Comparing methods for plasma HDV RNA quantification in bulevirtide-treated and untreated patients with HDV

• Published in: JHEP reports Vol. 7; no. 3; p. 101299
• Main Authors: Anolli, Maria Paola, Uceda Renteria, Sara, Degasperi, Elisabetta, Facchetti, Floriana, Sambarino, Dana, Borghi, Marta, Perbellini, Riccardo, Soffredini, Roberta, Monico, Sara, Callegaro, Annapaola, Lampertico, Pietro
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.03.2025; Elsevier
• Subjects: AltoStar; Antiviral therapy; Bulevirtide; Chronic hepatitis delta; EurobioPlex; Gastroenterology and Hepatology; HDV; HDV RNA; Nucleic acid; PCR; Robogene; Antiviral therapy; Chronic hepatitis delta; Robogene; EurobioPlex; HDV RNA; HDV; AltoStar; Bulevirtide; PCR; Nucleic acid

Accurate HDV RNA quantification is crucial for diagnosis and management of chronic hepatitis delta (CHD), yet a significant variability between assays exists. We compared three methods to quantify HDV RNA levels in untreated and bulevirtide (BLV)-treated patients with CHD. Frozen plasma from untreat...