Integrated single-cell analysis revealed immune dynamics during Ad5-nCoV immunization

• Published in: Cell discovery Vol. 7; no. 1; pp. 64 - 17
• Main Authors: Cao, Qiqi, Wu, Shipo, Xiao, Chuanle, Chen, Shuzhen, Chi, Xiangyang, Cui, Xiuliang, Tang, Hao, Su, Wenru, Zheng, Yingfeng, Zhong, Jiayong, Li, Zhaomin, Li, Fang, Chen, Haijia, Hou, Lihua, Wang, Hongyang, Wen, Wen
• Format: Journal Article
• Language: English
• Published: Singapore Springer Singapore 10.08.2021; Springer Nature B.V; Nature Publishing Group
• Subjects: 631/1647/48; 631/250; Antibodies; Biomedical and Life Sciences; Cell Biology; Cell Culture; Cell Cycle Analysis; Cell Physiology; Cell-mediated immunity; Complementarity-determining region 3; Coronaviruses; COVID-19; COVID-19 vaccines; Humoral immunity; Immune response; Immune status; Immunization; Infectious diseases; Interferon; Leukocytes (mononuclear); Life Sciences; Monoclonal antibodies; Peripheral blood mononuclear cells; Public health; Severe acute respiratory syndrome coronavirus 2; Spike protein; Stem Cells; Vaccines

Coronavirus disease 2019 (COVID-19), driven by SARS-CoV-2, is a severe infectious disease that has become a global health threat. Vaccines are among the most effective public health tools for combating COVID-19. Immune status is critical for evaluating the safety and response to the vaccine, however...