The serine protease inhibitor camostat inhibits influenza virus replication and cytokine production in primary cultures of human tracheal epithelial cells - Yamaya, Mutsuo; Shimotai, Yoshitaka; Hatachi, Yukimasa; Lusamba Kalonji, Nadine; Tando, Yukiko; Kitajima, Yasuo; Matsuo, Kaori; Kubo, Hiroshi; Nagatomi, Ryoichi; Hongo, Seiji; Homma, Morio; Nishimura, Hidekazu (Pulmonary pharmacology & therapeutics, 2015)
Keywords: Aged; Airway epithelial cell; Animals; Aprotinin - pharmacology; Camostat; Cell culture; Cells, Cultured; Dogs; Epithelial Cells - drug effects; Epithelial Cells - virology; Female; Gabexate - analogs & derivatives; Gabexate - pharmacology; Humans; Influenza; Influenza A Virus, H1N1 Subtype - isolation & purification; Influenza A Virus, H3N2 Subtype - isolation & purification; Influenza, Human - drug therapy; Influenza, Human - virology; Interleukin; Madin Darby Canine Kidney Cells; Male; Medical Education; Middle Aged; Pulmonary/Respiratory; RNA, Viral - metabolism; Serine protease; Serine Proteinase Inhibitors - pharmacology; Trachea - cytology; Trachea - virology; Virus Replication - drug effects; Cell culture; RT; AEBSF; Interleukin; CLEIA; SARS-CoV; Camostat; TNF; LPS; IFN; DMEM; LDH; DF-12; ANOVA; MDCK; PBS; Airway epithelial cell; TMPRSS; IL; MOI; F-12; USG; PVDF; TCID; PBS-T; SDS-PAGE; MEM; Influenza; KIU; Serine protease; HA; HAT; COPD; ELISA; phosphate buffered saline with Tween ® 20; hemagglutinin; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; 4-(2-aminoethyl)-benzenesulfonyl fluoride; Ultroser G; mixture of Dulbecco's modified Eagle's medium-Ham's F-12 medium; polyvinylidene difluoride; Kallikrein Inhibitor Unit; lactate dehydrogenase; Dulbecco's modified Eagle's medium; severe acute respiratory syndrome coronavirus; human trypsin-like protease; lipopolysaccharide; Eagle's minimum essential medium; room temperature; Ham's F-12 medium; multiplicity of infection; analysis of variance; interferon; chemiluminescent enzyme immunoassay; tumor necrosis factor; phosphate buffered saline; enzyme-linked immunosorbent assay; Madin Darby Canine Kidney; tissue culture infective dose; transmembrane protease serine S1 member; chronic obstructive pulmonary disease