioblastoma (GBM) is a highly aggressive brain tumor characterized by poor prognosis and limited therapeutic options. Understanding the molecular mechanisms driving GBM progression is essential for developing more effective diagnostic and therapeutic approaches. Specifically, investigating Cell Div...