Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN - Wang, Sheng-Kai; Liang, Pi-Hui; Astronomo, Rena D; Hsu, Tsui-Ling; Hsieh, Shie-Liang; Burton, Dennis R; Wong, Chi-Huey (Proceedings of the National Academy of Sciences - PNAS, 2008)
Keywords: Antibodies; Antibodies, Monoclonal - metabolism; Antiviral agents; Antivirals; Biochemistry; Biological Sciences; Carbohydrate Metabolism; Carbohydrates; CD4-positive T-lymphocytes; Cell Adhesion Molecules - metabolism; Dendrimers; Dendrimers - chemical synthesis; Dendrimers - chemistry; Dendrimers - metabolism; dendritic cells; epitopes; Flow Cytometry; Glycoproteins; Glycosylation; HIV; HIV 1; HIV-1 - metabolism; Human immunodeficiency virus; Human immunodeficiency virus 1; Humans; Immune system; Infections; Inhibitory concentration 50; Jurkat Cells; lectins; Lectins, C-Type - metabolism; Ligands; Lymph nodes; Mannose - chemical synthesis; Mannose - chemistry; Mannose - metabolism; microarray technology; monoclonal antibodies; Physical Sciences; Polymers - chemistry; Polymers - metabolism; Polysaccharides; Receptors, Cell Surface - metabolism; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; T cell receptors; T lymphocytes; Vaccination; vaccine development; Vaccines; viruses