Generation of β-Amyloid in the Secretory Pathway in Neuronal and Nonneuronal Cells
The cellular mechanism underlying the generation of β-amyloid in Alzheimer disease and its relationship to the normal metabolism of the amyloid precursor protein are unknown. In this report, we show that 3- and 4-kDa peptides derived from amyloid precursor protein are normally secreted. Epitope mapp...
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Published in | Proceedings of the National Academy of Sciences - PNAS Vol. 90; no. 5; pp. 2092 - 2096 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Washington, DC
National Academy of Sciences of the United States of America
01.03.1993
National Acad Sciences |
Subjects | |
Online Access | Get full text |
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