Metformin ameliorates polycystic ovary syndrome in a rat model by decreasing excessive autophagy in ovarian granulosa cells via the PI3K/AKT/mTOR pathway - Xu, Bo; Dai, Wenjie; Liu, Ling; Han, Hang; Zhang, Jingjing; Du, Xing; Pei, Xiuying; Fu, Xufeng (Endocrine Journal, 2022)
Keywords: 1-Phosphatidylinositol 3-kinase; AKT protein; Autophagy; Excessive autophagy; Granulosa cells; Hydrogen peroxide; Infertility; Metformin; Ovarian granulosa cells; Ovaries; Ovulation; Oxidative stress; PI3K/AKT/mTOR; Polycystic ovary syndrome; Signal transduction; TOR protein; Polycystic ovary syndrome; Ovarian granulosa cells; Excessive autophagy; PI3K/AKT/mTOR; Metformin